Grant winners - 13 November 2014

November 13, 2014

Arts and Humanities Research Council

Science in Culture Innovation Awards

Metamorphoses: gaming art and science with Ovid

Dark matters: an interrogation of thresholds of (im)perceptibility through theoretical cosmology, fine art and anthropology of science


Royal Society

University Research Fellowships

CMB spectral distortions as a new probe of early Universe physics

Reprogramming of epigenetic memory during plant regeneration

Inventory of the vegetated land surface using remote sensing technologies


Leverhulme Trust

International Network Grants

Assembling the early Palaeozoic terranes of Japan


New interpretations on the Angevin world

Economic integration and social change in the Islamic world system, 800-1000 CE

Imaginaries of the future: historicising the present

Social sciences

International network of implicit leadership theory (ILT) scholars

In detail

Munir Pirmohamed, University of Liverpool

Medical Research Council
Clinical Research Infrastructure Initiative: Technologies for Stratified Medicines

Award winner: Munir Pirmohamed
Institution: University of Liverpool
Value: £5,000,000

Applying innovative technologies to improve the benefit-risk ratio of drugs: developing a national resource underpinned by the infrastructure of the MRC Centre for Drug Safety Science (CDSS)

All drugs are associated with variability in response: some patients do not respond to drugs, while others develop side-effects or adverse drug reactions (ADRs). New state-of-the-art technologies funded by the initiative will build upon this infrastructure at the CDSS by helping to identify the best treatments for patients based on how drug responses vary, how diseases differ between individuals, and how this information relates to variation in clinical outcomes. “With this funding we will look at patient samples using the latest and most sensitive technologies available in different ‘experimental’ systems,” said Munir Pirmohamed, deputy director of the CDSS. “These range from cutting-edge imaging techniques, to experiments on single cells. By combining these data with careful clinical observations of patients, we will ultimately be able to tailor treatments for individual patients so that they are not only effective but also safe.”

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