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Lecturer/Senior Lecturer in Nucleic Acid Therapeutics (Medicines Development)

Employer
KINGS COLLEGE LONDON
Location
London (Greater)
Salary
Grade 7:£ 48,737 – £57,353 per annum Or Grade 8: £58,949 – £67,673 per annum
Closing date
11 Apr 2023

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Academic Discipline
Clinical, Pre-clinical & Health
Job Type
Academic Posts
Contract Type
Permanent
Hours
Full Time

Job Details

Job description

We are seeking a motivated Lecturer / Senior Lecturer to join our Medicines Development research group at the Institute of Pharmaceutical Science (IPS). 

 

We encourage applicants who have an expanding research profile and a proclivity for curiosity driven, perceptive research that will enhance the world-class research portfolio of the School of Cancer and Pharmaceutical Sciences and King’s Health Partners clinical academic groups of Pharmaceutical Science.  

 

IPS academics have expertise in the areas of pharmaceutical formulation and analysis, delivery across biological barriers, theranostic nanomedicines, enabling technologies, medicinal/bioinorganic/bioanalytical chemistry, biophysics, microbiology, systems biology, neurodegenerative diseases, pharmacology, vascular biology and inflammation. These are linked by cross-cutting themes in cancer diagnostics and therapeutics, antimicrobials and respiratory medicines. 

 

In Medicines Development research group, we build on understanding of drugs to develop medicines of high safety and efficacy. We invite applicants who can capitalise on the rapidly developing Nucleic Acid Therapeutics (NAT) capabilities and opportunities. The applicant is expected to bring expertise in enabling technologies for NAT delivery to the Medicines Development and Drug Discovery research groups and contribute to the healthcare missions identified in the Life Sciences Vision at King’s College London (KCL). 

 

We welcome applications from scientists with backgrounds in NAT chemistry, biology, drug delivery, pharmaceutical technology, pre-clinical or clinical translations of NATs.  We welcome imaginative and interdisciplinary applicants who can move our ambitions forward by pursuing new opportunities for laboratory research programmes. There is a particular opportunity to enhance collaborations with the Centre for the GMP manufacture of Investigational Medicinal Products, Centre for Gene Therapy & Regenerative Medicine, King’s Centre for Lung Health and Regenerative Biomaterials research at KCL. 

 

The applicant should have a strong, fundable research area that fits with the School of Cancer and Pharmaceutical Sciences and has obvious potential for collaboration with researchers across the School, the Faculty, King’s, the UK and internationally. 

 

An inclusive workplace delivers greater impact and we are looking for an individual who will help evolve our welcoming, vibrant, and inspiring environment. A key part of our ethos is equality, with a dynamic and fulfilling culture for all and an emphasis on tackling under-representation of female and minority ethnic researchers in science. 

 

The role requires a skilled educator to teach undergraduate and postgraduate students in the field of Pharmaceutical Science and embed within the existing teaching structure of Pharmacy UGT/PGT Programmes at KCL. 

 

This post will be offered on an indefinite contract  

This is a full-time  post

 

Key responsibilities

•       Deliver research excellence and high-quality education, as a principal research investigator, helping to shape the future of IPS and embed a supportive, collegiate culture. 

 

•       Define and lead research in development of nucleic acid-based medicines for diagnostic and therapeutic applications, securing funding to develop a highly respected, international, research programme. This will include productive collaborative links in academia and/or industry and with colleagues in IPS, across King’s, the UK and internationally. 

 

•       Take responsibility for developing the talent of students and research staff to ensure their effective career progression.  

 

•       Enhance the education and experiences of our undergraduate and postgraduate students, delivering appealing, up-to-date teaching in pharmaceutical science (pharmaceutics, dosage form design and manufacture, drug delivery) and contributing to the development of our curricula and teaching and assessment methods.  

 

•       Provide visionary and proactive leadership in developing and expanding nucleic acids therapeutics research capability within IPS and Faculty of Life Science and Medicine. 

 

•       Lead in seeking external funding for research activities and projects, individually or with other PIs at IPS and beyond, with an ability to identify high-quality grant capture opportunities. 

 

•       Guided by the department safety committee and practices, be responsible for the health and safety of yourself and others. 

 

•       Undertake a proportionate level of administration associated with research and teaching in higher education.

 

The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.  

Skills, knowledge, and experience 

Essential criteria (Senior Lecturer)  

1.      First Degree or Masters in relevant subject 

2.      PhD in chemistry, biology, chemical or bioengineering, material science, pharmacy or a related subject 

3.      An externally-recognized international reputation for research evidenced, for example, by invited presentation of research at international conferences or publications in scientific journals 

4.      A track record of attracting research funding in relevant area  

5.      Evidence of developing new knowledge, innovative research and broadening the boundaries of drug delivery, medicines development, biotherapeutics, nucleic acid therapeutics (NATs) or advanced therapies. 

