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Research Associate in Vascular Biology

Employer
KINGS COLLEGE LONDON
Location
London (Central), London (Greater)
Salary
£43,205 - £45,521per annum, including London Weighting Allowance
Closing date
12 May 2024

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Job Details

About us

The School of Cardiovascular and Metabolic Medicine & Sciences (SCMMS) provides an outstanding multi-disciplinary environment for the pursuit of cutting-edge cardiovascular and metabolic research. We study the fundamental molecular, cellular, and physiological processes that underly normal and abnormal cardiovascular and metabolic function and drive the translation of this strong basic science into advances in clinical practice.

Our research focuses on four main Themes (Cardiac, Vascular, Cardiometabolic, Diabetes & Obesity), with two cross-cutting Themes (Basic and Clinical). The School is led by Professor Mauro Giacca and comprises over 65 clinical and non-clinical academic groups, hosting 400 personnel and 110 PhD students. Our community of world-renowned researchers and educators have access to state-of-the art core facilities and expertise, including facilities for high-throughput screening and high content imaging, multimodality in vivo imaging, proteomics, integrative physiology, and viral & non-viral vector production.

The School activities are carried out at three main locations: James Black Centre in Denmark Hill, St Thomas’s Hospital and Franklin-Wilkins Building in South Bank and the Hodgkin Building and New Hunt House/Randal Centre in Guy’s Campus.

As part of King’s Health Partners, we have an excellent environment for basic-clinical interaction and a strong focus on mentoring and career development. The School hosts the British Heart Foundation Centre of Research Excellence at King's, which brings together a unique range of internationally recognised scientists and clinicians from across the School and King’s College London.

About the role

This is an exciting opportunity to join Professor Gnudi’s team in the Vascular Biology & Inflammation section of Southbank, School of Cardiovascular and Metabolic Medicine & Sciences at King’s College London.

To conduct a period of original research leading to publications and future grant application working with Prof Luigi Gnudi - School of Cardiovascular and Metabolic Medicine & Sciences.

Prof Gnudi is an internationally recognised clinical scientist who has described novel important role of vascular growth factors (angiopoietins) in the renal vasculature.

This project will look at kidney disease as an important vascular complication of diabetes and at a novel identified molecule that modulates the angiopoietin signalling by acting on Tie-2/Tie-1 receptor.

We will test whether Tie1 inducible deletion, specifically in endothelial cells influences healthy and diabetic kidneys and whether Tie-1 can be modulated as a target for treatment of the diabetic vasculature in the kidney.

This work will be conducted using state of the art technologies, in a vibrant environment of basic scientist, physiologist and clinicians, an ideal setting for translation of lab-based observations to the clinical setting.

This is a full-time post (35 Hours per week), and you will be offered a fix-term contract for 19 months.

About You

To be successful in this role, we are looking for candidates to have the following skills and experience:

Essential criteria

  1. BSc (at least 2:1) or equivalent 
  2. PhD or MD or equivalent
  3. Able to work independently
  4. Animal work experience and/or willingness to work with animals 
  5. Previous experience in biological /medical research 
  6. Good organisation, presentation, and IT skills
  7. Excellent communication, interpersonal skills, and team player
  8. Self-motivated

Desirable criteria

  1. Academic prizes
  2. Knowledge of vascular renal physiology
  3. Committed to own continuing professional development and willing to undertake any training required

Full details of the role and the skills and experience required, can be found in the attached job description which provided on the next page.

* Please note that this is a PhD/MD level role but candidates who have submitted their thesis and are awaiting award of their PhDs/MD will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6.

Further information

This post is subject to Occupational Health clearances.

We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community. 

We are committed to working with our staff and unions on these and other issues, to continue to support our people and to develop a diverse and inclusive culture at King's.

We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.

To find out how our managers review your application, please look at our ‘How we Recruit’ pages.

Interviews are due to be held in June 2024.

This role does meet the requirements of the Home Office and therefore we are able to offer sponsorship for candidates who require the right to work in the UK. 

Company

King's College London is one of the top 20 universities in the world and among the oldest in England. King's has more than 27,600 students (of whom nearly 10,500 are graduate students) from some 150 countries worldwide, and some 6,800 staff.

King's has an outstanding reputation for world-class teaching and cutting-edge research. In the 2014 Research Excellence Framework (REF) King’s was ranked 6th nationally in the ‘power’ ranking, which takes into account both the quality and quantity of research activity, and 7th for quality according to Times Higher Education rankings. Eighty-four per cent of research at King’s was deemed ‘world-leading’ or ‘internationally excellent’ (3* and 4*). The university is in the top seven UK universities for research earnings and has an overall annual income of more than £684 million.

King's has a particularly distinguished reputation in the humanities, law, the sciences (including a wide range of health areas such as psychiatry, medicine, nursing and dentistry) and social sciences including international affairs. It has played a major role in many of the advances that have shaped modern life, such as the discovery of the structure of DNA and research that led to the development of radio, television, mobile phones and radar.

King's College London and Guy's and St Thomas', King's College Hospital and South London and Maudsley NHS Foundation Trusts are part of King's Health Partners. King's Health Partners Academic Health Sciences Centre (AHSC) is a pioneering global collaboration between one of the world's leading research-led universities and three of London's most successful NHS Foundation Trusts, including leading teaching hospitals and comprehensive mental health services. For more information, visit: www.kingshealthpartners.org.

King’s £600 million campaign, World questions|KING’s answers, has delivered huge global impact in areas where King’s has particular expertise. Philanthropic support has funded new research to save young lives at Evelina London Children’s Hospital; established the King’s Dickson Poon School of Law as a worldwide leader in transnational law; built a new Cancer Centre at Guy’s Hospital; allowed unique collaboration between leading neuroscientists to fast-track new treatments for Alzheimer’s, Parkinson’s, motor neurone disease, depression and schizophrenia at the new Maurice Wohl Clinical Neuroscience Institute; created the Cicely Saunders Institute: the first academic institution in the world dedicated to palliative care, and supported the King’s Sierra Leone Partnership in the Ebola crisis. Donations provide over 300 of the most promising students with scholarships and bursaries each year. More information about the campaign is available at www.kcl.ac.uk/kingsanswers.

Company info
Mini-site
KINGS COLLEGE LONDON
Telephone
+(44)02078365454
Location
STRAND
LONDON
WC2R 2LS
GB

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