The next big bang: biology and medicine papers

Paper 1

Title: Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cells

Author(s): Nowakowski, TJ (Nowakowski, Tomasz J.); Pollen, AA (Pollen, Alex A.); Di Lullo, E (Di Lullo, Elizabeth); Sandoval-Espinosa, C (Sandoval-Espinosa, Carmen); Bershteyn, M (Bershteyn, Marina); Kriegstein, AR (Kriegstein, Arnold R.)

Source: CELL STEM CELL  Volume: 18  Issue: 5  Pages: 591-596  DOI: 10.1016/j.stem.2016.03.012  Published: MAY 5 2016  

Times Cited in Web of Science Core Collection: 43

Total Times Cited: 44

Paper 2

Title: The 3.8 angstrom resolution cryo-EM structure of Zika virus

Author(s): Sirohi, D (Sirohi, Devika); Chen, ZG (Chen, Zhenguo); Sun, L (Sun, Lei); Klose, T (Klose, Thomas); Pierson, TC (Pierson, Theodore C.); Rossmann, MG (Rossmann, Michael G.); Kuhn, RJ (Kuhn, Richard J.)

Source: SCIENCE  Volume: 352  Issue: 6284  Pages: 467-470  DOI: 10.1126/science.aaf5316  Published: APR 22 2016  

Times Cited in Web of Science Core Collection: 42

Total Times Cited: 46

Paper 3

Title: Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection

Author(s): Bayer, A (Bayer, Avraham); Lennemann, NJ (Lennemann, Nicholas J.); Ouyang, YS (Ouyang, Yingshi); Bramley, JC (Bramley, John C.); Morosky, S (Morosky, Stefanie); Marques, ETD (De Azeved Marques, Ernesto Torres, Jr.); Cherry, S (Cherry, Sara); Sadovsky, Y (Sadovsky, Yoel); Coyne, CB (Coyne, Carolyn B.)

Source: CELL HOST & MICROBE  Volume: 19  Issue: 5  Pages: 705-712  DOI: 10.1016/j.chom.2016.03.008  Published: MAY 11 2016  

Times Cited in Web of Science Core Collection: 39

Total Times Cited: 39

Paper 4

Title: Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3

Author(s): Dang, J (Dang, Jason); Tiwari, SK (Tiwari, Shashi Kant); Lichinchi, G (Lichinchi, Gianluigi); Qin, Y (Qin, Yue); Patil, VS (Patil, Veena S.); Eroshkin, AM (Eroshkin, Alexey M.); Rana, TM (Rana, Tariq M.)

Source: CELL STEM CELL  Volume: 19  Issue: 2  Pages: 258-265  DOI: 10.1016/j.stem.2016.04.014  Published: AUG 4 2016  

Times Cited in Web of Science Core Collection: 34

Total Times Cited: 34

Paper 5

Title: Structure of the thermally stable Zika virus

Author(s): Kostyuchenko, VA (Kostyuchenko, Victor A.); Lim, EXY (Lim, Elisa X. Y.); Zhang, SJ (Zhang, Shuijun); Fibriansah, G (Fibriansah, Guntur); Ng, TS (Ng, Thiam-Seng); Ooi, JSG (Ooi, Justin S. G.); Shi, J (Shi, Jian); Lok, SM (Lok, Shee-Mei)

Source: NATURE  Volume: 533  Issue: 7603  Pages: 425-+  DOI: 10.1038/nature17994  Published: MAY 19 2016  

Times Cited in Web of Science Core Collection: 34

Total Times Cited: 35

Paper 6

Title: Vertical transmission of Zika virus targeting the radial glial cells affects cortex development of offspring mice

Author(s): Wu, KY (Wu, Kong-Yan); Zuo, GL (Zuo, Guo-Long); Li, XF (Li, Xiao-Feng); Ye, Q (Ye, Qing); Deng, YQ (Deng, Yong-Qiang); Huang, XY (Huang, Xing-Yao); Cao, WC (Cao, Wu-Chun); Qin, CF (Qin, Cheng-Feng); Luo, ZG (Luo, Zhen-Ge)

Source: CELL RESEARCH  Volume: 26  Issue: 6  Pages: 645-654  DOI: 10.1038/cr.2016.58  Published: JUN 2016  

Times Cited in Web of Science Core Collection: 33

Total Times Cited: 33

Paper 7

Title: Characterization of Lethal Zika Virus Infection in AG129 Mice

Author(s): Aliota, MT (Aliota, Matthew T.); Caine, EA (Caine, Elizabeth A.); Walker, EC (Walker, Emma C.); Larkin, KE (Larkin, Katrina E.); Camacho, E (Camacho, Erwin); Osorio, JE (Osorio, Jorge E.)

Source: PLOS NEGLECTED TROPICAL DISEASES  Volume: 10  Issue: 4  Article Number: e0004682  DOI: 10.1371/journal.pntd.0004682  Published: APR 2016  

Times Cited in Web of Science Core Collection: 30

Total Times Cited: 30

Paper 8

Title: A Susceptible Mouse Model for Zika Virus Infection

Author(s): Dowall, SD (Dowall, Stuart D.); Graham, VA (Graham, Victoria A.); Rayner, E (Rayner, Emma); Atkinson, B (Atkinson, Barry); Hall, G (Hall, Graham); Watson, RJ (Watson, Robert J.); Bosworth, A (Bosworth, Andrew); Bonney, LC (Bonney, Laura C.); Kitchen, S (Kitchen, Samantha); Hewson, R (Hewson, Roger)

Source: PLOS NEGLECTED TROPICAL DISEASES  Volume: 10  Issue: 5  Article Number: e0004658  DOI: 10.1371/journal.pntd.0004658  Published: MAY 2016  

Times Cited in Web of Science Core Collection: 25

Total Times Cited: 25

Paper 9

Title: Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody

Author(s): Dai, LP (Dai, Lianpan); Song, J (Song, Jian); Lu, XS (Lu, Xishan); Deng, YQ (Deng, Yong-Qiang); Musyoki, AM (Musyoki, Abednego Moki); Cheng, HJ (Cheng, Huijun); Zhang, YF (Zhang, Yanfang); Yuan, Y (Yuan, Yuan); Song, H (Song, Hao); Haywood, J (Haywood, Joel); Xiao, HX (Xiao, Haixia); Yan, JH (Yan, Jinghua); Shi, Y (Shi, Yi); Qin, CF (Qin, Cheng-Feng); Qi, JX (Qi, Jianxun); Gao, GF (Gao, George F.)

