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Senior Technician/Senior Technical Officer

Employer
KINGS COLLEGE LONDON
Location
London (Central), London (Greater)
Salary
£37,332 - £45,521 per annum depending on experience, including London Weighting Allowance
Closing date
26 May 2024

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Job Details

About us

The School of Cardiovascular and Metabolic Medicine & Sciences (SCMMS) provides an outstanding multi-disciplinary environment for the pursuit of cutting-edge cardiovascular and metabolic research. We study the fundamental molecular, cellular, and physiological processes that underly normal and abnormal cardiovascular and metabolic function and drive the translation of this strong basic science into advances in clinical practice. Our research focuses on four main Themes (Cardiac, Vascular, Cardiometabolic, Diabetes & Obesity), with two cross-cutting Themes (Basic and Clinical). The School is led by Professor Mauro Giacca and comprises over 65 clinical and non-clinical academic groups, hosting 400 personnel and 110 PhD students. Our community of world-renowned researchers and educators have access to state-of-the art core facilities and expertise, including facilities for high-throughput screening and high content imaging, multimodality in vivo imaging, proteomics, integrative physiology and viral & non-viral vector production. The School activities are carried out at three main locations: James Black Centre in Denmark Hill, St Thomas’s Hospital and Franklin-Wilkins Building in South Bank and the Hodgkin Building and New Hunt House/Randal Centre in Guy’s Campus. As part of King’s Health Partners, we have an excellent environment for basic-clinical interaction and a strong focus on mentoring and career development. The School hosts the British Heart Foundation Centre of Research Excellence at King's, which brings together a unique range of internationally recognised scientists and clinicians from across the School and King’s College London.

More information: https://www.kcl.ac.uk/scmms

About the role

Applications are invited for a talented and enthusiastic Senior Technician/Senior Technical Officer to join Prof Mauro Giacca’s and Dr Miguel Mano’s laboratories at the School of Cardiovascular and Metabolic Medicine & Sciences at King's College London. The postholder will be part of a vibrant multi-disciplinary environment across different research themes in cardiac biology. 

The post holder will provide high quality technical support to the groups and their associated research activities. In particular, the post holder will work within the scope of activities of the High-Throughput/High-Content Screening Facility (HCS) under the supervision of the Head of the facility, Dr. Mano.

It is expected that 80% of the time will be spent on ensuring smooth operation of the HCS Facility, supporting, on a daily basis, cell biology procedures (i.e. cell culture and transfection), high-content microscopy-assay development (i.e. immunofluorescence assays, live cell assays, gene reporter assays), image acquisition using dedicated equipment and specialist software, provision of basic training on image acquisition and analysis, handling of genomic and small molecule libraries, and maintenance of adequate supplies for the above-mentioned activities.

The rest of the time will be spent providing experimental support to the two Groups and participating in School’s projects and activities as directed.

This role can be offered at a Senior Technician (Grade 5) or Senior Technical Officer (Grade 6) depending on the level of experience.

This is a full time post (35 Hours per week), and you will be offered a fixed term contract until 30 September 2025 with the possibility of further extension.

About You

To be successful in this role, we are looking for candidates to have the following skills and experience:

Senior Technician (Grade 5) 

Essential criteria

  1. Relevant degree or significant professional experience in high throughput screening (academia/industry).
  2. Comprehensive technical knowledge and skills in a broad range of experimental methods and scientific practices.
  3. Previous experience in molecular and cellular biology (cell culture, transfection, immunofluorescence), histology, and advanced microscopy.
  4. Excellent spoken and written communication skills, and strong interpersonal skills
  5. Well-developed analytical capabilities, gathering, manipulating, interpreting, evaluation and analysing data, information, concepts, and ideas.
  6. Planning and organization skills, with the ability to work independently with minimal supervision and to manage competing priorities and changing.

Desirable criteria

  1. Able and willing to provide support beyond core hours, as required.
  2. Previous experience working with high-content microscopy and automated image analysis, liquid handling platforms, and cell culture systems.
  3. Previous experience experimental approaches for gene modulation (e.g. siRNA, microRNA, CRISPR) and/or in development of assays for large-scale high-throughput/high-content screenings.
  4. Computational/programming skills for implementation of image/data analysis and data visualization workflows (e.g. R, Python). 
  5. Knowledge and understanding of the Laboratory Health and Safety Regulations (COSSH) governing the area of work, with NEBOSH/IOSH certification in relevant areas such as cryogenic gases safety training.

