Post Doctoral Research Fellow in Department of Applied Sciences, Translational Bioscience

Newcastle Upon Tyne, Tyne and Wear (GB)
05 Nov 2023
15 Dec 2023
Life sciences, Biological Sciences
Fixed Term
Full Time


The Johnson Laboratory in the Department of Applied Sciences, Translational Bioscience, at Northumbria University is seeking a Postdoc to join our team in studying the mechanisms underlying immune activation and disease progression in genetic mitochondrial disorders. Expertise in biology (cell, molecular, pathology) is an essential requirement of this position, a background in mitochondrial disease and/or immunology is preferred. Experience with cell culture is highly preferred. Ideal candidates should be motivated, organised, and able to work independently. The selected candidate will contribute to setting project goals, designing experiments, generating and analysing data, preparing manuscripts, and preparing and submitting funding applications. They will collaborate with others within the Johnson laboratory as well as with colleagues at Northumbria University, Newcastle University, and beyond. They will be required to demonstrate scientific integrity and safe laboratory practices.

Duties Include:

  • Conceiving and executing disease biology focused research to achieve project and program goals.
  • Performing routine and complex laboratory procedures. Developing, adapting, and implementing new research techniques and protocols.
  • Collecting and interpreting data, and assisting in preparation of manuscripts and grant proposals. 
  • Being responsible for designing experiments and assembling data for publications and presentations as author or co-author.
  • Critically evaluating relevant scientific advances and integrating this knowledge into research programs. 
  • Maintaining a high level of productivity in the laboratory setting.
  • Resolving key project hurdles as they arise by utilising available information and technical expertise, and discussing and planning with Dr Johnson, as well as with relevant collaborators.
  • As relevant, presenting work in scientific venues such as local conferences. 
  • Proactively seeking out new information in the literature and incorporate this into individual project(s) as well as the overall program. 
  • Writing and/or communicating relevant regulatory materials such as project safety documents.

For further detail see the job description. 

This is a fixed term role for 3 years.


You will be joining the Johnson laboratory ( at Northumbria University. Our research team studies the role of mitochondria in biology and disease, with a particular focus on genetic mitochondrial diseases. Our group recently relocated from Seattle, Washington, USA to Northumbria University. Our mouse colony is housed at Newcastle University. Our laboratory is well equipped and well connected. Our work has led to multiple international awards in translational medicine and mitochondrial research, and we are pursuing an extremely exciting area of study probing the mechanisms that lead to immune activation and recruitment in genetic mitochondrial disease. The project you will be joining has been funded by a prestigious Academy of Medical Sciences professorship, and follows up on exciting new leads using novel techniques. We are ideally situated in Newcastle upon Tyne, home to a number of mitochondrial disease experts. Dr Johnson has mentored dozens of successful students and multiple postdoctoral researchers.


The role holder should have:

  • Doctoral degree in Biology (Cell, molecular, cancer, immunology) or a related discipline
  • Strong background and training in cell and molecular biology sciences and experimental techniques
  • Experience in designing  experiments to probe disease mechanism.
  • Experience in performing cell culture; ideally experience in FACS, Immunoblotting, Immunofluorescence, Molecular cloning strategies, PCR and other molecular biology techniques
  • The ability to interact with an interdisciplinary group including disease area biologists, chemists, data analysts, laboratory biologists, and computer scientists
  • Ability to prioritise multiple tasks at one time
  • Ability to work independently and as part of a team
  • Must be proficient with computers, relevant non-specialty software (Microsoft office suite, etc), and scientific software (GraphPad Prism or similar statistical software; Endnote or similar; etc).
  • Most importantly, a willingness to learn where any of these qualifications are lacking.

For further information about the role please see the person specification.

If you would like an informal discussion about the role, please contact Professor Simon Johnson (

To apply for this vacancy please click 'Apply Now'.  Your application should include a covering letter and a CV.


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