Source: CELL HOST & MICROBE  Volume: 19  Issue: 5  Pages: 696-704  DOI: 10.1016/j.chom.2016.04.013  Published: MAY 11 2016  

Times Cited in Web of Science Core Collection: 23

Total Times Cited: 25

Paper 10

Title: Zika Virus Infects Human Placental Macrophages

Author(s): Quicke, KM (Quicke, Kendra M.); Bowen, JR (Bowen, James R.); Johnson, EL (Johnson, Erica L.); McDonald, CE (McDonald, Circe E.); Ma, HL (Ma, Huailiang); O'Neal, JT (O'Neal, Justin T.); Rajakumar, A (Rajakumar, Augustine); Wrammert, J (Wrammert, Jens); Rimawi, BH (Rimawi, Bassam H.); Pulendran, B (Pulendran, Bali); Schinazi, RF (Schinazi, Raymond F.); Chakraborty, R (Chakraborty, Rana); Suthar, MS (Suthar, Mehul S.)

Source: CELL HOST & MICROBE  Volume: 20  Issue: 1  Pages: 83-90  DOI: 10.1016/j.chom.2016.05.015  Published: JUL 13 2016  

Times Cited in Web of Science Core Collection: 20

Total Times Cited: 20

Paper 11

Title: Structural basis of potent Zika-dengue virus antibody cross-neutralization

Author(s): Barba-Spaeth, G (Barba-Spaeth, Giovanna); Dejnirattisai, W (Dejnirattisai, Wanwisa); Rouvinski, A (Rouvinski, Alexander); Vaney, MC (Vaney, Marie-Christine); Medits, I (Medits, Iris); Sharma, A (Sharma, Arvind); Simon-Loriere, E (Simon-Loriere, Etienne); Sakuntabhai, A (Sakuntabhai, Anavaj); Cao-Lormeau, VM (Cao-Lormeau, Van-Mai); Haouz, A (Haouz, Ahmed); England, P (England, Patrick); Stiasny, K (Stiasny, Karin); Mongkolsapaya, J (Mongkolsapaya, Juthathip); Heinz, FX (Heinz, Franz X.); Screaton, GR (Screaton, Gavin R.); Rey, FA (Rey, Felix A.)

Source: NATURE  Volume: 536  Issue: 7614  Pages: 48-+  DOI: 10.1038/nature18938  Published: AUG 4 2016  

Times Cited in Web of Science Core Collection: 19

Total Times Cited: 19

Paper 12

Title: Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling

Author(s): Grant, A (Grant, Alesha); Ponia, SS (Ponia, Sanket S.); Tripathi, S (Tripathi, Shashank); Balasubramaniam, V (Balasubramaniam, Vinod); Miorin, L (Miorin, Lisa); Sourisseau, M (Sourisseau, Marion); Schwarz, MC (Schwarz, Megan C.); Sanchez-Seco, MP (Paz Sanchez-Seco, Mari); Evans, MJ (Evans, Matthew J.); Best, SM (Best, Sonja M.); Garcia-Sastre, A (Garcia-Sastre, Adolfo)

Source: CELL HOST & MICROBE  Volume: 19  Issue: 6  Pages: 882-890  DOI: 10.1016/j.chom.2016.05.009  Published: JUN 8 2016  

Times Cited in Web of Science Core Collection: 18

Total Times Cited: 18

Paper 13

Title: Zika virus damages the human placental barrier and presents marked fetal neurotropism

Author(s): de Noronha, L (de Noronha, Lucia); Zanluca, C (Zanluca, Camila); Azevedo, MLV (Viola Azevedo, Marina Luize); Luz, KG (Luz, Kleber Giovanni); dos Santos, CND (Duarte dos Santos, Claudia Nunes)

Source: MEMORIAS DO INSTITUTO OSWALDO CRUZ  Volume: 111  Issue: 5  Pages: 287-+  DOI: 10.1590/0074-02760160085  Published: MAY 2016  

Times Cited in Web of Science Core Collection: 17

Total Times Cited: 18

Paper 14

Title: Vaccine protection against Zika virus from Brazil

Author(s): Larocca, RA (Larocca, Rafael A.); Abbink, P (Abbink, Peter); Peron, JPS (Peron, Jean Pierre S.); Zanotto, PMD (Zanotto, Paolo M. de A.); Iampietro, MJ (Iampietro, M. Justin); Badamchi-Zadeh, A (Badamchi-Zadeh, Alexander); Boyd, M (Boyd, Michael); Ng'ang'a, D (Ng'ang'a, David); Kirilova, M (Kirilova, Marinela); Nityanandam, R (Nityanandam, Ramya); Mercado, NB (Mercado, Noe B.); Li, ZF (Li, Zhenfeng); Moseley, ET (Moseley, Edward T.); Bricault, CA (Bricault, Christine A.); Borducchi, EN (Borducchi, Erica N.); Giglio, PB (Giglio, Patricia B.); Jetton, D (Jetton, David); Neubauer, G (Neubauer, George); Nkolola, JP (Nkolola, Joseph P.); Maxfield, LF (Maxfield, Lori F.); De La Barrera, RA (De La Barrera, Rafael A.); Jarman, RG (Jarman, Richard G.); Eckels, KH (Eckels, Kenneth H.); Michael, NL (Michael, Nelson L.); Thomas, SJ (Thomas, Stephen J.); Barouch, DH (Barouch, Dan H.)

