Full-time Research and Teaching Position in Medicinal Chemistry

Immunotherapies have brought about a paradigm shift in cancer treatment from the cancer itself to the host immune system, and have produced unprecedented responses with complete remissions to advanced and metastatic stages of the disease for a subset of patients. Response rates remain low, however, mainly due to the immunosuppressive environments of many tumors. Local therapies capable of activating innate immunity pathways, stimulating tumor inflammation, immune infiltrates and priming the adaptive immune system are urgently needed and considered one of the major strategies to enable immunotherapies to be effective in more patients and cancer types. STING, the main regulator of the interferon response, is one of the major targets for achieving this goal, but current compounds face major limitations due to their systemic toxicity. The present project will address this problem by synthesizing novel STING agonists that respond to stimuli and are selectively activated at the tumor site. Will be done in collaboration with American universities on the East Coast, the candidate will be asked to travel.

Main Research Field : Medicinal Chemistry

Sub Research Field : Chemistry, Biology

Required educational level: Master level  in (Chemistry or Pharmaceutical Sciences) 

Required Languages :

Fran ais : Good

English : Good

Interested ?

For more information, please contact Prof. Gilles BERGER (E-mail: gilles.berger@ulb.be)

Applications must be sent by e-mail to the rectorate of the Universit Libre de Bruxelles (rectrice@ulb.be ) and to the faculty deanship ( Doyen.ne.pharma@ulb.be and daf.pharma@ulb.be.).

They must include the following :

• a motivation letter
• a Curriculum vitae including a list of publications :

1. if you want you can complete a standard form via our website at https://www.ulb.be/fr/documents-officiels/completer-votre-cv-en-ligne .  Once completed, it must be downloaded and attached to the application file.

• a note on the applicant s PhD research project (4 pages)
• two letters of reference

Equal opportunities policy

ULB's personnel management policy is geared towards diversity and equal opportunities.

We recruit candidates on the basis of their skills, irrespective of age, gender, sexual orientation, origin, nationality, beliefs, disability, etc.

Would you like to be provided with reasonable accommodation in the selection procedure because of a disability, disorder, or illness?  Please contact Marie Botty, the person in charge of diversity aspects for the academic and scientific staff (marie.botty@ulb.be). Be assured of the confidentiality of this information.

More details on the ULB gender and diversity policy are available at https://www.ulb.be/en/about-ulb/gender-equality-at-ulb. 

You will find all the regulations relating to research careers on our site at http://www.ulb.ac.be/emploi/academique.html.

Reference : 2023/S095

Application deadline : 31/05/2023

Start date: 01/10/2023