Research Fellow, Bioinformatician - Cancer Science Institute

Job Description

A postdoctoral position is available immediately in A/Prof Polly Chen’s groups for a highly motivated PhD graduate with experience in Bioinformatics (computational genomics). The focus of A/P Polly Chen’s lab is on the transcriptome-wide identification of RNA changes (e.g., RNA editing, alterative splicing, altered protein-RNA interactions, etc) in tumors and functional investigation of these changes in cancer.

Duties And Responsibilities

Candidates should have strong background in bioinformatics, genomics/transcriptomics, computer science, statistics, or other related fields. Those who are interested in computational genomics and transcriptomics, particularly in analysis and integration of various genomics/transcriptomics data, are encouraged to apply. The successful candidate will analyze and integrate in-house NGS datasets (bulk and single-cell RNA-seq, spatial transcriptomics, DNA-seq, eCLIP-seq, MeDIP-seq, etc) and also utilize publicly available genomic/transriptomics/clinical data sets to identify novel biological biomarkers/patterns and regulatory mechanisms.

Candidates are required to have a strong quantitative and statistics background, as well as strong programming skills (e.g. Python, Perl, C, C++, Java, R, or other related programming knowledge), and excellent skills in handling genomic, transcriptomic and proteomic databases. Experience in analyzing RNA editing, alternative splicing, RNA binding sites using the bulk and single-cell RNA-seq, eCLIP-seq, spatial transcriptomic data is a plus.

Qualifications

• A PhD graduate with relevant experience in areas of computational biology/bioinformatics
• Extensive knowledge and experience in working with a variety of NGS datasets, pipeline development and algorithm development
• Strong publication track record, indicated by first author publications in high quality journals
• Strong analytical skills and programming skills
• Ability to write/contribute to research articles, grants and keep meticulous notes/proper scientific documentation
• Strong interpersonal, written and oral communication skills
• A strong team focus and ability to work independently

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Taking into consideration the health and well-being of our staff and students and to better protect everyone in the campus, applicants are strongly encouraged to have themselves fully COVID-19 vaccinated to secure successful employment with NUS.