Source: NATURE  Volume: 536  Issue: 7617  Pages: 474-+  DOI: 10.1038/nature18952  Published: AUG 25 2016  

Times Cited in Web of Science Core Collection: 16

Total Times Cited: 17

Paper 15

Title: A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection

Author(s): Barrows, NJ (Barrows, Nicholas J.); Campos, RK (Campos, Rafael K.); Powell, ST (Powell, Steven T.); Prasanth, KR (Prasanth, K. Reddisiva); Schott-Lerner, G (Schott-Lerner, Geraldine); Soto-Acosta, R (Soto-Acosta, Ruben); Galarza-Munoz, G (Galarza-Munoz, Gaddiel); McGrath, EL (McGrath, Erica L.); Urrabaz-Garza, R (Urrabaz-Garza, Rheanna); Gao, JL (Gao, Junling); Wu, P (Wu, Ping); Menon, R (Menon, Ramkumar); Saade, G (Saade, George); Fernandez-Salas, I (Fernandez-Salas, Ildefonso); Rossi, SL (Rossi, Shannan L.); Vasilakis, N (Vasilakis, Nikos); Routh, A (Routh, Andrew); Bradrick, SS (Bradrick, Shelton S.); Garcia-Blanco, MA (Garcia-Blanco, Mariano A.)

Source: CELL HOST & MICROBE  Volume: 20  Issue: 2  Pages: 259-270  DOI: 10.1016/j.chom.2016.07.004  Published: AUG 10 2016  

Times Cited in Web of Science Core Collection: 16

Total Times Cited: 16

Paper 16

Title: Zika virus NS1 structure reveals diversity of electrostatic surfaces among flaviviruses

Author(s): Song, H (Song, Hao); Qi, JX (Qi, Jianxun); Haywood, J (Haywood, Joel); Shi, Y (Shi, Yi); Gao, GF (Gao, George F.)

Source: NATURE STRUCTURAL & MOLECULAR BIOLOGY  Volume: 23  Issue: 5  Pages: 456-458  DOI: 10.1038/nsmb.3213  Published: MAY 2016  

Times Cited in Web of Science Core Collection: 15

Total Times Cited: 16

Paper 17

Title: Zika Virus Targets Different Primary Human Placental Cells, Suggesting Two Routes for Vertical Transmission

Author(s): Tabata, T (Tabata, Takako); Petitt, M (Petitt, Matthew); Puerta-Guardo, H (Puerta-Guardo, Henry); Michlmayr, D (Michlmayr, Daniela); Wang, C (Wang, Chunling); Fang-Hoover, J (Fang-Hoover, June); Harris, E (Harris, Eva); Pereira, L (Pereira, Lenore)

Source: CELL HOST & MICROBE  Volume: 20  Issue: 2  Pages: 155-166  DOI: 10.1016/j.chom.2016.07.002  Published: AUG 10 2016  

Times Cited in Web of Science Core Collection: 13

Total Times Cited: 13

Paper 18

Title: Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus

Author(s): Priyamvada, L (Priyamvada, Lalita); Quicke, KM (Quicke, Kendra M.); Hudson, WH (Hudson, William H.); Onlamoon, N (Onlamoon, Nattawat); Sewatanon, J (Sewatanon, Jaturong); Edupuganti, S (Edupuganti, Srilatha); Pattanapanyasat, K (Pattanapanyasat, Kovit); Chokephaibulkit, K (Chokephaibulkit, Kulkanya); Mulligan, MJ (Mulligan, Mark J.); Wilson, PC (Wilson, Patrick C.); Ahmed, R (Ahmed, Rafi); Suthar, MS (Suthar, Mehul S.); Wrammert, J (Wrammert, Jens)

Source: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA  Volume: 113  Issue: 28  Pages: 7852-7857  DOI: 10.1073/pnas.1607931113  Published: JUL 12 2016  

Times Cited in Web of Science Core Collection: 13

Total Times Cited: 13

Paper 19

Title: The Viral Polymerase Inhibitor 7-Deaza-2 '-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model

Author(s): Zmurko, J (Zmurko, Joanna); Marques, RE (Marques, Rafael E.); Schols, D (Schols, Dominique); Verbeken, E (Verbeken, Erik); Kaptein, SJF (Kaptein, Suzanne J. F.); Neyts, J (Neyts, Johan)

Source: PLOS NEGLECTED TROPICAL DISEASES  Volume: 10  Issue: 5  Article Number: e0004695  DOI: 10.1371/journal.pntd.0004695  Published: MAY 2016  

Times Cited in Web of Science Core Collection: 13

Total Times Cited: 13

Paper 20

Title: Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys

Author(s): Abbink, P (Abbink, Peter); Larocca, RA (Larocca, Rafael A.); De La Barrera, RA (De La Barrera, Rafael A.); Bricault, CA (Bricault, Christine A.); Moseley, ET (Moseley, Edward T.); Boyd, M (Boyd, Michael); Kirilova, M (Kirilova, Marinela); Li, ZF (Li, Zhenfeng); Ng'ang'a, D (Ng'ang'a, David); Nanayakkara, O (Nanayakkara, Ovini); Nityanandam, R (Nityanandam, Ramya); Mercado, NB (Mercado, Noe B.); Borducchi, EN (Borducchi, Erica N.); Agarwal, A (Agarwal, Arshi); Brinkman, AL (Brinkman, Amanda L.); Cabral, C (Cabral, Crystal); Chandrashekar, A (Chandrashekar, Abishek); Giglio, PB (Giglio, Patricia B.); Jetton, D (Jetton, David); Jimenez, J (Jimenez, Jessica); Lee, BC (Lee, Benjamin C.); Mojta, S (Mojta, Shanell); Molloy, K (Molloy, Katherine); Shetty, M (Shetty, Mayuri); Neubauer, GH (Neubauer, George H.); Stephenson, KE (Stephenson, Kathryn E.); Peron, JPS (Peron, Jean Pierre S.); Zanotto, PMD (Zanotto, Paolo M. de A.); Misamore, J (Misamore, Johnathan); Finneyfrock, B (Finneyfrock, Brad); Lewis, MG (Lewis, Mark G.); Alter, G (Alter, Galit); Modjarrad, K (Modjarrad, Kayvon); Jarman, RG (Jarman, Richard G.); Eckels, KH (Eckels, Kenneth H.); Michael, NL (Michael, Nelson L.); Thomas, SJ (Thomas, Stephen J.); Barouch, DH (Barouch, Dan H.)

