UNIVERSITY OF EXETER

Postdoctoral Research Associate/Fellow - College of Engineering, Mathematics and Physical Sciences

Location
Exeter, Devon (GB)
Posted
19 Feb 2018
End of advertisement period
18 Mar 2018
Contract Type
Fixed Term
Hours
Full Time

Job title: Postdoctoral Research Associate/Fellow 

Our reference number: P61699

Salaries: Postdoctoral Research Associate: Salary from £26,495 up to £29,799 on Grade E, depending on qualifications and experience. Postdoctoral Research Fellow: Salary from £34,520 up to £38,833 on Grade F, depending on qualifications and experience.

EPSRC Healthcare Technologies Raman Nanotheranostics (RaNT) Programme

College of Engineering, Mathematics and Physical Sciences

We are recruiting three Postdoctoral Research Associates/Fellows, based in Exeter, to participate in a substantial multi-disciplinary programme.  These full time EPSRC funded posts are available from 1st April 2018 on a fixed-term basis for 36 months.  The posts will be part of a team of leading scientists working to develop engineering and physical science solutions to solve the clinical needs in patient specific diagnosis and effective treatment of cancers. 

The posts 

The EPSRC have funded the University of Exeter, University of Cambridge, London School of Pharmacy (UCL) and the STFC Rutherford Appleton Laboratory to undertake a substantial multi-disciplinary programme of work exploring Raman NanoTheranostics (RaNT). 

We propose to develop a new clinical platform technology that combines optical multiplexed disease detection with specific therapeutic selection and monitoring. We will develop innovative nanoparticle (NP) constructs, uniquely safe to the body, coupled with novel readout technologies, capable of detecting signals from depths of >8 cm non-invasively, mediating targeted therapies with light and non-invasively monitoring the efficacy of these and other therapies. This will address a critical clinical need of the provision of accurate and early disease diagnosis accompanied by effective, patient and disease specific therapy.

Specifically, we seek three postdoctoral research scientists each with a different but complementary role and required skill set:

1)    To focus on the development of surface enhanced spatially offset Raman spectroscopy (SESORS) from a proof of concept to a multiplexed deep tissue imaging tool, able to non-invasively probe functionalised nanoparticle constructs at depths of many cm and to directly monitor the tissue surrounding them.  
2)    To focus on the development, testing and spectral monitoring of hyperthermia methods using light and magnetic field mediated nanoparticle heating of cells and tissues.  
3)    To focus on the development of Coherent Raman Scattering (CRS) microscopy to provide intracellular localisation of multiple NP cluster labels (multiplexed imaging) to demonstrate effective cellular uptake by target cells. 

The team will work together, also with those at the partner institutions, to develop novel healthcare technologies of the future. It is also an expectation that you will help to supervise PhD students working in an associated area of research to their own. 

About you

You will:

  • Possess a relevant PhD in Physics, Chemistry or Bioengineering or equivalent qualification/experience in a related field of study. 
  • Be a nationally recognised authority in one of the above subject areas and possess sufficient specialist knowledge in the discipline to develop advanced research programmes and methodologies. 
  • Be able to work collaboratively, supervise the work of others and act as team leader as required.
  • Have knowledge, skills and experience to be able to contribute significantly in at least one of the above roles.

For further information please contact Prof Nick Stone (RaNT Programme Director), e-mail n.stone@ex.ac.uk or telephone (01392) 726531; Prof Julian Moger (RaNT Co-Investigator), e-mail j.moger@ex.ac.uk; Dr Francesca Palombo (RaNT Co-Investigator), e-mail f.palombo@ex.ac.uk

The University of Exeter is an equal opportunity employer.  We are officially recognised as a Disability Confident employer and an Athena Swan accredited institution.  Whilst all applicants will be judged on merit alone, we particularly welcome applications from groups currently underrepresented in the workforce.  

The closing date for completed applications is Sunday 18 March 2018.