6.      Ability to teach relevant subjects at undergraduate and postgraduate levels 

7.      Highly effective oral and written communication skills, to convey conceptual and complex ideas and information, alongside good organisational and administrative skills 

8.      Proactive in creating and developing interactions and collaborations with colleagues 

9.      Ability to lead and function within a team and to plan and prioritise workload 

10.    Evidence of academic leadership 

 

Desirable criteria (Senior Lecturer) 

1.      Research in chemical or biological modifications of NATs to improve their stability and targeting/biodistribution in vivo, improvement in formulation strategies including lipids, biomaterials, bioprinting etc, in vivo tracking and imaging  

2.      Experience in applying NATs to one of the following is desirable: cancer, lung diseases, brain, heart and infectious diseases  

3.      Experience in aptamers, siRNA, shRNA, mRNA design and delivery  

4.      Experience in the biological and chemical analysis and quality control of NAT  

5.      Experience in chemical synthesis of ionisable lipids  

6.      Supervision of undergraduate projects and postgraduate research students. 

7.      Experience of curriculum design. 

8.      Teaching qualifications 

 

Essential criteria (Lecturer) 

1.      First Degree or Masters in relevant subject 

2.      PhD in chemistry, biology, chemical or bioengineering, material science, pharmacy or a related subject 

3.      Postdoctoral experience 

4.      Evidence of developing new knowledge, innovative research and broadening the boundaries of drug delivery, medicines development, biotherapeutics, nucleic acid therapeutics (NATs) or advanced therapies 

5.      Ability to teach relevant subjects at undergraduate and postgraduate levels 

6.      Highly effective oral and written communication skills, to convey conceptual and complex ideas and information, alongside good organisational and administrative skills 

7.      Proactive in creating and developing interactions and collaborations with colleagues 

8.      Ability to lead and function within a team and to plan and prioritise workload 

9.      Potential to provide academic leadership 

 

Desirable criteria (Lecturer) 

1.      Success in obtaining research grant funding 

2.      Research in chemical or biological modifications of NATs to improve their in vivo stability and delivery, improvement in delivery strategies including lipids, biomaterials, bioprinting etc, in vivo tracking and imaging. 

3.      Experience in applying NATs to one of the following is desirable: cancer, lung diseases, antimicrobials, brain, heart and infectious diseases.  

4.      Experience in aptamers, siRNA, shRNA, mRNA design and delivery. 

5.      Experience in chemical synthesis of ionisable lipids. 

6.      Invited contributions to international research conferences. 

7.      Supervision of undergraduate projects and postgraduate research students. 

8.      Teaching qualifications

Company

King's College London is one of the top 20 universities in the world and among the oldest in England. King's has more than 27,600 students (of whom nearly 10,500 are graduate students) from some 150 countries worldwide, and some 6,800 staff.

King's has an outstanding reputation for world-class teaching and cutting-edge research. In the 2014 Research Excellence Framework (REF) King’s was ranked 6th nationally in the ‘power’ ranking, which takes into account both the quality and quantity of research activity, and 7th for quality according to Times Higher Education rankings. Eighty-four per cent of research at King’s was deemed ‘world-leading’ or ‘internationally excellent’ (3* and 4*). The university is in the top seven UK universities for research earnings and has an overall annual income of more than £684 million.

King's has a particularly distinguished reputation in the humanities, law, the sciences (including a wide range of health areas such as psychiatry, medicine, nursing and dentistry) and social sciences including international affairs. It has played a major role in many of the advances that have shaped modern life, such as the discovery of the structure of DNA and research that led to the development of radio, television, mobile phones and radar.

King's College London and Guy's and St Thomas', King's College Hospital and South London and Maudsley NHS Foundation Trusts are part of King's Health Partners. King's Health Partners Academic Health Sciences Centre (AHSC) is a pioneering global collaboration between one of the world's leading research-led universities and three of London's most successful NHS Foundation Trusts, including leading teaching hospitals and comprehensive mental health services. For more information, visit: www.kingshealthpartners.org.

King’s £600 million campaign, World questions|KING’s answers, has delivered huge global impact in areas where King’s has particular expertise. Philanthropic support has funded new research to save young lives at Evelina London Children’s Hospital; established the King’s Dickson Poon School of Law as a worldwide leader in transnational law; built a new Cancer Centre at Guy’s Hospital; allowed unique collaboration between leading neuroscientists to fast-track new treatments for Alzheimer’s, Parkinson’s, motor neurone disease, depression and schizophrenia at the new Maurice Wohl Clinical Neuroscience Institute; created the Cicely Saunders Institute: the first academic institution in the world dedicated to palliative care, and supported the King’s Sierra Leone Partnership in the Ebola crisis. Donations provide over 300 of the most promising students with scholarships and bursaries each year. More information about the campaign is available at www.kcl.ac.uk/kingsanswers.

Company info
Mini-site
KINGS COLLEGE LONDON
Telephone
+(44)02078365454
Location
STRAND
LONDON
WC2R 2LS
United Kingdom

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