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Postdoctoral Research Associate in Cardiovascular Biology

Employer
KINGS COLLEGE LONDON
Location
London (Central), London (Greater)
Salary
£44,105 - £50,163 per annum, including London Weighting Allowance
Closing date
27 Feb 2025
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Job Details

About us

The School of Cardiovascular and Metabolic Medicine & Sciences (SCMMS), is one of six schools in the Faculty of Life Sciences & Medicine (FoLSM) at King College London. The School drives translation of world-leading basic science into advances in clinical practice in cardiac, vascular and metabolic medicine.  The School also hosts activities of the MRC/BHF Centre of Excellence for Advanced Cardiac Therapeutics (REACT) and the BHF Centre of Research Excellence at King’s.

About the role

Applications are invited for one talented and enthusiastic postdoctoral scientist to join Dr Lingfang Zeng’s laboratory at the School of Cardiovascular and Metabolic Medicine & Sciences at King's College London. The postholders will be part of a vibrant multi-disciplinary research group operating across different research themes in cardiac biology, having the specific aim to develop small peptides for cardiovascular protection.

In particular, the post-holders will investigate the effect and underlying mechanisms of histone deacetylase 7-derived 7-amino acid peptide (7A) on endothelial cells and evaluate its protection against cardiac fibrosis in myocardial infarction. This work will be performed in primary human aortic endothelial cells (HAECs) and umbilical vein endothelial cells (HUVECs) and 7A-deficient (HD7-7sFLAG) and Tie2-LacZ mouse myocardial infarction models, all of which are currently available in the laboratory

Minimum qualifications are PhD and/or MD with expertise in molecular and cellular biology and prior experience in animal surgery (ideally cardiac surgery), also for different applications.  Candidates should be highly motivated individuals with excellent communication skills and have the ability to work independently. The post holders will have the opportunity to write and publish results of research studies in high impact score peer-reviewed journals and report research results at international conferences.

The post is based within the School of Cardiovascular and Metabolic Medicine & Sciences at the James Black Centre (King’s Denmark Hill campus) as part of the King’s College London BHF Centre of Research Excellence and the MRC/BHF Centre for Advanced Cardiac Therapeutics (REACT). The School and these Centres provide an outstanding highly multidisciplinary environment with state-of-the-art equipment, facilities and technical support for both laboratory work and animal studies.

This is a full-time post (35 hours per week), and you will be offered a fixed term contract until 31st March 2028.

About you

To be successful in this role, we are looking for candidates to have the following skills and experience:

Essential criteria 

  1. PhD in relevant biological sciences and/or MD 
  2. Strong expertise in cellular and molecular biology 
  3. Knowledge in cardiovascular medicine  
  4. Self-motivated, ability to work independently 
  5. Commitment to continuing personal and professional development 
  6. Willing and able to work in a team 
  7. Flexible/able to respond to change in a current professional context

* Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6.

Desirable criteria

  1. Experience in animal models of cardiovascular disease 
  2. Experience in tissue and organ handling and processing, including histological analysis 
  3. Past experience in animal surgery  

Downloading a copy of our Job Description 

Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the next page after you click “Apply Now”. This document will provide information of what criteria will be assessed at each stage of the recruitment process.

Further information

This post is subject to Occupational Health clearances.

We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community. We are committed to working with our staff and unions on these and other issues, to continue to support our people and to develop a diverse and inclusive culture at King's.

We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.

To find out how our managers will review your application, please take a look at our ‘ How we Recruit’ pages.

We are able to offer sponsorship for candidates who do not currently possess the right to work in the UK.

Company

King's College London is one of the top 20 universities in the world and among the oldest in England. King's has more than 27,600 students (of whom nearly 10,500 are graduate students) from some 150 countries worldwide, and some 6,800 staff.

King's has an outstanding reputation for world-class teaching and cutting-edge research. In the 2014 Research Excellence Framework (REF) King’s was ranked 6th nationally in the ‘power’ ranking, which takes into account both the quality and quantity of research activity, and 7th for quality according to Times Higher Education rankings. Eighty-four per cent of research at King’s was deemed ‘world-leading’ or ‘internationally excellent’ (3* and 4*). The university is in the top seven UK universities for research earnings and has an overall annual income of more than £684 million.

King's has a particularly distinguished reputation in the humanities, law, the sciences (including a wide range of health areas such as psychiatry, medicine, nursing and dentistry) and social sciences including international affairs. It has played a major role in many of the advances that have shaped modern life, such as the discovery of the structure of DNA and research that led to the development of radio, television, mobile phones and radar.

King's College London and Guy's and St Thomas', King's College Hospital and South London and Maudsley NHS Foundation Trusts are part of King's Health Partners. King's Health Partners Academic Health Sciences Centre (AHSC) is a pioneering global collaboration between one of the world's leading research-led universities and three of London's most successful NHS Foundation Trusts, including leading teaching hospitals and comprehensive mental health services. For more information, visit: www.kingshealthpartners.org.

King’s £600 million campaign, World questions|KING’s answers, has delivered huge global impact in areas where King’s has particular expertise. Philanthropic support has funded new research to save young lives at Evelina London Children’s Hospital; established the King’s Dickson Poon School of Law as a worldwide leader in transnational law; built a new Cancer Centre at Guy’s Hospital; allowed unique collaboration between leading neuroscientists to fast-track new treatments for Alzheimer’s, Parkinson’s, motor neurone disease, depression and schizophrenia at the new Maurice Wohl Clinical Neuroscience Institute; created the Cicely Saunders Institute: the first academic institution in the world dedicated to palliative care, and supported the King’s Sierra Leone Partnership in the Ebola crisis. Donations provide over 300 of the most promising students with scholarships and bursaries each year. More information about the campaign is available at www.kcl.ac.uk/kingsanswers.

Company info
Mini-site
KINGS COLLEGE LONDON
Telephone
+(44)02078365454
Location
STRAND
LONDON
WC2R 2LS
GB

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