Array of errors, but Spanish chemist stands by concept

Watchdog recommends retraction of Science paper after 'indications' of bad practice. Paul Jump writes

August 19, 2010

A Spanish scientist has admitted to making mistakes but is standing by his science after an ethics committee recommended the retraction of a paper in the journal Science.

Manuel Ferrer, a researcher at the Institute of Catalysis and Petrochemistry in Madrid, was one of two corresponding authors of a paper published last October that described a technique called a reactome array, which purported to be able to identify all enzyme activity in a cell.

However, chemists identified flaws in the paper and claimed the technique was impossible. Science reacted in December with an "editorial expression of concern" and a request for the authors' institutions to check the data.

The ethics committee of the Spanish National Research Council, which funds Dr Ferrer's institute, has now concluded that the paper should be retracted because it did not have "all the necessary experimental support for the conclusions".

The committee highlighted "clear indications of deviation from good scientific practices" in the conduct of experiments and the treatment of data, and apparent contradictions in the authors' responses to questions from Science. But attributing blame to individuals would need further investigation, it added.

Science has now written to all 18 of the paper's authors. A spokeswoman for the journal confirmed that the letter "mentioned the option" of retraction. But she added that Science was still waiting for a "definitive response" from the current and previous employers of the paper's other corresponding author, Peter Golyshin: Bangor University in the UK and the Helmholtz Centre for Infection Research in Braunschweig, Germany, respectively. A spokeswoman for Bangor said that its report would be ready next week.

Professor Golyshin could not be contacted, but Dr Ferrer told Times Higher Education that he had accepted "from the beginning" that the paper contained mistakes. "We had a huge amount of information and maybe I couldn't handle it all myself ... but I thought it was better to show the potential application of the technology," he said.

He added that no decision had been taken about a retraction, but was confident that new experiments he was working on would verify his chemistry.

The ethics committee also noted that "a number of scientists" were convinced the array worked. It also expressed concern about Science's peer-review procedures.

The committee's leader, Pere Puigdomenech, told THE that the paper's mistakes would have been picked up by an organic chemist, "but we understand it is difficult to appoint referees ... when reviewing a complex multidisciplinary article".

Meanwhile, The Boston Globe reported last week that a 2002 paper by Harvard University psychologist Marc Hauser, which investigated whether monkeys could follow rules, is to be retracted from the journal Cognition after a Harvard investigation found evidence of unspecified scientific misconduct.

Science has asked for more information before deciding what to do about a paper Professor Hauser published in the journal in 2007. He is on leave for the next academic year.

paul.jump@tsleducation.com.

You've reached your article limit

Register to continue

Registration is free and only takes a moment. Once registered you can read a total of 6 articles each month, plus:

  • Sign up for the editor's highlights
  • Receive World University Rankings news first
  • Get job alerts, shortlist jobs and save job searches
  • Participate in reader discussions and post comments
Register

Have your say

Log in or register to post comments

Featured Jobs

Analyst

Greenwich School Of Management Ltd

PhD Research Fellow in Medical Physics

Norwegian University Of Science & Technology -ntnu

Senior Knowledge Officer

European Association For International Education

Postdoctoral position in Atmospheric and Space Physics

Norwegian University Of Science & Technology -ntnu
See all jobs

Most Commented

Doctoral study can seem like a 24-7 endeavour, but don't ignore these other opportunities, advise Robert MacIntosh and Kevin O'Gorman

Matthew Brazier illustration (9 February 2017)

How do you defeat Nazis and liars? Focus on the people in earshot, says eminent Holocaust scholar Deborah Lipstadt

Improvement, performance, rankings, success

Phil Baty sets out why the World University Rankings are here to stay – and why that's a good thing

Warwick vice-chancellor Stuart Croft on why his university reluctantly joined the ‘flawed’ teaching excellence framework

people dressed in game of thrones costume

Old Germanic languages are back in vogue, but what value are they to a modern-day graduate? Alice Durrans writes