About us

The Translational Immune Effector Cell Therapy Group at the Rayne Institute, Denmark Hill campus, translates novel chimeric antigen receptor T (CAR T) cells into the clinic for the treatment of patients with blood cancers.

About the role

We are seeking an experienced Research Assistant to join the Translational Immune Effector Cell Therapy Group at the Rayne Institute, Denmark Hill campus.  We are a new group which translates novel chimeric antigen receptor T (CAR T) cells into the clinic for the treatment of patients with blood cancers.

We perform pre-clinical work to aid submission to regulatory authorities. We develop molecular and flow cytometry assays to detect CAR T cells in patient samples for translational studies. Our laboratory is closely linked with the clinical haematology department at King’s College Hospital which has one of the largest CAR-T cell programmes in the UK. Diseases that we are currently targeting include multiple myeloma and B cell lymphoma, for which we have funding from Blood Cancer UK and Cancer Research UK.

Candidates applying for this role should have significant experience working within immunology and should be competent in flow cyometry including assay optimisation and panel design, previous experience using spectral flow cytometry would be ideal. Additionally, experience with PCR, and ideally digital droplet PCR is desirable.  Previous experience manufacturing research grade CAR T cells and performing functional assays is desirable.

The successful candidate will be expected to provide training in lab techniques to students within the group and help with the overall management of the lab.

This is a full time post (35 Hours per week), and you will be offered a fixed term contract until 27/04/2026.

About you

To be successful in this role, we are looking for candidates to have the following skills and experience:

Essential criteria 

1. Expertise in flow cytometry  
2. Expertise in molecular biology  
3. Ability to work independently 
4. Ability to supervise laboratory students 
5. Experience in laboratory management 
6. Data analysis

Desirable criteria

1. Experience in CAR T cell research 
2. Publications 

Downloading a copy of our Job Description

Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the next page after you click “Apply Now”. This document will provide information of what criteria will be assessed at each stage of the recruitment process.

Further information

This post is subject to Occupational Health clearances.

We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community. We are committed to working with our staff and unions on these and other issues, to continue to support our people and to develop a diverse and inclusive culture at King's.

We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.

To find out how our managers will review your application, please take a look at our ‘ How we Recruit’ pages.

Grade and Salary: £38,482 to £43,249 per annum, including London Weighting Allowance
Job ID: 109209
Close Date: 16-Mar-2025
Contact Person: Dr Charlotte Graham
Contact Details: Charlotte.2.graham@kcl.ac.uk