Source: SCIENCE  Volume: 353  Issue: 6304  Pages: 1129-1132  DOI: 10.1126/science.aah6157  Published: SEP 9 2016  

Times Cited in Web of Science Core Collection: 12

Total Times Cited: 12

Paper 1

Title: Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains

Author(s): Hay, DA (Hay, Duncan A.); Fedorov, O (Fedorov, Oleg); Martin, S (Martin, Sarah); Singleton, DC (Singleton, Dean C.); Tallant, C (Tallant, Cynthia); Wells, C (Wells, Christopher); Picaud, S (Picaud, Sarah); Philpott, M (Philpott, Martin); Monteiro, OP (Monteiro, Octovia P.); Rogers, CM (Rogers, Catherine M.); Conway, SJ (Conway, Stuart J.); Rooney, TPC (Rooney, Timothy P. C.); Tumber, A (Tumber, Anthony); Yapp, C (Yapp, Clarence); Filippakopoulos, P (Filippakopoulos, Panagis); Bunnage, ME (Bunnage, Mark E.); Muller, S (Mueller, Susanne); Knapp, S (Knapp, Stefan); Schofield, CJ (Schofield, Christopher J.); Brennan, PE (Brennan, Paul E.)

Source: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY  Volume: 136  Issue: 26  Pages: 9308-9319  DOI: 10.1021/ja412434f  Published: JUL 2 2014  

Times Cited in Web of Science Core Collection: 69

Total Times Cited: 69

Paper 2

Title: Small Molecule Inhibitors of Bromodomain-Acetyl-lysine Interactions

Author(s): Brand, M (Brand, Michael); Measures, AM (Measures, Angelina M.); Wilson, BG (Wilson, Brian G.); Cortopassi, WA (Cortopassi, Wilian A.); Alexander, R (Alexander, Rikki); Hoss, M (Hoess, Matthias); Hewings, DS (Hewings, David S.); Rooney, TPC (Rooney, Timothy P. C.); Paton, RS (Paton, Robert S.); Conway, SJ (Conway, Stuart J.)

Source: ACS CHEMICAL BIOLOGY  Volume: 10  Issue: 1  Pages: 22-39  DOI: 10.1021/cb500996u  Published: JAN 2015  

Times Cited in Web of Science Core Collection: 42

Total Times Cited: 42

Paper 3

Title: LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor

Author(s): Clark, PGK (Clark, Peter G. K.); Vieira, LCC (Vieira, Lucas C. C.); Tallant, C (Tallant, Cynthia); Fedorov, O (Fedorov, Oleg); Singleton, DC (Singleton, Dean C.); Rogers, CM (Rogers, Catherine M.); Monteiro, OP (Monteiro, Octovia P.); Bennett, JM (Bennett, James M.); Baronio, R (Baronio, Roberta); Muller, S (Mueller, Susanne); Daniels, DL (Daniels, Danette L.); Mendez, J (Mendez, Jacqui); Knapp, S (Knapp, Stefan); Brennan, PE (Brennan, Paul E.); Dixon, DJ (Dixon, Darren J.)

Source: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION  Volume: 54  Issue: 21  Pages: 6217-6221  DOI: 10.1002/anie.201501394  Published: MAY 18 2015  

Times Cited in Web of Science Core Collection: 37

Total Times Cited: 38

Paper 4

Title: Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition

Author(s): Theodoulou, NH (Theodoulou, Natalie H.); Bamborough, P (Bamborough, Paul); Bannister, AJ (Bannister, Andrew J.); Becher, I (Becher, Isabelle); Bit, RA (Bit, Rino A.); Che, KH (Che, Ka Hing); Chung, CW (Chung, Chun-wa); Dittmann, A (Dittmann, Antje); Drewes, G (Drewes, Gerard); Drewry, DH (Drewry, David H.); Gordon, L (Gordon, Laurie); Grandi, P (Grandi, Paola); Leveridge, M (Leveridge, Melanie); Lindon, M (Lindon, Matthew); Michon, AM (Michon, Anne-Marie); Molnar, J (Molnar, Judit); Robson, SC (Robson, Samuel C.); Tomkinson, NCO (Tomkinson, Nicholas C. O.); Kouzarides, T (Kouzarides, Tony); Prinjha, RK (Prinjha, Rab K.); Humphreys, PG (Humphreys, Philip G.)

Source: JOURNAL OF MEDICINAL CHEMISTRY  Volume: 59  Issue: 4  Special Issue: SI  Pages: 1425-1439  DOI: 10.1021/acs.jmedchem.5b00256  Published: FEB 25 2016  

Times Cited in Web of Science Core Collection: 26

Total Times Cited: 26

Paper 5

Title: Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B

Author(s): Chen, PL (Chen, Peiling); Chaikuad, A (Chaikuad, Apirat); Bamborough, P (Bamborough, Paul); Bantscheff, M (Bantscheff, Marcus); Bountra, C (Bountra, Chas); Chung, CW (Chung, Chun-wa); Fedorov, O (Fedorov, Oleg); Grandi, P (Grandi, Paola); Jung, D (Jung, David); Lesniak, R (Lesniak, Robert); Lindon, M (Lindon, Matthew); Muller, S (Mueller, Susanne); Philpott, M (Philpott, Martin); Prinjha, R (Prinjha, Rab); Rogers, C (Rogers, Catherine); Selenski, C (Selenski, Carolyn); Tallant, C (Tallant, Cynthia); Werner, T (Werner, Thilo); Willson, TM (Willson, Timothy M.); Knapp, S (Knapp, Stefan); Drewry, DH (Drewry, David H.)