Senior Technical Officer (Grade 6)  

Essential criteria

  1. Relevant PhD degree or significant professional experience in high throughput screening (academia/industry).
  2. Comprehensive technical knowledge and skills in a broad range of experimental methods and scientific practices.
  3. Previous experience in molecular and cellular biology (cell culture, transfection, immunofluorescence), histology, and advanced microscopy.
  4. Excellent spoken and written communication skills, and strong interpersonal skills
  5. Well-developed analytical capabilities, gathering, manipulating, interpreting, evaluation and analysing data, information, concepts, and ideas.
  6. Planning and organization skills, with the ability to work independently with minimal supervision and to manage competing priorities and changing.
  7. Knowledge and understanding of the Laboratory Health and Safety Regulations (COSSH) governing the area of work, with NEBOSH/IOSH certification in relevant areas such as cryogenic gases safety training.
  8. Prior experience in laboratory automatization or use/management of complex laboratory instrumentation

Desirable criteria

  1. Able and willing to provide support beyond core hours, as required.
  2. Previous experience working with high-content microscopy and automated image analysis, liquid handling platforms, and cell culture systems.
  3. Previous experience experimental approaches for gene modulation (e.g. siRNA, microRNA, CRISPR) and/or in development of assays for large-scale high-throughput/high-content screenings.
  4. Computational/programming skills for implementation of image/data analysis and data visualization workflows (e.g. R, Python).

This role can be offered at a Senior Technician (Grade 5) or Senior Technical Officer (Grade 6) depending on level of experience.

Further information

This post is subject to Occupational Health clearances.

We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community.

We are committed to working with our staff and unions on these and other issues, to continue to support our people and to develop a diverse and inclusive culture at King's. We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.

To find out how our managers review your application, please take a look at our ‘How we Recruit’ pages.

Company

King's College London is one of the top 20 universities in the world and among the oldest in England. King's has more than 27,600 students (of whom nearly 10,500 are graduate students) from some 150 countries worldwide, and some 6,800 staff.

King's has an outstanding reputation for world-class teaching and cutting-edge research. In the 2014 Research Excellence Framework (REF) King’s was ranked 6th nationally in the ‘power’ ranking, which takes into account both the quality and quantity of research activity, and 7th for quality according to Times Higher Education rankings. Eighty-four per cent of research at King’s was deemed ‘world-leading’ or ‘internationally excellent’ (3* and 4*). The university is in the top seven UK universities for research earnings and has an overall annual income of more than £684 million.

King's has a particularly distinguished reputation in the humanities, law, the sciences (including a wide range of health areas such as psychiatry, medicine, nursing and dentistry) and social sciences including international affairs. It has played a major role in many of the advances that have shaped modern life, such as the discovery of the structure of DNA and research that led to the development of radio, television, mobile phones and radar.

King's College London and Guy's and St Thomas', King's College Hospital and South London and Maudsley NHS Foundation Trusts are part of King's Health Partners. King's Health Partners Academic Health Sciences Centre (AHSC) is a pioneering global collaboration between one of the world's leading research-led universities and three of London's most successful NHS Foundation Trusts, including leading teaching hospitals and comprehensive mental health services. For more information, visit: www.kingshealthpartners.org.

King’s £600 million campaign, World questions|KING’s answers, has delivered huge global impact in areas where King’s has particular expertise. Philanthropic support has funded new research to save young lives at Evelina London Children’s Hospital; established the King’s Dickson Poon School of Law as a worldwide leader in transnational law; built a new Cancer Centre at Guy’s Hospital; allowed unique collaboration between leading neuroscientists to fast-track new treatments for Alzheimer’s, Parkinson’s, motor neurone disease, depression and schizophrenia at the new Maurice Wohl Clinical Neuroscience Institute; created the Cicely Saunders Institute: the first academic institution in the world dedicated to palliative care, and supported the King’s Sierra Leone Partnership in the Ebola crisis. Donations provide over 300 of the most promising students with scholarships and bursaries each year. More information about the campaign is available at www.kcl.ac.uk/kingsanswers.

Company info
Mini-site
KINGS COLLEGE LONDON
Telephone
+(44)02078365454
Location
STRAND
LONDON
WC2R 2LS
GB

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