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Postdoc Position in Cardiac Cellular Electrophysiology and Mechanics

Employer
MASARYK UNIVERSITY
Location
Brno, Czech Republic
Closing date
31 Jan 2024

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Department: Markéta Bébarová Research Group: Excitability and its Disorders – Faculty of Medicine
Deadline: 31 Jan 2024
Start date: April 2024 or upon agreement
Job type: full-time
Job field: Science and research

Medical Faculty of Masaryk University, Brno, Czech Republic invites excellent scientists to apply for

POSTDOC POSITION in 

Cardiac Cellular Electrophysiology and Mechanics

Description:

Adequate electrical activity is vital for the proper mechanical function of the heart. Its disturbances resulting in arrhythmias are the basis of myocardial dysfunction in various cardiac pathologies. Our research group is working at the Department of Physiology, Faculty of Medicine, Masaryk University (MU; Brno, Czech Republic; https://www.med.muni.cz/o-fakulte/organizacni-struktura/pracoviste/fyziologicky-ustav/vyzkumna-skupina-markety-bebarove). We currently mostly focus on analysis of the genetic base of idiopathic ventricular fibrillation (including genetic variants in hERG and RYR2), using both electrophysiological techniques (whole cell patch clamp and microelectrode array techniques) and optical analysis of cardiomyocyte contraction and Ca2+ transient. These studies proceed in tight cooperation with clinical cardiologists and geneticists from the University Hospital Brno. The experiments are performed on cell lines expressing human cardiac ionic channels as well as on patient-specific cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) that are prepared in cooperation with our colleagues at the Faculty of Science, MU. Better maturation of hiPSC-CMs (for example regular pacing and mechanical stretch of the cells during their differentiation) is also our goal.

The successful candidate should:

  • be a researcher who has received a PhD or its equivalent within the last 7 years
  • be a researcher who has worked at least 2 whole years in the last 3 years outside the territory of the Czech Republic in the field of research with a working time of at least 0.5 full-time equivalent, or who has been PhD student (or equivalent) abroad
  • have a publishing record – in the last 3 years at least 3 publication outputs (“articles”) above the field median (at least 2 of them in Q1) registered in the Thomson Reuters Web of Science

Specific criteria:

  • have experience in the field of cellular electrophysiology (patch clamp and/or multielectrode array techniques) (an advantage)
  • have experience with research projects (an advantage)
  • have excellent communication skills and teamwork

MU offers the opportunity to get:

  • initial appointment for 2 years
  • an interesting job in a dynamically-expanding university area
  • diverse and challenging work in an excellent research environment
  • a professional team and pleasant working conditions
  • interaction with leading scientists in an inspiring, internationalised environment
  • a welcome service for the successful candidate and his/her family

The application should include:

  • a CV including a list of publications
  • a diploma (recognition for diplomas from foreign institutions)
  • a cover letter, including a description of a) your most important research contributions, why your research is important and what impact it has had, b) your research interests and career aspirations, and c) why are you interested in this position
  • contacts for two referees who can provide insights into your qualifications
  • documents proving the candidate has worked at least 2 whole years in the last 3 years outside the territory of the Czech Republic and/or a PhD diploma from a foreign institution

Anticipated start date: The position is available from April 2024

The submission deadline is 31st January 2024

How to apply:

Please use the "E-Application" link below. After submitting your application, you will receive an automatic confirmation of acceptance via email. For more information, contact doc. MUDr. Marketa Bebarova, Ph.D. by e-mail: mbebar@med.muni.cz

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