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Product Development Scientist - Organoids and Microphysiological Systems (MPS)

Employer
Advanced Biomedical Instrumentation Centre Ltd
Location
Hong Kong
Closing date
16 Feb 2025
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Advanced Biomedical Instrumentation Centre Limited (ABIC) is a collaborative effort coordinated by the University of Hong Kong (HKU) undertaking R&D projects at the Hong Kong Science Park. The aim of ABIC is to develop new and disruptive technologies that will meet the needs of the healthcare sector and contribute to human health. Applications are invited for appointments as Product Development Scientist (Ref.: H01/2025/016) for innovative technology and product development projects specifically in the field of Organoids and Microphysiological Systems (MPS).

Job Description

  • Designing, developing, and optimizing novel organoid culture protocols, with a strong focus on patient-derived organoids and cancer organoids.
  • Establishing robust 3D cell culture models, including optimization of culture media, extracellular matrix components, and growth factors.
  • Integrating organoid models into Microphysiological Systems (MPS) to create physiologically relevant in vitro platforms.
  • Developing and optimizing assays for drug screening, toxicity testing, and mechanistic studies using organoid and MPS.
  • Conducting experiments to evaluate the efficacy and safety of novel therapeutic agents.
  • Staying abreast of the latest scientific literature and technological advancements in the fields of organoids, MPS, and cancer biology.
  • Translating research outcomes into marketable applications and business opportunities
  • Writing proposals, reports, articles, patents, technical specifications, and other publications
  • Delivering high-quality presentations to collaborators and partners
  • Handling other relevant tasks as assigned by the supervisor(s)

Requirements

  • PhD in Cell Biology, Biotechnology, Bioengineering, or related life sciences disciplines
  • Mature, self-motivated, and able to work under pressure
  • Highly proficient and fluent in English in both writing and verbal communications
  • 1+ years of relevant industry (corporate, non-academic) R&D experience in the biotech sector is a MUST, with the following capabilities:
    • Demonstrated expertise in 3D cell culture techniques, with a strong emphasis on organoid culture.
    • Hands-on experience with patient-derived organoid (PDO) culture and characterization
    • Experience with microphysiological systems (MPS) design, fabrication, and operation is highly desirable
    • Understanding of cancer medicine, including mechanisms of tumorigenesis, oncological drug delivery, and drug resistance
    • Experienced in a wide range of cell biology and drug screening techniques, such as immunofluorescence, microscopy, PCR, flow cytometry, toxicology assays, etc.
    • More experienced candidate can be hired for the Staff Scientist position.
    • Experience with Contract Research Organization (CRO) or Laboratory Developed Test (LDT) services is a definite advantage

A highly competitive salary commensurate with qualifications and experience will be offered, in addition to annual leave and medical benefits.

Applicants should submit their up-to-date C.V., quoting the job reference number, with information on current/expected remuneration and availability, to hr@abic.hk. Review of applications will commence as soon as possible and until the posts are filled.

The personal data provided in your application process will be used for recruitment and other employment-related purpose. The personal data may be transferred and disclosed to, and used by HKU Innovation Holdings Limited and The University of Hong Kong for the above purposes.

We are an equal opportunities employer and welcome applications from all qualified candidates.

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