LaSalle College Vancouver

Institution/Department Mohammed VI Polytechnic University Chemical & biochemical sciences.green process engineering Research Unit on Microbiome and Host-Pathogen Interactions Project Overview: We are looking for a highly motivated Postdoctoral Research Fellow to join our interdisciplinary team focused on antimicrobial resistance (AMR). The selected candidate will have a vital role in an innovative project that aims to map the resistome and clarify the mechanisms of multidrug resistance across diverse microbiomes—comprising clinical, environmental, and host-associated microbial communities. This project seeks to comprehend how antimicrobial resistance genes (ARGs) disseminate within microbial populations via horizontal gene transfer (HGT) and mobile genetic elements (MGEs) and how these processes affect human health, particularly regarding colorectal cancer (CRC). Key Responsibilities: Perform shotgun metagenomics and whole-genome sequencing (WGS) on microbial samples from various environments (clinical, environmental, tumor-associated microbiomes). Develop and implement bioinformatics pipelines for resistome, mobilome, and virulome profiling using tools such as MEGARes, CARD, VFDB, and PlasmidFinder. Investigate horizontal gene transfer (HGT) dynamics and plasmid-mediated dissemination of ARGs across microbial communities. Conduct phylogenetic and comparative genomic analyses to uncover the evolution of multidrug resistance in pathogenic bacteria. Analyze co-occurrence networks between resistance genes, virulence factors, and mobile elements in microbiome datasets. Collaborate with clinical partners and microbiome researchers to integrate multi-omics data for comprehensive resistome analysis. Publish high-quality research articles and present findings at international conferences. Contribute to grant writing and development of new research proposals. Required Qualifications: PhD in Microbial Genomics, Bioinformatics, Molecular Microbiology, Infectious Disease Biology, or a related field. Proven experience with high-throughput sequencing technologies (Illumina, Nanopore) and metagenomic analyses. Strong background in bioinformatics tools for microbiome analysis (QIIME2, Kraken2, MetaPhlAn) and AMR gene identification (MEGARes, CARD, ResFinder). Proficiency in Python, R, or Perl, with experience in Linux/Unix environments. Solid understanding of antimicrobial resistance mechanisms, horizontal gene transfer, and mobile genetic elements. Evidence of scientific publications in peer-reviewed journals. Excellent communication and teamwork skills. Preferred Qualifications: Experience in clinical microbiome research, oncology microbiomes, or environmental resistome surveillance. Familiarity with spatial metagenomics, single-cell microbiome analysis, or multi-omics data integration. Knowledge of machine learning approaches for resistome prediction or biomarker discovery is a plus. Why Join Us? Access to cutting-edge technologies (mass spectrometry, next-gen sequencing, high-performance computing). Work on high-impact research addressing one of the urgent challenges in global health—antimicrobial resistance. Collaborate with a multidisciplinary team of microbiologists, bioinformaticians, clinicians, and data scientists. Opportunity to lead high-profile publications and contribute to international consortia. Career development support, including grant writing, conference funding, and training opportunities. Application Process: Applicants should submit the following in a single PDF file: A Cover Letter explaining their interest and fit for the position A detailed Curriculum Vitae (CV) Names and contact details of 2–3 references Up to three key publications (optional)

