Post Doc Position in cardiac modelling V-Smart Project

6 days left

Location
Pessac, Gironde, France
Posted
07 Mar 2023
End of advertisement period
30 Mar 2023
Ref
Euraxess_71868
Contract Type
Temporary
Hours
Full Time

You want to join a leading team on an innovative project in heart modelling?

 

Join the Institut de Rythmologie et de Mod lisation Cardiaque (IHU Liryc) at the University of Bordeaux!

 

In particular, the Institute is organized into clinical research teams that work closely with basic research teams.

Within the modelling division, which cooperates with INRIA, we develop new numerical models for modelling and simulation of the electrical and mechanical activity of the heart. The work of our experts in mathematics and computer science allows us to better understand the mechanisms of rhythm disorder.

 

As part of the V-Smart project, funded by the National Research Agency (ANR), we are looking for a Post-Doc.

 

This project starts from the premise that the mechanical consequences of cardiac scarring, in addition to electro-physiological remodelling, greatly increase the risk of arrhythmogen.

To demonstrate this, we combine biological experiments with computer simulations.

The biological experiments will provide functional data for parameterizing the mechanical-electrical feedback. With this new physiological knowledge, custom electromechanical cardiac models of patients with infarction at unprecedented resolution will be created, and potential therapies will be studied in silico.

 

Main activities:

 

In this context, your main mission will be to segment images and create finite element meshes. This will allow to run the simulations on supercomputers (HPC) and analyze the results.

 

As such you:

 

Conduct a study on the relationship between scarring and arrhythmias

Build finite element models and mathematical models

Draw studies to better understand how scars disrupt developed mechanical forces affecting electrical activity and triggering cardiac arrhythmias

Conduct virtual simulations and experiments on HPC high performance computing resources and write down tools to analyze results

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