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Postdoctoral Research Associate

Employer
KINGS COLLEGE LONDON
Location
London (Central), London (Greater)
Salary
£43,205 - £44,347 per annum, including London Weighting Allowance
Closing date
2 Jun 2024

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Job Details

About us

The School of Cardiovascular and Metabolic Medicine & Sciences (SCMMS), is one of six schools that make up the Faculty of Life Sciences & Medicine (FoLSM) at King College London. The School drives translation of world-leading basic science into advances in clinical practices with activities focusing on the Cardiac Biomedicine Department of Diabetes and Vascular Biomedicine.

About the role

This position is for a talented and enthusiastic postdoctoral scientist to work on a BHF Project Grant led by Dr. Anna Zoccarato and Prof. Ajay Shah on the role of changes in cardiac metabolism to pathological cardiac remodelling, with specific focus on glucose anabolic pathways and stress responses.

The project will involve the use of i) iPSC-derived cardiomyocytes and "engineered heart tissues (EHT)" and ii) experimental in vivo models of cardiac disease. We therefore seek to appoint an individual with a strong background in cell/molecular biology and experience of working with iPSC-derived cardiomyocytes or EHT. Previous experience with in vivo mouse models and in vivo phenotyping (e.g. high-resolution echocardiography) is desirable. The project will also offer experience in metabolomic assays, prior experience in this area is desirable but not essential. The postholder will be part of a vibrant multi-disciplinary research group working on several different aspects of cardiovascular pathophysiology, within the King’s BHF Centre of Research Excellence which has state-of-the-art laboratory facilities.

This is a full-time post (35 Hours per week), and you will be offered a fix-term contract for 3 years.

About You

To be successful in this role, we are looking for candidates to have the following skills and experience:

Essential criteria

  1. PhD in a relevant biological sciences project.
  2. Strong background in cell and molecular biology e.g. primary cell culture, confocal microscopy, immunofluorescence, western blotting, qPCR)
  3. Successful completion of research projects (published papers in high Impact Factor journals). 
  4. Good written presentation skills, communication skills (written & verbal), and good IT skills 
  5. Commitment to continuing personal and professional development. 
  6. Self-motivated, able to work independently, as well as willing and able to work as part of a team. 
  7. Able to carry out known/learnt techniques unsupervised, and flexible/able to change in current professional context. 
  8. Able to plan and prioritise workload and keep clear and well-organised laboratory notes and records.

Desirable criteria

  1. Background in cardiovascular biology.
  2. Experience of working with iPS-derived cardiomyocytes or engineered heart tissues.
  3. Experience in gene-modified models and in vivo cardiovascular physiology (e.g. echo).
  4. Home Office Personal Licence or equivalent.
  5. Knowledge of mass spectrometry data analysis, data interpretation and computational methods using software such as Metaboanalyst, MassHunter Profinder. 

Full details of the role and the skills and experience required, can be found in the attached job description which provided on the next page.

* Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6.

Further information

This post is subject to Occupational Health clearances.

We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community.

We are committed to working with our staff and unions on these and other issues, to continue to support our people and to develop a diverse and inclusive culture at King's. We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.

To find out how our managers review your application, please take a look at our ‘How we Recruit’ pages.

Interviews are due to be held week commencing 17th June 24.

Company

King's College London is one of the top 20 universities in the world and among the oldest in England. King's has more than 27,600 students (of whom nearly 10,500 are graduate students) from some 150 countries worldwide, and some 6,800 staff.

King's has an outstanding reputation for world-class teaching and cutting-edge research. In the 2014 Research Excellence Framework (REF) King’s was ranked 6th nationally in the ‘power’ ranking, which takes into account both the quality and quantity of research activity, and 7th for quality according to Times Higher Education rankings. Eighty-four per cent of research at King’s was deemed ‘world-leading’ or ‘internationally excellent’ (3* and 4*). The university is in the top seven UK universities for research earnings and has an overall annual income of more than £684 million.

King's has a particularly distinguished reputation in the humanities, law, the sciences (including a wide range of health areas such as psychiatry, medicine, nursing and dentistry) and social sciences including international affairs. It has played a major role in many of the advances that have shaped modern life, such as the discovery of the structure of DNA and research that led to the development of radio, television, mobile phones and radar.

King's College London and Guy's and St Thomas', King's College Hospital and South London and Maudsley NHS Foundation Trusts are part of King's Health Partners. King's Health Partners Academic Health Sciences Centre (AHSC) is a pioneering global collaboration between one of the world's leading research-led universities and three of London's most successful NHS Foundation Trusts, including leading teaching hospitals and comprehensive mental health services. For more information, visit: www.kingshealthpartners.org.

King’s £600 million campaign, World questions|KING’s answers, has delivered huge global impact in areas where King’s has particular expertise. Philanthropic support has funded new research to save young lives at Evelina London Children’s Hospital; established the King’s Dickson Poon School of Law as a worldwide leader in transnational law; built a new Cancer Centre at Guy’s Hospital; allowed unique collaboration between leading neuroscientists to fast-track new treatments for Alzheimer’s, Parkinson’s, motor neurone disease, depression and schizophrenia at the new Maurice Wohl Clinical Neuroscience Institute; created the Cicely Saunders Institute: the first academic institution in the world dedicated to palliative care, and supported the King’s Sierra Leone Partnership in the Ebola crisis. Donations provide over 300 of the most promising students with scholarships and bursaries each year. More information about the campaign is available at www.kcl.ac.uk/kingsanswers.

Company info
Mini-site
KINGS COLLEGE LONDON
Telephone
+(44)02078365454
Location
STRAND
LONDON
WC2R 2LS
GB

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