Postdoctoral Fellow in HIV/SIV Research
Description of Work Unit
The Microbiology, Immunology and Pathology (MIP) Department is comprised of over 400 individuals who share a common passion for solving some of the most important human and animal health problems today. Research programs include those related to mycobacteria, retroviruses, prions, and arthropod-borne infectious diseases, as well as the diagnostic investigation of naturally-occurring animal diseases. A leader in education, MIP provides the only microbiology undergraduate degree program in Colorado, a graduate program that provides training in a number of cutting-edge disciplines, and several specialized veterinary residency training programs.
We are a molecular pathology/immunology laboratory that utilizes humanized mouse models (BLT, Rag-hu) to study Human immunodeficiency/Similan immunodeficiency virus (HIV/SIV) as well as Zika pathogenesis. Currently funded NIH (R01) projects include using humanized mice to investigate HIV-1 latency, antiretroviral therapy for pre/post-exposure prophylaxis, and evaluation of genomic changes involved in the evolution of SIV to HIV. Additional projects include CRISPR/Cas and modeling of Zika pathogenesis. The candidate will participate in several aspects of viral (HIV-1, HIV-2, SIV, Zika) pathogenesis and immunological research using humanized (BLT, Rag-hu) mice and in vitro models. See representative work: Neff CP et al Science Translational Medicine 3:66ra6, 2011, Veselinovic M et al Virology 489:173, 2016, Akkina R et al AIDSRes Hum Retroviruses 32:109, 2016, Bennett M et al Viruses 12:3119, 2013.
The Post-doctoral positions may become available throughout the year to study viral pathogenesis (retrovirus, flavivirus) in humanized mice. The opening is for a creative and self-motivated postdoctoral fellow in a biosafety level (BSL) 2 setting.
Colorado State University is located one hour north of Denver, CO in the heart of Fort Collins, CO. CSU provides resources to its faculty and staff that enable them to conduct cutting edge collaborative research and provides for outstanding intellectual environments and state-of-the-art facilities. Research discoveries conducted at CSU have led to the development of novel antiviral therapies and pertinent models for the study of viral pathogenesis in the context of translational medicine. Our scientific collaborations—and thus, their impact—extend from Fort Collins throughout the United States and Australia.
Required Job Qualifications
Applicants must have an earned PhD in immunology, molecular virology or a directly related field. Must show evidence of training in molecular biology techniques with flow cytometry and qRT-PCR experience. The successful candidate must demonstrate U.S. employment eligibility at time of application;CSU will not provide visa sponsorship for this position.
Preferred Job Qualifications
Prior experience in infectious disease research, immunology, and molecular biology and published work in peer-reviewed journals. Small animal handling experience desired. Candidate should also be able to demonstrate experience maintaining organized data, working collaboratively in a team oriented environment, conceptualizing and prioritizing objectives and exercising independent judgment.
Reflecting departmental and institutional values, candidates are expected to have the ability to advance the Department’s commitment to diversity and inclusion.
Job Duty Category Postdoctoral Researcher Duty/Responsibility
Research involving retroviruses/flaviviruses in vitro and in vivo in humanized mouse model. Conduct experiments in pathogenesis, gene therapy and pre/post exposure prophylaxis studies. See representative work: Berges BK et al, Virology 397:100-103, 2010, Neff CP et al Science Translational Medicine 3:66ra6, 2011, Veselinovic et al Virology 464-465:253-63, 2014 , Akkina R, Blood 122:2144, 2013
Percentage Of Time 90 Job Duty Category Grant and Manuscript writing Duty/Responsibility
Writing manuscripts on research results and assisting with grant reports.
Percentage Of Time 10
Special Instructions to Applicants
This pool is valid from October 5, 2016 to March 31, 2017, at which time the pool will renew and applicants wishing to remain in the pool must reapply.
Application must include a cover letter describing your education, experience, qualifications and skills specifically related to the position description; Curriculum Vitae; Unofficial Transcripts; and names and contact information of three professional references. References will not be contacted without prior notification of candidates
Conditions of Employment
Search Contact Ramesh Akkina, Ramesh.Akkina@colostate.edu
Colorado State University is committed to providing an environment that is free from discrimination and harassment based on race, age, creed, color, religion, national origin or ancestry, sex, gender, disability, veteran status, genetic information, sexual orientation, gender identity or expression, or pregnancy and will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. Colorado State University is an equal opportunity/equal access/affirmative action employer fully committed to achieving a diverse workforce and complies with all Federal and Colorado State laws, regulations, and executive orders regarding non-discrimination and affirmative action. The Office of Equal Opportunity is located in 101 Student Services.
Background Check Policy Statement
Colorado State University (CSU) strives to provide a safe study, work, and living environment for its faculty, staff, volunteers and students. To support this environment and comply with applicable laws and regulations, CSU conducts background checks. The type of background check conducted varies by position and can include, but is not limited to, criminal (felony and misdemeanor) history, sex offender registry, motor vehicle history, financial history, and/or education verification. Background checks will be conducted when required by law or contract and when, in the discretion of the university, it is reasonable and prudent to do so.