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Post-Doctoral Research Associate in Cardiovascular Virtual Twins

Employer
KINGS COLLEGE LONDON
Location
London (Central), London (Greater)
Salary
£44,105 - £47,632 per annum, including London Weighting
Closing date
16 Feb 2025
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Job Details

About us

A post-doctoral research associate position is available at King’s College London (KCL), funded by the European Commission Horizon 2023 project Virtual Twins as tools for Personalised Clinical Care (VITAL) ( https://vital-horizoneurope.eu). KCL, a world-leading research university over 200 years of heritage, is participating in VITAL by engaging the School of Biomedical Engineering & Imaging Sciences, a cutting-edge research and teaching institution located in St Thomas’ Hospital. The school is dedicated to the development, clinical translation, and clinical application of medical imaging and computational modelling technologies.

KCL's contribution to VITAL will primarily focus on the computational modelling work packages of the project, leveraging our expertise in reduced-order blood flow modelling ( http://haemod.uk/nektar) and haemodynamic signal analysis ( http://haemod.uk/PWA ), and the creation and testing of large-scale in silico pulse wave datasets ( http://haemod.uk/virtual-database).

About the role

The post holder will contribute to the development and clinical validation of the VITAL digital twins for personalised cardiovascular care. These advanced models aim to predict disease progression and optimise patient management strategies, surpassing current clinical standards. VITAL’s virtual twins will be used to study four complex circulation overload disorders – systemic hypertension, heart failure, and hemodynamically complicated atrial septal defects – examining the interplay between cardiac and vascular function, renal and hormonal influences, and various environmental and genetic factors. The technology, developed with input from healthcare professionals, will be validated in over 200 patients across five clinical studies in France and the UK.

The post-holder will develop a multi-scale, multi-organ model of arterial and venous blood flow, integrating existing and newly developed 0D, 1D, and 3D codes into a computationally efficient, modular framework. The role involves close collaboration with modelling experts from the Universities of Auckland, Delft, EPFL, and other industrial and clinical partners. The codes developed by VITAL will be linked to EDITH, an ecosystem for digital twins in healthcare. The post-holder will work under the supervision of Professor Philip Chowienczyk (clinical advisor), and Drs Peter Charlton and Jordi Alastruey (modelling advisors), with the expectation to publish in high-impact journals and present findings at international conferences.

This is a full-time post (100% full time equivalent), and you will be offered a fixed term contract for 2 and a half years.

About you

To be successful in this role, we are looking for candidates to have the following skills and experience:

Essential criteria 

  1. PhD awarded, or near completion*, in biomedical engineering, physics, mathematics, or a related subject.
  2. First or second class honors degree in biomedical engineering, physics, mathematics, or a related subject.
  3. Advanced programming skills in Python, Matlab and C++.
  4. Good writing and presentation skills. 
  5. A solid research background in a relevant field, supported by published peer-reviewed work. 
  6. Ability to work independently and as part of a team. 
  7. Ability to work and communicate effectively with people from a wide range of disciplines and organisations. 
  8. An enthusiastic attitude and scientific approach to solving research problems.

Desirable criteria

  1. Knowledge of cardiovascular physiology
  2. Knowledge of signal and image processing techniques 
  3. Experience with student supervision  
  4. Experience in multidisciplinary research
  5. Evidence of leading own initiatives/projects 

Downloading a copy of our Job Description

Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the next page after you click “Apply Now”. This document will provide information of what criteria will be assessed at each stage of the recruitment process.

Further information

We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community. We are committed to working with our staff and unions on these and other issues, to continue to support our people and to develop a diverse and inclusive culture at King's.

We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.

To find out how our managers will review your application, please take a look at our ‘ How we Recruit’ pages.

We are able to offer sponsorship for candidates who do not currently possess the right to work in the UK.

Company

King's College London is one of the top 20 universities in the world and among the oldest in England. King's has more than 27,600 students (of whom nearly 10,500 are graduate students) from some 150 countries worldwide, and some 6,800 staff.

King's has an outstanding reputation for world-class teaching and cutting-edge research. In the 2014 Research Excellence Framework (REF) King’s was ranked 6th nationally in the ‘power’ ranking, which takes into account both the quality and quantity of research activity, and 7th for quality according to Times Higher Education rankings. Eighty-four per cent of research at King’s was deemed ‘world-leading’ or ‘internationally excellent’ (3* and 4*). The university is in the top seven UK universities for research earnings and has an overall annual income of more than £684 million.

King's has a particularly distinguished reputation in the humanities, law, the sciences (including a wide range of health areas such as psychiatry, medicine, nursing and dentistry) and social sciences including international affairs. It has played a major role in many of the advances that have shaped modern life, such as the discovery of the structure of DNA and research that led to the development of radio, television, mobile phones and radar.

King's College London and Guy's and St Thomas', King's College Hospital and South London and Maudsley NHS Foundation Trusts are part of King's Health Partners. King's Health Partners Academic Health Sciences Centre (AHSC) is a pioneering global collaboration between one of the world's leading research-led universities and three of London's most successful NHS Foundation Trusts, including leading teaching hospitals and comprehensive mental health services. For more information, visit: www.kingshealthpartners.org.

King’s £600 million campaign, World questions|KING’s answers, has delivered huge global impact in areas where King’s has particular expertise. Philanthropic support has funded new research to save young lives at Evelina London Children’s Hospital; established the King’s Dickson Poon School of Law as a worldwide leader in transnational law; built a new Cancer Centre at Guy’s Hospital; allowed unique collaboration between leading neuroscientists to fast-track new treatments for Alzheimer’s, Parkinson’s, motor neurone disease, depression and schizophrenia at the new Maurice Wohl Clinical Neuroscience Institute; created the Cicely Saunders Institute: the first academic institution in the world dedicated to palliative care, and supported the King’s Sierra Leone Partnership in the Ebola crisis. Donations provide over 300 of the most promising students with scholarships and bursaries each year. More information about the campaign is available at www.kcl.ac.uk/kingsanswers.

Company info
Mini-site
KINGS COLLEGE LONDON
Telephone
+(44)02078365454
Location
STRAND
LONDON
WC2R 2LS
GB

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