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Bluefield State College

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Hong Kong

Ref.: 532242
Work type: Full-time
Department: School of Nursing (20800)
Categories: Senior Research Staff & Post-doctoral Fellow

Applications are invited for appointment as Post-doctoral Fellow in the School of Nursing (Ref: 532242) (to commence as soon as possible for 12 - 18 months, with the possibility of renewal subject to funding availability and satisfactory performance)

Applicants should possess a Ph.D. degree in Health Science, Sport Science, Psychology, Public Health or Gerontology preferably with experience in coordinating research projects, data management, and research dissemination.  They should have a good command of written and spoken English; good interpersonal and organizational skills; and be attentive to details, responsible, and able to work independently.

The appointee will work on research projects related to health service research and/or global healthy aging promotion, and assist in research grant application, project leadership, data analysis and research dissemination. 

A highly competitive salary commensurate with qualifications and experience will be offered, in addition to annual leave and medical benefits. 

The University only accepts online application for the above post.  Applicants should apply online and upload an up-to-date C.V.  Review of applications will start as soon as possible and continue until July 15, 2025, or until the post is filled, whichever is earlier.


The University of Hong Kong

Finland, Helsingfors (Helsinki)

We are recruiting a

Doctoral Researcher

to the project ‘Targeting transcription elongation to modify the prostate cancer tumor immune micro-environment’ to the research group Transcriptional Rewiring in Cancer led by Harri Itkonen (University of Helsinki). The project is pursued in close collaboration with Professor Ian G Mills’ research group based in University of Oxford and it is funded by Prostate Cancer UK. The position is for 3 years, and we hope that the candidate starts in autumn 2025.

Background

The research in Itkonen laboratory is focused on how the information embedded in the genome is decoded through transcription, and how the defects in this process can be used as a basis for therapy. Currently, we are probing how the crosstalk between transcriptional kinases and other factors regulating RNA polymerase II activity function in normal and cancer cells. In particular, we are interested in the kinases that promote transcription elongation, CDK9 and CDK12, and highlight few examples that are particularly relevant for the current project. We discovered that CDK9 inhibition stimulates transcription of short mRNAs (Gondane & al. 2025, PMID: 40186208) and leads to excessive splicing defects (Hu & al., 2021, PMID: 34592899), which the cell interprets as a viral infection (Yalala & al. 2024, PMID: 38661032). In our projects, we make extensive use of comprehensive transcriptional profiling, including RNA-seq, SLAM-seq, alternative splicing analysis, combined with epigenetic profiling using ChIP-seq, FAIRE-seq and more recently also ATAC-seq (for examples, see Itkonen & al. 2020, PMID: 3261155; Gondane & al. 2022, PMID: 35164752,Gondane & al. 2023, PMID: 36975490, and Liang & al. 2024, PMID: 38775167).

For further information, please refer to our research groups’ web pages:

https://www.helsinki.fi/en/researchgroups/transcriptional-rewiring-in-cancer

https://www.nds.ox.ac.uk/team/ian-mills

Project

Prostate cancer is immunologically cold, which means that the body’s own immune system fails to detect and eradicate the cancer cells. We have discovered that the drug-induced defects in transcription elongation activate immunogenic signaling in prostate cancer cells. In particular, this can be achieved by inhibiting CDK9 using compounds already assessed in clinical trials against other cancers.

Our main aim in this project is to develop CDK9 inhibitor-based treatment against prostate cancer for durable response. To achieve this, we will model how both normal and cancer cells respond to CDK9 inhibition, and if the response can be augmented using immunomodulatory and / or other strategies.

The project is divided so that the organoid experiments and bioinformatics are performed in University of Helsinki, while the animal experimentation is performed in University of Oxford. The project utilizes a number of sequencing techniques including RNA-seq, SLAM-seq, scSLAM-seq, and ‘Breaks Labeling In Situ and Sequencing (BLISS)’.

The candidate

We are seeking a motivated Bioinformatics graduate who wants to expand their expertise to cancer research / molecular biology. The proposed project is intended for an MSc-level person who wishes to acquire PhD degree. PhD Trainees in my laboratory typically graduate within 3-4 years with competitive publication output, and we put great emphasis on planning the project with clear milestones set in the beginning. This strategy allows the Trainees and me to reflect on the progress and to make adjustments as need be. Project involves significant work together with collaborating groups based in Oxford (Mills) and Switzerland (Clémentine LeMagnen). The appointee will be based in Helsinki and the project includes research visit to Switzerland to acquire specific expertise required for the project execution.

