Research Scientist in J&J Lung Cancer Initiative Collaboration

Massachusetts, United States
17 Sep 2018
End of advertisement period
17 Nov 2018
Contract Type
Full Time

Koch Institute (KI) for Integrative Cancer Research-J&J Lung Cancer Initiative Collaboration (multiple positions), to contribute to three KI laboratories involved in research regarding the discovery and development of therapeutics and diagnostics that may be useful treating, preventing, intercepting, and/or diagnosing diseases specifically focused on lung cancer.

The Jacks Laboratory will focus on genetic and epigenetic changes accompanying and controlling lung cancer initiation and progression; developing vaccines for disease interception; and the role of inflammation, inflammatory cells, and specific inflammatory mediators in lung cancer development.

The Bhatia Laboratory will focus on novel diagnostic and early detection technologies for lung cancer, including protease activity-based nanosensors and explore the utility of aerosol delivery of pro diagnostic agents to the lung and urinary paper diagnostics in mouse models of lung cancer, with the goal of detecting and stratifying disease early enough for interception.

The Irvine laboratory will focus on early interception using immunotherapy agents to detect and prophylactically protect from lung cancer and generate novel immune-based drugs and vaccine platforms, especially focused on Kras-mutant lung tumors. These will be tested initially in GEMM models. Will contribute to executing research aims; establishing research strategy; reporting; and planning and writing animal and other protocols, manuscripts, and reports.

Job Requirements

REQUIRED: MD and/or Ph.D. in medicine and/or biomedical science; extensive knowledge of cancer biology and related fields; ability to conceptualize and write proposals and publishable manuscripts, evaluate and train junior researchers, innovate, and conduct research; meticulous attention to detail; strong organizational, documentation, interpersonal, and communication skills; comfort summarizing and reporting results; ability to work collaboratively, follow safety procedures, and maintain a safe work environment.  Familiarity with physiology; cell and molecular biology; immunology; animal testing of biologics; materials science; and/or histological, biochemical, and mechanical analyses ideal.  Job #15547

This is a one-year, term-limit appointment with an extension based on continued funding. 

MIT is an equal employment opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, sex, sexual orientation, gender identity, religion, disability, age, genetic information, veteran status, ancestry, or national or ethnic origin.