Research Specialist B/C - School of Medicine

Location
Pennsylvania (US)
Posted
17 Aug 2018
End of advertisement period
17 Oct 2018
Ref
40-29607
Contract Type
Fixed Term
Hours
Full Time

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

The Perelman School of Medicine at the University of Pennsylvania is the oldest and one of the finest medical schools in the United States. Penn is rich in tradition and heritage and at the same time consistently at the forefront of new developments and innovations in medical education and research. Since its founding in 1765 the School has been a strong presence in the community and prides itself on educating the leaders of tomorrow in patient care, biomedical research, and medical education. http://www.med.upenn.edu/

The Research Specialist will be responsible for generating genome edited hESC/hiPSC lines using CRISPR/Cas9 and other emerging gene editing technology for Core facility users. He/she will design, construct and validate all vectors required for each gene editing project; and generate and characterize edited cell lines to be delivered to Core users. The Specialist will interact frequently with Core users to discuss and present project progress in order to achieve project milestones in a timely manner. This position will also serve as the iPSC Core lab manager and order laboratory supplies.

Research Specialist B

Under limited supervision, designs, performs routine to moderately complex laboratory experiments related to assigned research projects, analyzes data and prepares data reports; keeps accurate and detailed lab notebooks; interacts with Core users for data reporting; provides assistance in the preparation of publications and presentations. He or she will also serve as the iPSC Core lab manager and orders laboratory supplies.

Research Specialist C 

In addition to performing all the duties for Research Specialist B, he or she will also assume more responsibility and independence in managing assigned research projects, establish and troubleshoot new protocols related to genome editing. He/she will also keep abreast with emerging genome editing literature.

Research Specialist B: The ideal candidate must hold the minimum of a Bachelor’s degree in the biological sciences or equivalent with at least 1 year to 3 years of experience or an equivalent combination of education and experience required. Relevant hands-on wet laboratory experience outside of the classroom preferred.

Research Specialist C: The ideal candidate must hold the minimum of a Bachelor’s degree in the biological sciences or equivalent with at least 3 years to 5 years of experience or an equivalent combination of education and experience required. Advanced degree is highly desirable. Relevant hands-on wet laboratory experience outside of the classroom preferred.

Both: 

The successful candidate must have a solid background in molecular biology techniques including restriction enzyme digestion, PCR, qRT-PCR and be proficient in DNA analysis software tools for PCR primer design and manipulation of DNA sequences. Experience with CRISPR/Cas9 gene editing in cell lines or animals is highly desirable. He/she should have hands-on experience in mammalian cell culture. Experience with hESC/hiPSC culture is highly desirable but not required. Experience with Fluorescence Activated Cell Sorting (FACS) is preferred. He/she should have excellent written and verbal communications skills, strong organizational skills and familiarity with computer software including Microsoft Office and Photoshop. 

Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.