Qualification requirements

The ideal candidate has an MSc degree from Bioinformatics, but applicable other degrees are also considered.

Essential


	Applicant must hold an MSc degree.
	Proven experience on using command line-based tools.
	Fluent oral and written communication skills in English.


In addition, the additional qualifications will be an asset


	Experience from using virtual machines.
	Experience in analyzing the data generated using the techniques mentioned in the section ‘Project’.
	Working experience (in any sector, also unrelated to the field of education)
	Demonstrable experience in presenting own work (conferences, social media etc).
	Knowledge on cancer biology.


Personal skills


	Genuine interest in science.
	Ability to work in a team and independently.


The appointee should either already have the right to pursue a doctoral degree at the University of Helsinki by the start of the appointment or apply for the right and obtain it within the probationary period of six months of their appointment. If the candidate does not already have the right to pursue a doctoral degree at the University of Helsinki, it must be applied for separately: www.helsinki.fi/en/research/doctoral-education/the-application-process-in-a-nutshell.

The requirements for pursuing a doctoral degree at the University of Helsinki can be found at https://www.helsinki.fi/en/research/doctoral-education/eligibility-and-educational-documents. The appointee will be based in Helsinki.

What we offer

Project is expected to start in autumn 2025, as a fixed 3-year position. A 6-month trial period will be applied.

How to apply

Applications should be submitted through the University of Helsinki Recruitment System via the "Apply now" button. Internal applicants (i.e., current employees of the University of Helsinki) submit their applications by using the Employee Login button.

Please send your application with following enclosures:


	CV (maximally 2 pages).
	Cover letter (max 1-page, scientific background, motivation for the position and research interests).
	Copies of educational certificates (academic transcripts only – please ascertain that the grading system is clearly explained, include both diploma and grades you have received from all the courses taken during BSc and MSc education).
	2-3 references (name, institution, e-mail, telephone number, and relation to the candidate).


The closing date for applications is July 20th 2025.

We encourage informal inquiries: harri.itkonen@helsinki.fi and ian.mills@nds.ox.ac.uk

About us

The Faculty of Medicine promotes high quality scientific research. It provides research-based undergraduate and postgraduate education in medicine, dentistry, psychology and logopedics, and an international Master's Programme in Translational Medicine. It also offers psychotherapist education. In addition to its teaching and research activities, the faculty serves as a significant expert organisation in the healthcare sector and contributes to the discourse on ethics in the field. The faculty aims to be one of the best medical research faculties in the world, while reinforcing its status as a distinguished institution of multidisciplinary education in healthcare.  https://www.helsinki.fi/en/faculty-of-medicine.

The Faculty of Medicine at the University of Helsinki constitutes the academic medical centre together with HUS Helsinki University Hospital and the Helsinki Institute of Life Science (HiLIFE). This medical centre has been successful in international comparisons, ranking among the top 10 medical campuses in Europe and the top 50 globally.

JOIN US TO BUILD A BETTER WORLD – TOGETHER!  

#HelsinkiUniCareers


University of Helsinki

The Advanced Biomedical Instrumentation Centre Limited (ABIC) is a collaborative effort coordinated by the University of Hong Kong (HKU) undertaking R&D projects with universities and companies globally. The aim of ABIC is to develop new and disruptive technologies that will meet the needs of the healthcare sector and contribute to human health.

Applications are invited for appointment as AI Engineering Specialist (Software as a Medical Device (SaMD) and Artificial Intelligence) (Ref.: H01/2025/063)

We are seeking an expert to play a pivotal role in our medical engineering efforts. You will drive and shape the development of groundbreaking Software as a Medical Device (SaMD) products and leverage the power of artificial intelligence to revolutionize diagnostics, treatment, and patient care.

