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Research Associate (Bioinformatician)

Employer
KINGS COLLEGE LONDON
Location
London (Greater) (GB)
Salary
£42,405 - £47,178 per annum, including London Weighting Allowance
Closing date
4 Jan 2024

Job Details

Job Description

This is an exciting opportunity to join an internationally leading interdisciplinary team of King’s College London, Oxford University and Surrey University scientists working on the ‘Mind & Skin’ research programme.

Funded by the UK Medical Research Foundation, we are generating complex sleep monitoring, brain imaging and skin phenotyping data to understand the mechanisms underpinning adolescent skin disorders. We will employ machine learning, artificial intelligence and data integration approaches to study potential links between atopic dermatitis (AD), pruritus, sleep disturbance and altered brain function, including cognitive changes.

The bioinformatician will work under the supervision of Dr. Alessandra Vigilante, Senior Lecturer in Bioinformatics, and Professor Carsten Flohr, Chair in Dermatology and Population Health Science and Mind & Skin Chief Investigator, and be embedded in the new KCL Hub for Applied Bioinformatics (HAB). S/he will provide support in the data integration analyses as well as statistical analysis of data. The main purpose of the role encompasses performing data integration and statistical analysis while offering comprehensive data-driven decision support by overseeing the cleaning, integration, and analysis of diverse datasets. This crucially involves collaborating closely with the interdisciplinary team to ensure the harmonization and cleanliness of multiple datasets, with the ultimate goal of uncovering connections between adolescent skin disorders, sleep disruptions, and altered brain function in the 'Mind & Skin' research programme.

We look for an ambitious candidate with established expertise in bioinformatics, specifically dealing with large data sets and data integration. Knowledge of python and R are essential.

Further information about the Mind & Skin project is found here:

 https://www.youtube.com/watch?v=S6MRTNxDoqo

https://onlinelibrary.wiley.com/doi/10.1111/all.15818

For more information about the post, please contact Alessandra Vigilante (alessandra.vigilante@kcl.ac.uk) and Carsten Flohr (carsten.flohr@kcl.ac.uk).

About the Faculty:

King’s College London Faculty of Life Sciences and Medicine is one of the largest and most successful centres for research and education in the University. It consists of over 2000 staff and 5000 students within seven Schools and two Schools of Education.

The FoLSM Applied Bioinformatics Hub, home of a new and interdisciplinary network, is located on the Guy’s Campus in central London. It acts as a nucleus for a vibrant research community spanning the entire Faculty, bringing together researchers involved in different research areas such as computational genomics, genetics, cancer genomics, dermatology, immunology, reproductive biology and child health, cardiovascular research, neurobiology, evolutionary biology, pharmacology and others.

Hub for Applied Bioinformatics (HAB)

 https://www.kcl.ac.uk/research/the-hub-for-applied-bioinformatics-hab

This is an interdisciplinary cross-cutting network that brings together academics, clinicians and staff with different expertise and requirements, to support and undertake ground-breaking research involving big data, and deliver high-level education programs. It acts as a nucleus for a vibrant research community, spanning the entire Faculty of Life Science and Medicine.

This post will be offered on a fixed-term contract until February 2027.

This is a full-time post - 100% full time equivalent.

Key responsibilities

  • Provide bioinformatics expertise to help the Mind & Skin programme members to achieve the research objectives. 
  • Data and statistical analysis
  • Dataset integration
  • Keep an excellent record of analysis 
  • Prepare and present data to colleagues and other scientists 
  • Contribute to the production of research reports and publications 
  • The post holder may be asked to contribute bioinformatics expertise to other projects led by Professor Carsten Flohr. 

The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.

Skills, knowledge, and experience

Essential criteria

  1. PhD degree
  2. Previous experience working in bioinformatics with large datasets
  3. Previous experience in statistical analysis of data
  4. Excellent scientific analysis skills
  5. Excellent computer skills and programming (Python and R)
  6. Previous experience with imaging data analysis
  7. A deep technical understanding of bioinformatics analysis approaches and data.
  8. Self-motivated, enthusiastic and problem-solving attitude
  9. Very good oral and written communication skills
  10. The ability to mentor and develop bioinformaticians at all stages of the analysis project workflow

Desirable criteria

  1. Experience integrating different datasets
  2. Excellent computational skills applied to HPC, big data, software development and web technologies.
  3. Bioinformatics community network connections.
  4. Experience in teaching bioinformatics.
  5. Previous experience with AI and/or machine learning approaches

Company

King's College London is one of the top 20 universities in the world and among the oldest in England. King's has more than 27,600 students (of whom nearly 10,500 are graduate students) from some 150 countries worldwide, and some 6,800 staff.

King's has an outstanding reputation for world-class teaching and cutting-edge research. In the 2014 Research Excellence Framework (REF) King’s was ranked 6th nationally in the ‘power’ ranking, which takes into account both the quality and quantity of research activity, and 7th for quality according to Times Higher Education rankings. Eighty-four per cent of research at King’s was deemed ‘world-leading’ or ‘internationally excellent’ (3* and 4*). The university is in the top seven UK universities for research earnings and has an overall annual income of more than £684 million.

King's has a particularly distinguished reputation in the humanities, law, the sciences (including a wide range of health areas such as psychiatry, medicine, nursing and dentistry) and social sciences including international affairs. It has played a major role in many of the advances that have shaped modern life, such as the discovery of the structure of DNA and research that led to the development of radio, television, mobile phones and radar.

King's College London and Guy's and St Thomas', King's College Hospital and South London and Maudsley NHS Foundation Trusts are part of King's Health Partners. King's Health Partners Academic Health Sciences Centre (AHSC) is a pioneering global collaboration between one of the world's leading research-led universities and three of London's most successful NHS Foundation Trusts, including leading teaching hospitals and comprehensive mental health services. For more information, visit: www.kingshealthpartners.org.

King’s £600 million campaign, World questions|KING’s answers, has delivered huge global impact in areas where King’s has particular expertise. Philanthropic support has funded new research to save young lives at Evelina London Children’s Hospital; established the King’s Dickson Poon School of Law as a worldwide leader in transnational law; built a new Cancer Centre at Guy’s Hospital; allowed unique collaboration between leading neuroscientists to fast-track new treatments for Alzheimer’s, Parkinson’s, motor neurone disease, depression and schizophrenia at the new Maurice Wohl Clinical Neuroscience Institute; created the Cicely Saunders Institute: the first academic institution in the world dedicated to palliative care, and supported the King’s Sierra Leone Partnership in the Ebola crisis. Donations provide over 300 of the most promising students with scholarships and bursaries each year. More information about the campaign is available at www.kcl.ac.uk/kingsanswers.

Company info
Mini-site
KINGS COLLEGE LONDON
Telephone
+(44)02078365454
Location
STRAND
LONDON
WC2R 2LS
United Kingdom

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