Source: JOURNAL OF MEDICINAL CHEMISTRY  Volume: 59  Issue: 4  Special Issue: SI  Pages: 1410-1424  DOI: 10.1021/acs.jmedchem.5b00209  Published: FEB 25 2016  

Times Cited in Web of Science Core Collection: 25

Total Times Cited: 25

Paper 6

Title: The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNFMutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies

Author(s): Vangamudi, B (Vangamudi, Bhavatarini); Paul, TA (Paul, Thomas A.); Shah, PK (Shah, Parantu K.); Kost-Alimova, M (Kost-Alimova, Maria); Nottebaum, L (Nottebaum, Lisa); Shi, X (Shi, Xi); Zhan, YA (Zhan, Yanai); Leo, E (Leo, Elisabetta); Mahadeshwar, HS (Mahadeshwar, Harshad S.); Protopopov, A (Protopopov, Alexei); Futreal, A (Futreal, Andrew); Tieu, TN (Tieu, Trang N.); Peoples, M (Peoples, Mike); Heffernan, TP (Heffernan, Timothy P.); Marszalek, JR (Marszalek, Joseph R.); Toniatti, C (Toniatti, Carlo); Petrocchi, A (Petrocchi, Alessia); Verhelle, D (Verhelle, Dominique); Owen, DR (Owen, Dafydd R.); Draetta, G (Draetta, Giulio); Jones, P (Jones, Philip); Palmer, WS (Palmer, Wylie S.); Sharma, S (Sharma, Shikhar); Andersen, JN (Andersen, Jannik N.)

Source: CANCER RESEARCH  Volume: 75  Issue: 18  Pages: 3865-3878  DOI: 10.1158/0008-5472.CAN-14-3798  Published: SEP 15 2015  

Times Cited in Web of Science Core Collection: 23

Total Times Cited: 23

Paper 7

Title: Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF

Author(s): Bennett, J (Bennett, James); Fedorov, O (Fedorov, Oleg); Tallant, C (Tallant, Cynthia); Monteiro, O (Monteiro, Octovia); Meier, J (Meier, Julia); Gamble, V (Gamble, Vicky); Savitsky, P (Savitsky, Pavel); Nunez-Alonso, GA (Nunez-Alonso, Graciela A.); Haendler, B (Haendler, Bernard); Rogers, C (Rogers, Catherine); Brennan, PE (Brennan, Paul E.); Muller, S (Mueller, Susanne); Knapp, S (Knapp, Stefan)

Source: JOURNAL OF MEDICINAL CHEMISTRY  Volume: 59  Issue: 4  Special Issue: SI  Pages: 1642-1647  DOI: 10.1021/acs.jmedchem.5b00458  Published: FEB 25 2016  

Times Cited in Web of Science Core Collection: 22

Total Times Cited: 22

Paper 8

Title: Disrupting Acetyl-Lysine Recognition: Progress in the Development of Bromodomain Inhibitors

Author(s): Romero, FA (Romero, F. Anthony); Taylor, AM (Taylor, Alexander M.); Crawford, TD (Crawford, Terry D.); Tsui, V (Tsui, Vickie); Cote, A (Cote, Alexandre); Magnuson, S (Magnuson, Steven)

Source: JOURNAL OF MEDICINAL CHEMISTRY  Volume: 59  Issue: 4  Special Issue: SI  Pages: 1271-1298  DOI: 10.1021/acs.jmedchem.5b01514  Published: FEB 25 2016  

Times Cited in Web of Science Core Collection: 21

Total Times Cited: 21

Paper 9

Title: Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor

Author(s): Palmer, WS (Palmer, Wylie S.); Poncet-Montange, G (Poncet-Montange, Guillaume); Liu, G (Liu, Gang); Petrocchi, A (Petrocchi, Alessia); Reyna, N (Reyna, Naphtali); Subramanian, G (Subramanian, Govindan); Theroff, J (Theroff, Jay); Yau, A (Yau, Anne); Kost-Alimova, M (Kost-Alimova, Maria); Bardenhagen, JP (Bardenhagen, Jennifer P.); Leo, E (Leo, Elisabetta); Shepard, HE (Shepard, Hannah E.); Tieu, TN (Tieu, Trang N.); Shi, X (Shi, Xi); Zhao, YN (Zhao, Yanai); Zhao, SP (Zhao, Shuping); Barton, MC (Barton, Michelle C.); Draetta, G (Draetta, Giulio); Toniatti, C (Toniatti, Carlo); Jones, P (Jones, Philip); Do, MG (Do, Mary Geck); Andersen, JN (Andersen, Jannik N.)

Source: JOURNAL OF MEDICINAL CHEMISTRY  Volume: 59  Issue: 4  Special Issue: SI  Pages: 1440-1454  DOI: 10.1021/acs.jmedchem.5b00405  Published: FEB 25 2016  

Times Cited in Web of Science Core Collection: 17

Total Times Cited: 18

Paper 10

Title: Fragment-Based Design of Selective Nanomolar Ligands of the CREBBP Bromodomain

Author(s): Unzue, A (Unzue, Andrea); Xu, M (Xu, Min); Dong, J (Dong, Jing); Wiedmer, L (Wiedmer, Lars); Spiliotopoulos, D (Spiliotopoulos, Dimitrios); Caflisch, A (Caflisch, Amedeo); Nevado, C (Nevado, Cristina)

Source: JOURNAL OF MEDICINAL CHEMISTRY  Volume: 59  Issue: 4  Special Issue: SI  Pages: 1350-1356  DOI: 10.1021/acs.jmedchem.5b00172  Published: FEB 25 2016  

