Applications are invited for a temporary post of a UCD Post-doctoral Research Fellow Level 1 or 2 within UCD Conway Institute & SPHPSS.

Applications are invited for a very dynamic Post-doctoral Research Fellow Level 1 or 2 to work as part of our SFI Frontiers Programme `Diet, Metabolism and Innate Immune Training' team with Prof Helen Roche's Nutrigenomics Team at UCD Conway Institute https://people.ucd.ie/helen.roche.

`Diet, Metabolism and Innate Immune Training' is a collaborative project with Dr Fred Sheedy's team in TCD. The project is designed to investigate the interaction between diet, microbiota diversity and metabolism on innate immune function in metabolic disease (non-alcoholic fatty liver disease (NAFLD)).

The UCD Team are focused on human studies, which complement the pre-clinical work at TCD. The post is to provide high-level scientific knowledge, experimental and management skills to support UCDs contribution to this collaborative programme. Specific knowledge in relation to the role of nutrition and/or metabolic health within the context of inflammation is essential.

We are comparing the immune-metabolic phenotypes of NAFLD versus NASH. The study will also characterise the effect of novel dietary interventions on the gut microbiome, to understand cross-talk between metabolism and inflammation in man. Complimentary in vivo animal feeding / immune-metabolic studies (completed in TCD) will explore mechanisms.

Specific expertise in human metabolic phenotyping, ex vivo immune cell characterisation, cellular metabolism, Seahorse, RT-PCR, western blot, metabolic and inflammatory signalling and/or the gut microbiome, is required. Candidates should be highly self-motivated and enthusiastic, who interact well within a large research team. They should hold a PhD in nutrition, biochemistry, immunology or related disciplines; have excellent research skills as evidenced by strong publications, allied with exceptional project management and interpersonal skills.

In addition to the principal duties and responsibilities below, The post-holder will have responsibility for a number of specific areas, including those outlined below:

• Manage the day-to-day operation of the project within the Nutrigenomics Group.
• Organise scientific meetings to present and discuss of on-going analysis / research.
• Prepare of annual progress & scientific reports.
• Lead authorship of high-impact peer review scientific publications.
• Disseminate findings to the scientific and public audiences.

This is a research focused role, where you will conduct a specified programme of research supported by research training and development under the supervision and direction of a Principal Investigator. The primary purpose of the role is to further develop your research skills and competences, including the processes of publication in peer-reviewed academic publications, the development of funding proposals, the mentorship of graduate students along with the opportunity to develop your skills in research led teaching.

POST DOC LEVEL 1 Salary Range: 41,209 - 47,477 per annum or

POST DOC LEVEL 2 Salary Range: 48,813 - 53,091 per annum

Appointment on the above range will be dependent upon qualifications and experience.

Closing date: 17:00hrs (local Irish time) on 6th March 2023.

Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications. UCD do not require assistance from Recruitment Agencies. Any CV's submitted by Recruitment Agencies will be returned.

Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.