About Us

The role is situated in the Department of Twin Research and Genetic Epidemiology at King's College London, part of the School of Life Course and Population Sciences within the Faculty of Life Sciences and Medicine. The department focuses on cohorts including TwinsUK to better understand the genetic and environmental factors influencing health and disease. Its extensive research portfolio covers genetics, epigenetics, and environmental impacts—such as lifestyle and diet—on complex conditions like chronic pain, cardiovascular diseases, diabetes, and osteoporosis. The department also delves into ageing and the microbiome role in health, contributing significantly to genetic epidemiology and public health. Strong collaborations within KCL and with national and international partners further amplify the department's research impact and reach. 

About the role

This post will work on the genetic epidemiology of back pain, intervertebral disc degeneration and hearing loss, supporting the research activities of Prof Frances Williams (PI, Dept of Twin Research, School of Life Course Sciences). We are increasingly moving to multi-omic analysis of microbiome and metabolites to understand their relationship with chronic complex traits. The use of two sample Mendelian randomisation is allowing us to truly define the risk factors which cause common complex conditions, and how they interact with host genetics.

There will have a unique opportunity to work on data from important cohorts including TwinsUK and UK Biobank.  The applicant should be familiar with all aspects of genetic epidemiology including heritability studies, GWAS and multi-omic modelling.

There will also be opportunities to engage in other projects using deeply phenotyped cohorts, as well as with other projects involving genomics research and age-related diseases, in particular chronic pain and age-related hearing loss.

Applicants are expected to be able to direct research independently, supervise students and have a good breadth of knowledge of genetic epidemiology and epidemiology research methods and background. This post is within a highly supportive environment for both early- and mid-career researchers and the ability to work as part of a team is essential.

This is a full time post (35 hours per week), and you will be offered a fixed term contract until 30/09/2026.

About You

To be successful in this role, we are looking for candidates to have the following skills and experience:

Essential criteria

1. PhD awarded in genetic epidemiology or microbiome/metagenome, or genetics *
2. Sound knowledge of genomic epidemiology or statistical genetics
3. Ability to write manuscripts for publication
4. Knowledge of bioinformatics analysis methods, including ability to analyse microbiome data
5. Organised and systematic approach to research
6. Problem solving skills – both within the project and more broadly in the institution
7. Evidence of successful team-working
8. The ability to work under pressure & to meet deadlines

* Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6.

Desirable criteria

1. Experience with working across omics
2. Extensive experience in conferences, oral presentations and posters
3. Good publication record

Downloading a copy of our Job Description

Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the next page after you click “Apply Now”. This document will provide information of what criteria will be assessed at each stage of the recruitment process.

Further Information

We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community.

We are committed to working with our staff and unions on these and other issues, to continue to support our people and to develop a diverse and inclusive culture at King's.

We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.

To find out how our managers will review your application, please take a look at our ‘ How we Recruit’ pages.

Interviews are due to be held during May 2025.

We are able to offer sponsorship for candidates who do not currently possess the right to work in the UK.

Grade and Salary: £44,355 - £51,735 per annum, including London Weighting Allowance
Job ID: 113185
Close Date: 29-Apr-2025
Contact Person: Professor Frances Williams
Contact Details: frances.williams@kcl.ac.uk