Times Cited in Web of Science Core Collection: 13

Total Times Cited: 13

Paper 11

Title: Discovery of CREBBP Bromodomain Inhibitors by High-Throughput Docking and Hit Optimization Guided by Molecular Dynamics

Author(s): Xu, M (Xu, Min); Unzue, A (Unzue, Andrea); Dong, J (Dong, Jing); Spiliotopoulos, D (Spiliotopoulos, Dimitrios); Nevado, C (Nevado, Cristina); Caflisch, A (Caflisch, Amedeo)

Source: JOURNAL OF MEDICINAL CHEMISTRY  Volume: 59  Issue: 4  Special Issue: SI  Pages: 1340-1349  DOI: 10.1021/acs.jmedchem.5b00171  Published: FEB 25 2016  

Times Cited in Web of Science Core Collection: 13

Total Times Cited: 13

Paper 12

Title: Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

Author(s): Martin, LJ (Martin, Laetitia J.); Koegl, M (Koegl, Manfred); Bader, G (Bader, Gerd); Cockcroft, XL (Cockcroft, Xiao-Ling); Fedorov, O (Fedorov, Oleg); Fiegen, D (Fiegen, Dennis); Gerstberger, T (Gerstberger, Thomas); Hofmann, MH (Hofmann, Marco H.); Hohmann, AF (Hohmann, Anja F.); Kessler, D (Kessler, Dirk); Knapp, S (Knapp, Stefan); Knesl, P (Knesl, Petr); Kornigg, S (Kornigg, Stefan); Muller, S (Muller, Susanne); Nar, H (Nar, Herbert); Rogers, C (Rogers, Catherine); Rumpel, K (Rumpel, Klaus); Schaaf, O (Schaaf, Otmar); Steurer, S (Steurer, Steffen); Tallan, C (Tallan, Cynthia); Vakoc, CR (Vakoc, Christopher R.); Zeeb, M (Zeeb, Markus); Zoephel, A (Zoephel, Andreas); Pearson, M (Pearson, Mark); Boehmelt, G (Boehmelt, Guido); McConnell, D (McConnell, Darryl)

Source: JOURNAL OF MEDICINAL CHEMISTRY  Volume: 59  Issue: 10  Pages: 4462-4475  DOI: 10.1021/acs.jmedchem.5b01865  Published: MAY 26 2016  

Times Cited in Web of Science Core Collection: 11

Total Times Cited: 11

Paper 1

Title: Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer

Author(s): Eruslanov, EB (Eruslanov, Evgeniy B.); Bhojnagarwala, PS (Bhojnagarwala, Pratik S.); Quatromoni, JG (Quatromoni, Jon G.); Stephen, TL (Stephen, Tom Li); Ranganathan, A (Ranganathan, Anjana); Deshpande, C (Deshpande, Charuhas); Akimova, T (Akimova, Tatiana); Vachani, A (Vachani, Anil); Litzky, L (Litzky, Leslie); Hancock, WW (Hancock, Wayne W.); Conejo-Garcia, JR (Conejo-Garcia, Jose R.); Feldman, M (Feldman, Michael); Albeida, SM (Albeida, Steven M.); Singhal, S (Singhal, Sunil)

Source: JOURNAL OF CLINICAL INVESTIGATION  Volume: 124  Issue: 12  Pages: 5466-5480  DOI: 10.1172/JCI7053  Published: DEC 2014  

Times Cited in Web of Science Core Collection: 63

Total Times Cited: 64

Paper 2

Title: Neutrophils support lung colonization of metastasis-initiating breast cancer cells

Author(s): Wculek, SK (Wculek, Stefanie K.); Malanchi, I (Malanchi, Ilaria)

Source: NATURE  Volume: 528  Issue: 7582  Pages: 413-+  DOI: 10.1038/nature16140  Published: DEC 17 2015  

Times Cited in Web of Science Core Collection: 48

Total Times Cited: 50

Paper 3

Title: Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils

Author(s): Casbon, AJ (Casbon, Amy-Jo); Reynaud, D (Reynaud, Damien); Park, C (Park, Chanhyuk); Khuc, E (Khuc, Emily); Gan, DD (Gan, Dennis D.); Schepers, K (Schepers, Koen); Passegue, E (Passegue, Emmanuelle); Werb, Z (Werb, Zena)

Source: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA  Volume: 112  Issue: 6  Pages: E566-E575  DOI: 10.1073/pnas.1424927112  Published: FEB 10 2015  

Times Cited in Web of Science Core Collection: 36

Total Times Cited: 36

Paper 4

Title: MET is required for the recruitment of anti-tumoural neutrophils

Author(s): Finisguerra, V (Finisguerra, Veronica); Di Conza, G (Di Conza, Giusy); Di Matteo, M (Di Matteo, Mario); Serneels, J (Serneels, Jens); Costa, S (Costa, Sandra); Thompson, AAR (Thompson, A. A. Roger); Wauters, E (Wauters, Els); Walmsley, S (Walmsley, Sarah); Prenen, H (Prenen, Hans); Granot, Z (Granot, Zvi); Casazza, A (Casazza, Andrea); Mazzone, M (Mazzone, Massimiliano)

Source: NATURE  Volume: 522  Issue: 7556  Pages: 349-+  DOI: 10.1038/nature14407  Published: JUN 18 2015  

Times Cited in Web of Science Core Collection: 34

Total Times Cited: 34

Paper 5

Title: Toward harmonized phenotyping of human myeloid-derived suppressor cells by flow cytometry: results from an interim study

Author(s): Mandruzzato, S (Mandruzzato, Susanna); Brandau, S (Brandau, Sven); Britten, CM (Britten, Cedrik M.); Bronte, V (Bronte, Vincenzo); Damuzzo, V (Damuzzo, Vera); Gouttefangeas, C (Gouttefangeas, Cecile); Maurer, D (Maurer, Dominik); Ottensmeier, C (Ottensmeier, Christian); van der Burg, SH (van der Burg, Sjoerd H.); Welters, MJP (Welters, Marij J. P.); Walter, S (Walter, Steffen)

