University of Manchester

Ref.: 533909 Work type: Full-time Department: School of Biomedical Sciences (22600) Categories: Senior Research Staff & Post-doctoral Fellow Applications are invited for appointment as Post-doctoral Fellow in the School of Biomedical Sciences (Ref.: 533909), to commence as soon as possible for two years, with the possibility of renewal subject to satisfactory performance and funding availability. Applicants should possess a PhD degree in Biomedical Sciences, Biochemistry, Chemistry or a related discipline. They should have strong background and research experience in at least one of the following areas: (1) Chemical biology; (2) Anticancer drug research; (3) Cancer biology; (4) Mass spectrometry; (5) Proteomics. They should be self-motivated, responsible and able to work independently as well as in a team. The appointee will work on interdisciplinary projects related to the development of novel therapeutic agents targeting cancer-related proteins for therapy. In particular, the appointee will utilize chemoproteomics to discover new druggable hotspots in liver cancer, which can facilitate the development of novel anticancer therapeutics. The appointee will have a good opportunity to learn and perform state-of-the-art research for drug target identification and drug development. Enquiries about the duties of the post should be sent to Professor Clive Chung at cyschung@hku.hk. An overview of the research in Professor Clive Chung’s lab can be found here: http://clivechunglab.com/. A highly competitive salary commensurate with qualifications and experience will be offered, in addition to annual leave and medical benefits.  The University only accepts online application for the above post at the University’s Careers site (https://jobs.hku.hk). Applicants should apply online and upload an up-to-date C.V.  Review of applications will start from December 25, 2025 and continue until March 10, 2026, or until the post is filled, whichever is earlier.   The University is an equal opportunities employer and is committed to equality, ethics, inclusivity, diversity and transparency

The Role The Research Culture and Evaluation Manager will support the generation, delivery and evaluation of research culture activities across the Flourish at Durham portfolio, enabling colleagues to thrive and flourish. The post-holder will work within the research culture team and in collaboration with other key units such as the Researcher Development team in the Durham Centre for Academic Development (DCAD) and the EDI Team to: Support the development, communication and implementation of the University's new Charter for Researchers alongside the Concordat to Support the Career Development of Researchers; Enable the implementation, data analysis and evaluation of research culture initiatives and actions in academic departments and university research institutes; Work across academic departments and professional services directorates to support the joined-up approach to enabling research ambition, with a particular focus on early and mid-career research culture development; Embed evaluation into research culture activities across Flourish at Durham; Contribute to both internal and external networks that enable research culture progress and undertake professional development and good practice exchange in research and innovation culture. We believe this role presents an excellent opportunity for candidates to develop a career in research and innovation culture. We welcome applications from individuals with strong transferable skills and experience from different careers and sectors, potentially in organisational change, researcher or research development, or data analysis and evaluation methods. You may have worked in research administration for a number of years and be looking for another opportunity. You may have recently finished a PhD or postdoctoral role and wish to explore career paths beyond academia. You may work outside of HE but have experience of organisational change or people development. We welcome applications from individuals who feel they meet the essential criteria below, regardless of background or experience. The base location for this role is Boldon House, our exciting new professional services hub.Boldon House is situated on the outskirts of Durham near the Arnison Centre in Pity Me. Boldon House brings a number of professional services teams together in a vibrant office environment which supports collaborative working and is designed to embrace hybrid working. To find out more, visit the project webpage: . Further information about the role and the responsibilities is at the bottom of this job description. Working arrangements This role is fulltime (35 hours/week) but we will consider requests for flexible working arrangements including potential job shares. It is expected that this role will be predominantly face-to-face on campus, and the successful applicant will be prepared to locate to the northeast of England. There will be some scope for hybrid working arrangements in agreement with line manager, but this post will not be fully remote.

About us: The post will be based in the KCL Social, Genetic, and Developmental Psychiatry Centre, within the Institute of Psychiatry, Psychology and Neuroscience (IoPPN). The Social, Genetic & Developmental Psychiatry (SGDP) Centre is uncovering the genetic and environmental influences on mental health and psychiatric disorders. Our research encompasses behavioural genetics, molecular genetics, experimental psychology and psychiatry, and neuroimaging. Scientists at the SGDP lead some of the UK’s foremost longitudinal cohort and twin studies including TEDS, eRISK, Dunedin, IMAGEN and GLAD. The NIHR BioResource Centre Maudsley leads the NIHR BioResource for Mental Health. We focus on recruiting participants experiencing mental health conditions, as well as healthy people. Alongside GLAD MHG and The GLAD study, Prof. Breen’s team boasts an accomplished portfolio of clinical and genetic studies which aim to improve treatment and outcomes for those affected by anxiety, depression, eating disorders and other mental health conditions.  About the role: We are seeking an enthusiastic and motivated Senior Laboratory Technician to support the large-scale biobanking of blood samples for the Genetic Links to Anxiety and Depression (GLAD) Study Mental Health Goals (MHG) OMICs Programme. This project represents the largest multiomics programme for severe depression worldwide, designed to accelerate discovery in psychiatric genomics and to provide a long-term resource for the research community. This position provides an exciting opportunity to work in a cross-disciplinary environment, applying cutting-edge biobanking and genomic technologies to mental health research. The role will centre on the receipt, processing, and storage of thousands of blood samples, ensuring accurate sample tracking and data linkage within our ISO17025-accredited pipelines. The postholder will also support semi-automated sample processing, DNA extraction, and preparation of material for downstream genomic assays including Illumina genotyping and Oxford Nanopore sequencing. Working closely with a multidisciplinary team of laboratory scientists, bioinformaticians, and study coordinators, the postholder will ensure the highest quality of biobanking and data integrity. Responsibilities will include contributing to laboratory reports, maintaining detailed records, and supporting quality assurance processes.  This role offers the opportunity to contribute to flagship mental health genetics studies, helping to create a resource that will underpin psychiatric and population health research for years to come. This is a full time post (35 hours per week), and you will be offered a fixed term contract for 2 years with the possibility to extend. Earliest start date is the 1st of April 2026. About you: To be successful in this role, we are looking for candidates to have the following skills and experience: Essential criteria BSc and/or MSc in a relevant subject and/or sufficient relevant experience. Good knowledge of DNA/RNA and blood processing techniques Good knowledge of high throughput DNA sequencing and genotyping technologies Clear spoken and written communication skills, with proficient computer use and strong interpersonal and influencing/behavioural skills. Good knowledge of molecular biology and molecular genetics Previous experience of work in a Research Laboratory Experience with we-lab molecular genetic methods Developed ability to work well in a team environment as well as independently, manage own workload, pattern of work and resources Desirable criteria Experience with genomic data on Linux and R Experience with LIMS Experienced in following compliance procedures with relevant regulations governing the service, completing risk assessments to inform actions and ensure a safe and environmentally sustainable workplace. Knowledge of environmental impacts of laboratory work and an interest in reducing the negative impacts. Downloading a copy of our Job Description Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the page. This document will provide information of what criteria will be assessed at each stage of the recruitment process. Further information: We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible. To find out how our managers will review your application, please take a look at our ‘How we Recruit’ pages. Grade and Salary: £39,076 - £41,761 per annum, including London Weighting Allowance Job ID: 133525 Close Date: 11-Jan-2026 Contact Person: Gerome Breen / Anna Carnegie Contact Details: gerome.breen@kcl.ac.uk / anna.carnegie@kcl.ac.uk