What You'll Do


	Lead the design and development of AI/ML algorithm
	Focus on electrophysiology and brain-computer interface (BCI) data analysis and algorithms
	Apply your expertise in machine learning (especially deep learning) to develop, train, validate, and optimize algorithms for a variety of medical applications.
	Architect and develop SaMD products, with a focus on US FDA product registration (510(k), De Novo, PMA) and fulfilling international standards (e.g., ISO 13485, IEC 62304)
	Employ software engineering best practices and adhere to relevant software development cycle standards
	Guide architectural decisions, technology choices, and development methodologies
	Collaborate with cross-functional teams (product, clinical, regulatory) to ensure alignment


What is Required


	Bachelor, Master or Ph.D. degree in Computer Science, Data Science, Biomedical Engineering, Information Engineering, or a related field with a strong emphasis on software development and AI/ML.
	Proven experiences in BCI related data analysis and algorithms
	Proven experience in handling brain-related electrophysiological signals such as ECoG, neural spikes or EEG as a plus
	6+ years of experience in software development for medical applications, with 3+ years focused on SaMD and a proven track record of developing and deploying AI/ML algorithms in a regulated environment.
	Expert-level proficiency in machine learning, particularly deep learning, with hands-on experience using frameworks and tools, such as TensorFlow, PyTorch, Keras, etc.
	Strong programming skills in languages such as Python, C++, R, and Java.
	Experience with cloud computing platforms (AWS, Azure, GCP) and their services relevant to SaMD.
	In-depth understanding of the medical device development lifecycle and relevant regulations (FDA or EU MDR).
	Experience with SaMD development, verification, validation, and regulatory approval. Knowledge of QMS principles and ISO 13485.


Work mode


	Full-time / part-time, details can be negotiated
	Located in Hong Kong, or the Silicon Valley area in California in US
	Highly competitive compensation will be offered.  


Applicants should submit their up-to-date C.V., quoting the job reference number, with information on current/expected remuneration and availability, to pklc@hku.hk. Review of applications will commence as soon as possible and until the posts are filled.

The personal data provided in your application process will be used for recruitment and other employment-related purpose. The personal data may be transferred and disclosed to, and used by the affiliated entities of Advanced Biomedical Instrumentation Centre Limited for the above purposes.

We are an equal opportunities employer and welcome applications from all qualified candidates.


Advanced Biomedical Instrumentation Centre Ltd

Ireland, Maynooth

Department: Music
Vacancy ID: 035562
Closing Date: 20-Jul-2025

Maynooth University is committed to a strategy in which the primary University goals of excellent research and scholarship and outstanding education are interlinked and equally valued.

We are seeking an excellent Executive Assistant to join our staff in the Department of Music. The successful candidate will provide administrative support for the Department and will report directly to the Head of Department and the Administrative Officer.

Salary:

Executive Assistant (2025): €31,713 – €47,950 p.a. (13 points)

Appointments will be made in accordance with public sector pay provisions.

Closing Date:

23:30hrs (local Irish time) on Sunday, 20th July 2025.

Applications must be submitted by the closing date and time specified above. Any applications which are still in progress at the closing time on the specified closing date will be cancelled automatically by the system.

Late applications will not be accepted.

Maynooth University is an equal opportunities employer

The position is subject to the Statutes of the University


Maynooth University

United Kingdom, Southampton

We have an exciting opportunity within our Halls Maintenance Team for a Multi-Skilled Operative to join our established team to carry out the delivery of planned, reactive maintenance and minor small works on our Halls of Residences sites.

Main duties include:


	Undertake emergency, planned and general maintenance works such as decoration, minor plumbing including drainage, flooring and furnishing repairs, minor brick and plaster repairs, and carpentry
	Undertake investigatory fault finding and use initiative to find solutions and make repairs on a range of internal and external building fabric
	Complete works to a high standard to align to industry best practice and Health & Safety procedures including risk assessments and method statements
	Accessing work via mobile handheld devices, updating status in a live environment to capture hours worked and materials used


What we are looking for:

The successful candidate will hold a City and Guilds qualification and/or minimum NVQ 2 qualification and served an apprenticeship in one primary core building trade with the confidence and ability to undertake a full range of duties in at least two other secondary building related trade disciplines. They will also have experience of maintenance and repairs in a live dynamic environment plus have a customer focused ‘right first time’ attitude and flexible approach to working. Experience of using a CAFM system to access and complete work requests would be an advantage. They should be familiar with H&S legislation and understanding of risk assessments, method statements, COSHH assessments and how to apply these to planned and reactive maintenance. 

A full driving license to travel to other local sites is essential.  

What we can offer you:

We offer some fantastic benefits including generous annual leave (plus University closure days and bank holidays), company pension scheme, discounted private healthcare and dental, company sick pay, cycle to work scheme, learning and development opportunities, options for flexible working, excellent family leave arrangements, employee wellbeing service,  a wide variety of on and off-campus arts and culture facilities and access to a range of staff discounts and offers at local shops, restaurants and service providers.  

We reserve the right to close the application period early subject to number of candidates received.


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