Source: CANCER IMMUNOLOGY IMMUNOTHERAPY  Volume: 65  Issue: 2  Pages: 161-169  DOI: 10.1007/s00262-015-1782-5  Published: FEB 2016  

Times Cited in Web of Science Core Collection: 16

Total Times Cited: 16

Paper 6

Title: Neutrophils in the Tumor Microenvironment

Author(s): Powell, DR (Powell, Davalyn R.); Huttenlocher, A (Huttenlocher, Anna)

Source: TRENDS IN IMMUNOLOGY  Volume: 37  Issue: 1  Pages: 41-52  DOI: 10.1016/j.it.2015.11.008  Published: JAN 2016  

Times Cited in Web of Science Core Collection: 14

Total Times Cited: 14

Paper 7

Title: Type I IFNs induce anti-tumor polarization of tumor associated neutrophils in mice and human

Author(s): Andzinski, L (Andzinski, Lisa); Kasnitz, N (Kasnitz, Nadine); Stahnke, S (Stahnke, Stephanie); Wu, CF (Wu, Ching-Fang); Gereke, M (Gereke, Marcus); von Kockritz-Blickwede, M (von Koeckritz-Blickwede, Maren); Schilling, B (Schilling, Bastian); Brandau, S (Brandau, Sven); Weiss, S (Weiss, Siegfried); Jablonska, J (Jablonska, Jadwiga)

Source: INTERNATIONAL JOURNAL OF CANCER  Volume: 138  Issue: 8  Pages: 1982-1993  DOI: 10.1002/ijc.29945  Published: APR 15 2016  

Times Cited in Web of Science Core Collection: 13

Total Times Cited: 14

Paper 8

Title: The Complex Role of Neutrophils in Tumor Angiogenesis and Metastasis

Author(s): Liang, W (Liang, Wei); Ferrara, N (Ferrara, Napoleone)

Source: CANCER IMMUNOLOGY RESEARCH  Volume: 4  Issue: 2  Pages: 83-91  DOI: 10.1158/2326-6066.CIR-15-0313  Published: FEB 2016  

Times Cited in Web of Science Core Collection: 13

Total Times Cited: 14

Paper 9

Title: Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells

Author(s): Spiegel, A (Spiegel, Asaf); Brooks, MW (Brooks, Mary W.); Houshyar, S (Houshyar, Samin); Reinhardt, F (Reinhardt, Ferenc); Ardolino, M (Ardolino, Michele); Fessler, E (Fessler, Evelyn); Chen, MB (Chen, Michelle B.); Krall, JA (Krall, Jordan A.); DeCock, J (DeCock, Jasmine); Zervantonakis, IK (Zervantonakis, Ioannis K.); Iannello, A (Iannello, Alexandre); Iwamoto, Y (Iwamoto, Yoshiko); Cortez-Retamozo, V (Cortez-Retamozo, Virna); Kamm, RD (Kamm, Roger D.); Pittet, MJ (Pittet, Mikael J.); Raulet, DH (Raulet, David H.); Weinberg, RA (Weinberg, Robert A.)

Source: CANCER DISCOVERY  Volume: 6  Issue: 6  Pages: 630-649  DOI: 10.1158/2159-8290.CD-15-1157  Published: JUN 2016  

Times Cited in Web of Science Core Collection: 10

Total Times Cited: 10

Paper 1

Title: Persistence of Ebola Virus in Ocular Fluid during Convalescence

Author(s): Varkey, JB (Varkey, Jay B.); Shantha, JG (Shantha, Jessica G.); Crozier, I (Crozier, Ian); Kraft, CS (Kraft, Colleen S.); Lyon, GM (Lyon, G. Marshall); Mehta, AK (Mehta, Aneesh K.); Kumar, G (Kumar, Gokul); Smith, JR (Smith, Justine R.); Kainulainen, MH (Kainulainen, Markus H.); Whitmer, S (Whitmer, Shannon); Stroher, U (Stroeher, Ute); Uyeki, TM (Uyeki, Timothy M.); Ribner, BS (Ribner, Bruce S.); Yeh, S (Yeh, Steven)

Source: NEW ENGLAND JOURNAL OF MEDICINE  Volume: 372  Issue: 25  Pages: 2423-2427  DOI: 10.1056/NEJMoa1500306  Published: JUN 18 2015  

Times Cited in Web of Science Core Collection: 94

Total Times Cited: 94

Paper 2

Title: Molecular Evidence of Sexual Transmission of Ebola Virus

Author(s): Mate, SE (Mate, S. E.); Kugelman, JR (Kugelman, J. R.); Nyenswah, TG (Nyenswah, T. G.); Ladner, JT (Ladner, J. T.); Wiley, MR (Wiley, M. R.); Cordier-Lassalle, T (Cordier-Lassalle, T.); Christie, A (Christie, A.); Schroth, GP (Schroth, G. P.); Gross, SM (Gross, S. M.); Davies-Wayne, GJ (Davies-Wayne, G. J.); Shinde, SA (Shinde, S. A.); Murugan, R (Murugan, R.); Sieh, SB (Sieh, S. B.); Badio, M (Badio, M.); Fakoli, L (Fakoli, L.); Taweh, F (Taweh, F.); de Wit, E (de Wit, E.); van Doremalen, N (van Doremalen, N.); Munster, VJ (Munster, V. J.); Pettitt, J (Pettitt, J.); Prieto, K (Prieto, K.); Humrighouse, BW (Humrighouse, B. W.); Stroher, U (Stroeher, U.); DiClaro, JW (DiClaro, J. W.); Hensley, LE (Hensley, L. E.); Schoepp, RJ (Schoepp, R. J.); Safronetz, D (Safronetz, D.); Fair, J (Fair, J.); Kuhn, JH (Kuhn, J. H.); Blackley, DJ (Blackley, D. J.); Laney, AS (Laney, A. S.); Williams, DE (Williams, D. E.); Lo, T (Lo, T.); Gasasira, A (Gasasira, A.); Nichol, ST (Nichol, S. T.); Formenty, P (Formenty, P.); Kateh, FN (Kateh, F. N.); De Cock, KM (De Cock, K. M.); Bolay, F (Bolay, F.); Sanchez-Lockhart, M (Sanchez-Lockhart, M.); Palacios, G (Palacios, G.)

