Genetic Aspects of Tuberculosis in the Lung

The aim of this request for applications is to stimulate research on the genetic aspects of tuberculosis, exploiting advances in molecular biology and genomics research. It is important to learn about the interaction between host and microbial genes and to identify genes, or families of genes that determine virulence, latency, reactivation of disease or resistance to antituberculous drugs. Areas of particular interest are studies using novel biotechnologies, such as microarrays, molecular beacon technology, or differential signature-tagged mutagenesis (DSTM) and innovative collaborations with computational biologists to identify genes that mediate the pathogenesis of tuberculosis and elucidate the mechanisms that are responsible. Letter of intent deadline: November 1; application deadline: January 17, 2001.
Contact: Hannah Peavy
Address: Division of Lung Diseases, National Heart Lung and Blood Institute, 6701 Rockledge Drive, Suite 10018, MSC 7952, Bethesda, MD 20892-7952, USA
Telephone: (301) 435 0222 Fax: (301) 480 3557
Email: peavyh@nih.gov