Job/Project description: The College of Computing at Mohamed VI Polytechnic University (UM6P), Benguerir, Morocco is seeking applications for a Postdoctoral Research position with a research focus in Computational Biology. The candidates should be highly motivated and have a Ph.D. in computational biology or any related field, and a good knowledge of molecular biology. The candidate will be part of the bioinformatics laboratory at the college of computing (bioinformatics.um6p.ma). The project aims to build a simulator for the response of mutations at different levels. The candidate will be responsible for building a simulator that allows researchers to see the response of their proposed mutations at DNA, RNA and protein levels. The candidate should have a deep understanding of the central dogma of biology and the effect of mutations. He/she would also be required to have a sound computational background, especially in the area of simulations. Criteria of the candidate: PhD in the field of Computational Biology, or related fields Strong publication record in leading international journals Excellent background in molecular biology Excellent programming skills Experience in computational analysis of molecular data Experience with high performance computing  Aptitude for team work, problem solving and collaborative relationships Excellent verbal and written skills in English Organizational dexterity and ability to prioritize and manage multiple goals Positive attitude in changing fast-paced environments Active participation in improvement of self, processes and goals About UM6P: Mohammed VI Polytechnic University (UM6P,https://www.um6p.ma/en) is an international higher education institution, established to provide research and innovation at the service of education and development for Morocco and the African continent. It has a state-of-the-art campus at the heart of the Green City of Benguerir, near Marrakesh. UM6P academics and staff enjoy strong research funding, moderate teaching loads, and excellent facilities. Its research approach is transdisciplinary with an emphasis on international collaboration. Many of our research programs run as start-ups. OCP group (http://www.ocpgroup.ma/en/home), a world leader in fertilizer production, is a major starter client for the University providing capital and research funds. In parallel, a new portfolio of clients is growing with the development of an R&D cluster around the University and a growing number of international partnerships. Applications and selection procedure: Applications must contain: A cover letter indicating the position applied for and the main research interests. A detailed CV. A brief research statement. Contact information of 3 references (Applicants are assumed to have obtained their references’ consent to be contacted for this matter). About the employer Mohammed VI Polytechnic University is an institution dedicated to research and innovation in Africa and aims to position itself among world-renowned universities in its fields The University is engaged in economic and human development and puts research and innovation at the forefront of African development. A mechanism that enables it to consolidate Morocco’s frontline position in these fields, in a unique partnership-based approach and boosting skills training relevant for the future of Africa. Located in the municipality of Benguerir, in the very heart of the Green City, Mohammed VI Polytechnic University aspires to leave its mark nationally, continentally, and globally. Areas of Research Computational Biology Bioinformatics Computer Science Molecular Biology

The Chemical and Biochemical Sciences-Green Process Engineering at the University of Mohammed VI Polytechnic Benguerir Morocco seeks Postdoctoral applicants in Proteomics and Drug Development.  Job/Project Description: Angiogenesis, the formation of new blood vessels, is crucial angiogenesis in tumor growth, proliferation, invasion, and metastasis. Advances in molecular biology have identified critical biomolecules involved in this process, making anti-angiogenic treatments a promising cancer therapy strategy. Common treatments include monoclonal antibodies and tyrosine kinase inhibitors targeting the VEGF pathway. However, challenges like adverse events, drug resistance, tumor recurrence, and lack of biomarkers limit their effectiveness. Further research into angiogenesis mechanisms, drug development, and combination therapies is needed to enhance therapeutic outcomes. In recent years, a significant research focus has been combining angiogenic and immune checkpoint inhibitors. Compared to monotherapies, this approach has shown improved clinical benefits in hepatocellular carcinoma and renal cell carcinoma patients treated with a combination of PD-1 and VEGFR-2 inhibitors. To address the challenges of anti-angiogenic treatment and explore emerging strategies to enhance its therapeutic benefits, we are focusing on the development of novel anti-angiogenic drugs against specific biomarkers as potential clinical candidates.To meet our objectives, we have collaborated with colleagues from Canadian, USA, and European universities, and we are equipped with OMICS state-of-the-art technologies. Fellowship Competitive international compensation and health insurance Expected activities. Conduct research as part of the project team. Applicant requirements Ph.D. in bioinformatics, proteomics, drug design and development, genomics, mathematics, computer science, or related fields Complete CV Short research statement (summary) Interest in intracellular organelle/cell biology, signal transduction, proteomics, drug design, or related fields Good knowledge of cell biological and molecular biological methods Experience in bioinformatics tools related to proteomics and drug design. Aptitude for teamwork, problem-solving solving, and collaborative relationships Verbal and written skills in English Positive attitude in changing fast-paced environments.