Source: NEW ENGLAND JOURNAL OF MEDICINE  Volume: 373  Issue: 25  Pages: 2448-2454  DOI: 10.1056/NEJMoa1509773  Published: DEC 17 2015  

Times Cited in Web of Science Core Collection: 60

Total Times Cited: 61

Paper 3

Title: Possible Sexual Transmission of Ebola Virus - Liberia, 2015

Author(s): Christie, A (Christie, Athalia); Davies-Wayne, GJ (Davies-Wayne, Gloria J.); Cordier-Lasalle, T (Cordier-Lasalle, Thierry); Blackley, DJ (Blackley, David J.); Laney, AS (Laney, A. Scott); Williams, DE (Williams, Desmond E.); Shinde, SA (Shinde, Shivam A.); Badio, M (Badio, Moses); Lo, T (Lo, Terrence); Mate, SE (Mate, Suzanne E.); Ladner, JT (Ladner, Jason T.); Wiley, MR (Wiley, Michael R.); Kugelman, JR (Kugelman, Jeffrey R.); Palacios, G (Palacios, Gustavo); Holbrook, MR (Holbrook, Michael R.); Janosko, KB (Janosko, Krisztina B.); de Wit, E (de Wit, Emmie); van Doremalen, N (van Doremalen, Neeltje); Munster, VJ (Munster, Vincent J.); Pettitt, J (Pettitt, James); Schoepp, RJ (Schoepp, Randal J.); Verhenne, L (Verhenne, Leen); Evlampidou, I (Evlampidou, Iro); Kollie, KK (Kollie, Karsor K.); Sieh, SB (Sieh, Sonpon B.); Gasasira, A (Gasasira, Alex); Bolay, F (Bolay, Fatorma); Kateh, FN (Kateh, Francis N.); Nyenswah, TG (Nyenswah, Tolbert G.); De Cock, KM (De Cock, Kevin M.)

Source: MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT  Volume: 64  Issue: 17  Pages: 479-481  Published: MAY 8 2015  

Times Cited in Web of Science Core Collection: 53

Total Times Cited: 55

Paper 4

Title: Long-term sequelae after Ebola virus disease in Bundibugyo, Uganda: a retrospective cohort study

Author(s): Clark, DV (Clark, Danielle V.); Kibuuka, H (Kibuuka, Hannah); Millard, M (Millard, Monica); Wakabi, S (Wakabi, Salim); Lukwago, L (Lukwago, Luswa); Taylor, A (Taylor, Alison); Eller, MA (Eller, Michael A.); Eller, LA (Eller, Leigh Anne); Michael, NL (Michael, Nelson L.); Honko, AN (Honko, Anna N.); Olinger, GG (Olinger, Gene G., Jr.); Schoepp, RJ (Schoepp, Randal J.); Hepburn, MJ (Hepburn, Matthew J.); Hensley, LE (Hensley, Lisa E.); Robb, ML (Robb, Merlin L.)

Source: LANCET INFECTIOUS DISEASES  Volume: 15  Issue: 8  Pages: 905-912  DOI: 10.1016/S1473-3099(15)70152-0  Published: AUG 2015  

Times Cited in Web of Science Core Collection: 42

Total Times Cited: 42

Paper 5

Title: Early clinical sequelae of Ebola virus disease in Sierra Leone: a cross-sectional study

Author(s): Mattia, JG (Mattia, John G.); Vandy, MJ (Vandy, Mathew J.); Chang, JC (Chang, Joyce C.); Platt, DE (Platt, Devin E.); Dierberg, K (Dierberg, Kerry); Bausch, DG (Bausch, Daniel G.); Brooks, T (Brooks, Tim); Conteh, S (Conteh, Sampha); Crozier, I (Crozier, Ian); Fowler, RA (Fowler, Robert A.); Kamara, AP (Kamara, Amadu P.); Kang, C (Kang, Cindy); Mahadevan, S (Mahadevan, Srividya); Mansaray, Y (Mansaray, Yealie); Marcell, L (Marcell, Lauren); McKay, G (McKay, Gillian); O'Dempsey, T (O'Dempsey, Tim); Parris, V (Parris, Victoria); Pinto, R (Pinto, Ruxandra); Rangel, A (Rangel, Audrey); Salam, AP (Salam, Alex P.); Shantha, J (Shantha, Jessica); Wolfman, V (Wolfman, Vanessa); Yeh, S (Yeh, Steven); Chan, AK (Chan, Adrienne K.); Mishra, S (Mishra, Sharmistha)

Source: LANCET INFECTIOUS DISEASES  Volume: 16  Issue: 3  Pages: 331-338  DOI: 10.1016/S1473-3099(15)00489-2  Published: MAR 2016  

Times Cited in Web of Science Core Collection: 20

Total Times Cited: 20

Paper 6

Title: Systematic review of the literature on viral persistence and sexual transmission from recovered Ebola survivors: evidence and recommendations

Author(s): Thorson, A (Thorson, Anna); Formenty, P (Formenty, Pierre); Lofthouse, C (Lofthouse, Clare); Broutet, N (Broutet, Nathalie)

Source: BMJ OPEN  Volume: 6  Issue: 1  Article Number: e008859  DOI: 10.1136/bmjopen-2015-008859  Published: 2016  

Times Cited in Web of Science Core Collection: 10

Total Times Cited: 10