Senior Research Fellow in Tuberculosis

Innate Immunology

Location:  Southampton General Hospital
Salary:   £42,155 to £53,353 Per annum
Full Time Fixed Term (31/05/2025)
Closing Date:  Wednesday 08 February 2023
Interview Date:   To be confirmed
Reference:  2164423FC

Senior Research Fellow in the Tuberculosis Research Group in the School of Clinical and Experimental Sciences (CES), Faculty of Medicine, University of Southampton

Applications are invited for this full-time senior post-doctoral research fellow with the tuberculosis research group, funded by an MRC project grant entitled “Investigating local determinants of outcome in human tuberculosis”.   This study utilises the 3D biomimetic model of TB developed by the Southampton group to study the host-pathogen interaction.  The post-holder will work closely alongside Drs Liku Tezera and Paul Elkington, and will combine 3D cell culture modelling with imaging and immunological readouts to study the effect of interventions.  The biomimetic model has provided diverse insights (eg JID 2015, eLife 2017, mBio 2017, eLife 2020, JCI 2021, JCI 2021) and the current programme will bring additional technologies to study infection.  Candidates should have a PhD in immunology or cell biology and a track record of research excellence. Candidates with a PhD in infection, molecular biology, biochemistry, transcriptomics or a relevant field with experience in cell culture and immunoassays will also be considered.  We are seeking a candidate with an outstanding previous track publication record, including top rated international peer review publications, and a broad skill set including multiparameter flow cytometry, single cell RNAseq and emerging tissue imaging methodologies.  The key attributes are teamwork, enthusiasm for interdisciplinary research and interpersonal skills.   The post is funded for 2 ½ years initially.

The successful candidate will join a vibrant multidisciplinary team of researchers in the Academic Unit of Clinical & Experimental Sciences (CES), Section of Innate Immunity.  The University of Southampton (UoS) is a world-class research-intensive Russell Group university, and central themes of the Faculty of Medicine and NIHR Biomedical research centre are Infectious diseases, Respiratory Medicine and Interdisciplinary research.

We are proactive in fostering a culture of inclusion, respect, and equality of opportunity. We select candidates based on merit and ability and aspire to thrive in the diversity of our workforce.  We welcome applications from all candidates with an interest in the role and those who are committed to helping us create an inclusive work environment. We encourage applications from candidates from Black, Asian, and Minority Ethnic communities, people who identify as LGBTQ+, and people with disabilities.  

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Application Procedure 

The application deadline is midnight on the closing date stated above. If you need assistance, call Recruitment on  +44 (0) 23 8059 2750, or email recruitment@soton.ac.uk. Quote the advert reference on all correspondence.