PhD Scholarship in Inflammation in Chronic Disease

Location
Brisbane, Australia
Posted
05 Jan 2018
End of advertisement period
11 Feb 2018
Ref
501738
Contract Type
Fixed Term
Hours
Full Time

PhD Scholarship in Inflammation in Chronic Disease

The position is available to undertake research in Inflammation in chronic disease at the Institute for Molecular Bioscience (http://www.imb.uq.edu.au). This research will entail multiple approaches including proteomics, structural biology, protein biochemistry and cell imaging. Applicants ideally will have completed courses or training in immunology, cell biology and/or biochemistry.

The University of Queensland's Institute for Molecular Bioscience is a leading global research institute. IMB was established in 2000 as UQ's first research institute and is the cornerstone of one of the largest bioscience research precincts in Australia. The Institute's 500 scientists, support staff and postgraduate students from more than 40 countries are working to improve quality of life for all. IMB has three major divisions and four research centres. IMB's multidisciplinary research programs focus on advancing medical genomics, drug discovery and biotechnology. By investigating the basis of growth and development at the genetic, molecular, cellular and organ level, our researchers aim to better understand the development processes and pathways involved in human and animal health and disease. They also work to translate these findings into diagnostics, technologies and therapeutics to more effectively prevent, detect and treat disease.

IMB is equipped with state-of-the-art research infrastructure including mouse and zebrafish facilities, advanced imaging and genomics platforms, high-throughput sequencing, advanced bioinformatics and proteomics – all of which support the Institute's leading life sciences research. Details of the research interests of the Institute may be accessed on the Institute's website at: http://www.imb.uq.edu.au

The role

We are seeking a dynamic, intelligent, highly motivated PhD student to work on the project that will be further developed with input from the successful applicant, but will focus on the following area:

Controlling inflammation in chronic disease.

Macrophages are regarded as ‘guardian immune cells’ functioning at the front line of innate immunity. By secreting an array of cytokines, macrophages also control inflammation throughout the body. However, in a wide variety of common diseases, including cancer, diabetes, Alzheimer’s and many others, inflammation is ‘out of control’. New ways to curtail macrophage function and inflammatory cytokines are urgently needed. As part of University of Queensland (UQ)/ Institute for Molecular Bioscience (IMB) ’s Centre for Inflammatory and Disease Research, we have identified a selective regulator of inflammatory responses, a protein called SCIMP.

In this project, the roles of SCIMP and its effectors, in Toll-like receptor-driven inflammation will be investigated. This research will entail multiple approaches including proteomics, structural biology, protein biochemistry and cell imaging. Applicants ideally will have completed courses or training in immunology, cell biology and/or biochemistry.

The project will be carried out in Professor Jenny Stow’s research group at IMB. (https://imb.uq.edu.au/protein-trafficking-and-inflammation)

For further information, please contact Dr Lin Luo (DECRA Fellow) by email l.luo@imb.uq.edu.au.

The Candidate

Both Australian and international applicants are welcome to apply. The successful candidate should have a First Class Honours Degree or Masters Degree (or equivalent), majoring in immunology, cell biology and/or biochemistry or a related discipline. Strong academic performance, good oral and written communication skills, and published output will be additional assessment criteria.

Applicants must be eligible to enrol in a PhD with the University of Queensland. For a complete list of the University of Queensland's minimum entry requirements please refer to: http://www.uq.edu.au/grad-school/our-research-degrees.

Scholarship and Remuneration

Selected prospective international and domestic students will receive assistance to apply for University living allowance and tuition fee scholarships.  The 2018 Research Training Program (RTP) living allowance stipend rate is AUD$27,082 (indexed annually), which is tax-free for three years with two possible extensions of up to 6 months each in approved circumstances (conditions apply).  For further information on scholarships refer to:  http://www.uq.edu.au/grad-school/scholarships-and-fees.

Award of the scholarship will be conditional upon the applicant applying for and obtaining an unconditional offer for entry to the PhD program at UQ, under the supervision of members of Prof Stow’s group and being assessed in the next available UQ scholarship round.

Enquiries and Application

For further information, please contact Dr Lin Luo (DECRA Fellow) by email l.luo@imb.uq.edu.au.

For application, please upload a cover letter and a full resume.

Application closing date is Sunday, 11 February 2018.

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