Research Fellow in Immunology

Molecular and Cellular biosciences

Location:  Southampton General Hospital
Salary:   £33,314 to £40,931 Per annum
Full Time Fixed Term (36 months)
Closing Date:  Friday 03 February 2023
Interview Date:   To be confirmed
Reference:  2119122BJ

Job description

The Gwyer Findlay lab investigates how neutrophils affect T cell phenotype. Our work sits at the interface of immunology and inflammation biology and we use a variety of methods in our studies – immunology, molecular biology, computational biology and imaging.

In this project we are aiming to understand how neutrophils alter T cell cytokine production. We have previously shown that when neutrophils release antimicrobial peptides, they enter nearby T cells and profoundly alter T cell cytokine production. In particular, they affect the production of the IL-17 family of cytokines. In this project we will work out how this occurs. Through culture of mouse and human T cells, flow cytometry, RNA and ATAC sequencing and imaging, we will examine the signalling pathways induced by neutrophil peptides and how they lead to differential IL-17 production.

You will hold a PhD in immunology, biology, or a related discipline.  Highly organised and driven, you will demonstrate initiative and problem-solving skills. You will have experience in and knowledge of T cell immunology, cell culture, and flow cytometry.

Applications will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification.  The title of Research Fellow will be applied upon completion of PhD.  Prior to the qualification being awarded the title of Senior Research Assistant will be given.

What we can offer you

• a world-class research environment
• access to mentoring, career development and networking across the University and beyond
• a personalised training and development plan including external training courses and attendance at conferences
• a friendly, supportive lab environment

As a founding signatory of the Athena SWAN charter, and holder of a silver award, we’re committed to improving equality. We aim to create an environment where everyone can thrive and are proactive in fostering a culture of inclusion, respect and equality of opportunity. We believe that we can only truly meet our objectives if we are reflective of society, so we are passionate about creating a working environment in which you are free to bring your whole self to work. 

As well as additional benefits that will make your life easier, such as a generous holiday allowance and additional university closure days, we will help you find a good work-life balance with flexible, or even part-time, working hours. We will support your long-term future too, with access to the Universities Superannuation Scheme (USS)*, subsidised health and fitness facilities and a range of discounts. 

For additional information or informal enquiries before submitting your application, please email Emily Findlay at e.gwyerfindlay@soton.ac.uk.

Application Procedure

You should submit your completed online application form at https://jobs.soton.ac.uk. The application deadline will be midnight on the closing date stated above. References are requested along with your application. This reference system is automated so please ensure you provide the correct email address and allow time for these to be received, prior to the close date, to assist the department with shortlisting. 

If you need any assistance, please call Sian Gale (Recruitment Team) on +44 (0) 23 8059 2750, or email recruitment@soton.ac.uk. Please quote reference 2119122BJ on all correspondence.