PhD Scholarship in Polymer Structures for Multiple Drug Delivery

Location
Boroondara, Australia
Posted
22 Dec 2017
End of advertisement period
31 Jan 2018
Ref
2178_12/17_A1
Contract Type
Fixed Term
Hours
Full Time
  • Mechanical Engineering and Product Design Engineering 
  • Polymer Structures for Multiple Drug Delivery 
  • 3 year PhD scholarship

About the scholarship 

Drug delivery systems and protocols to treat cancer come in many forms, and usually involve intrusive processes such as the application of catheters to allow chemotherapy, initial chemotherapy to shrink any cancer present, surgery to then remove the tumor(s) if possible, followed by more chemotherapy and radiation. In all cases, the effectiveness of the treatment is directly related to the treatment’s ability to target and to kill the cancer cells while affecting as few healthy cells as possible. The degree of change in the patient’s quality of life and eventual life expectancy is directly related to this targeting ability of the treatment. Localised treatment through in situ delivery of drugs where by a drug loaded depots are injected directly into the tumor is an attractive way to administer chemotherapy directly to the tumor. This approach avoids off-target effects as well as providing a larger localised dose delivery. However this approach is only suitable to cancers where access to the tumor is possible.

This PhD project will require the candidate to develop innovative advanced fabrication methods to form and characterise polymer microparticles that can be injected directly into target tumours for localised drug delivery. These polymeric monodispersed microparticles will contain a combination of anti-cancer agents (i.e., drug, peptides, cytokines etc) and plasmonic materials. These plasmonic materials will act as a MIR contrast agent as well as a means to initiate drug delivery using optical stimulation.

The main challenge of this project is the formation of the polymeric monodispersed microparticles that contain a combination of anti-cancer agents and plasmonic materials in the appropriate ratio to be effective.

Skills and experience

To be successful in this role you will need to demonstrate the following:   

  • 4 year honors degree (or equivalent) in science majoring in either;
    • Chemical Sciences
    • Biomedical Sciences 
  • Laboratory based research
  • Experience in biomaterials, 3D printing and stem cell or related areas

A full list of the selection criteria is available within the position description

How to apply

To start an application click on 'begin' at the bottom of this page and submit a resume, cover letter and response to the Key Selection Criteria, as listed in the Position Description below. Please do not email or send paper applications, all applications must be submitted online.

For further information about the position, please contact Yos Morsi (Professor of Biomechanical and Tissue Engineering) on +613 9214 8646.

If you are experiencing technical difficulties with your application, please contact the Recruitment team on +61 3 9214 8600 (option 2).

Applications close at 5pm on Wednesday 31st January 2018

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