The Biotechnology Center (BIOTEC) (https://tu-dresden.de/cmcb/biotec) and its partner institutions, Center for Molecular Bioengineering (B CUBE) and the Center for Regenerative Therapies Dresden (CRTD), are equipped with state-of-the-art facilities for Molecular Bioscience research (https://tu-dresden.de/cmcb/bcube/forschung-technologie/technologieplattform). They are part of a rich and collaborative environment that includes the Faculty of Mathematics, the Carl Gustav Carus Faculty of Medicine, the Max-Planck- Institute of Molecular Cell Biology and Genetics (MPI-CBG) and the Leibniz Institute for Polymer Research Dresden (IPF). For TU Dresden (TUD) diversity is an essential feature and a quality criterion of an excellent university. Accordingly, we welcome all applicants who would like to commit themselves, their achievements and productivity to the success of the whole institution. 

At the Biotechnology Center (BIOTEC), an Institute of the Center for Molecular and Cellular Bioengineering (CMCB), the Research Group Biomedical Genomics offers a position as 

Research Associate / Postdoc Computational Single Cell Omics (m/f/x)
(subject to personal qualification employees are remunerated according to salary group E 13 TV-L) 

starting June 1, 2023. The position is limited to 2 years. An extension to approximately 4 years is anticipated. The period of employment is governed by the Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz-WissZeitVG). The position offers the chance to obtain further academic qualification.

Tasks: Injury in an organism leads to major changes in cellular organization and alterations of gene regulatory programs. Such alterations now become visible in unprecedented detail with single cell technologies. To strengthen our diverse team, we are looking for a postdoctoral fellow to study single cell multi-omics as part of the DFG sequencing project „The unique regenerative state of spinal progenitors“. We will investigate single-cell behaviour in zebrafish in the context of spinal cord regeneration using single cell omics, such as simultaneous single cell RNA- and ATAC-seq. Using multi-omics data integration and machine learning, we will investigate behaviours and gene-regulatory network changes in spinal progenitor cells in response to spinal cord injury. The project is a collaboration between the Chair of Neural Development and Regeneration (Prof. Catherina Becker) and the computational Research Group Biomedical Genomics (Dr. Anna Poetsch), where this position will be based. The successful candidate will have the opportunity to receive training in cutting-edge methods in multi-omics data integration and the possibility to learn and apply machine learning and deep learning methods on genomics data. 

Requirements: 

• excellent university and PhD degree with experience in molecular biology, computational biology, genetics, genomics, or equivalent scientific background with an excellent understanding of genome biology;
• comprehensive programming experience in python and/or R;
• demonstrable experience in multi-omics and/or single cell omics data analysis;
• very good interpersonal and communication skills; in particular, the ability to effectively work in a diverse, collaborative and interdisciplinary research environment;
• fluency in English - written and oral (German is not required).

The BIOTEC/CMCB is a renowned interdisciplinary and international research institute of the TUD that boasts a collaborative spirit and cutting-edge technology platforms, including one of the national genome centres and cutting-edge High Performance Computing resources. The city of Dresden provides numerous chances for scientific exchange and collaboration.

TUD strives to employ more women in academia and research. We therefore expressly encourage women to apply. The University is a certified family-friendly university and offers a Dual Career Service. We welcome applications from candidates with disabilities. If multiple candidates prove to be equally qualified, those with disabilities or with equivalent status pursuant to the German Social Code IX (SGB IX) will receive priority for employment.

Please submit your comprehensive application including the usual documents (including a letter of motivation, your CV including a list of publications, transcripts of records, and contact details for 2-3 academic references) by April 13, 2023 (stamped arrival date of the university central mail service applies) preferably via the TU Dresden SecureMail Portal https://securemail.tu-dresden.de by sending it as a single pdf-document to sabine.zeissig@tu-dresden.de, or to: TU Dresden, BIOTEC, Forschungsgruppe Biomedizinische Genomik, Frau Dr. Anna Poetsch, Helmholtzstr. 10, 01069 Dresden, Germany. Please submit copies only, as your application will not be returned to you. Expenses incurred in attending interviews cannot be reimbursed.

Reference to data protection: Your data protection rights, the purpose for which your data will be processed, as well as further information about data protection is available to you on the website: https://tu-dresden.de/karriere/datenschutzhinweis.