QUEENS UNIVERSITY BELFAST

Postdoctoral Research Fellow in Molecular Biology

Location
Belfast, Northern Ireland
Salary
£35,333 - £38,592 per annum
Posted
21 Sep 2022
End of advertisement period
03 Oct 2022
Ref
22/110206
Contract Type
Fixed Term
Hours
Full Time

Job description

The School of Medicine, Dentistry & Biomedical Sciences (MDBS) at Queen’s University Belfast, is currently seeking to appoint an exceptional candidate to the post of Postdoctoral Research Fellow.

The Tiwari Lab (www.tiwarilab.com) is looking for a Postdoctoral Research Fellow in Molecular Biology. Our team works on employing functional genomics approaches to decode gene regulatory networks underlying brain development and function as well as understand how these are disrupted in disorders.

Epilepsy is a common and serious brain disease characterized by recurrent seizures. The recruited postdoc will derive and analyse state of the art genomics data derived from patients to reveal what happens to transcriptome in the intact human brain during epileptiform activity and how this is regulated via epigenetic states. This innovative, ground-breaking research study brings together world-leading experts to generate a deeper understanding of the relationship between epileptiform activity and the molecular landscape in the human brain. This will improve understanding of the mechanistic basis of these biomarkers and help design novel transcript- and epigenome-targeting therapeutics in the future. Depending on the interest, it is also possible to be involved in the bioinformatics analysis.

The following publications from Tiwari lab can be referred to for learning about the ongoing research program and assess a fit:

Nature Cell Biology, 2022, Aug 24, 1265–1277; Nature Communications. 2022 Jul 27;13(1):4320; Genes & Development, 2020, Sep; 34(17-18):1190-1209; Nature, 2019, Mar; 567(7746):113-117; Cell Stem Cell, 2018, Oct 4; 23(4):557; Nature Communications, 2017 Nov 15;8(1):1523; The EMBO Journal, 2016 Jan 4;35(1):24-45; J Cell Science, 2015 Dec 1;128(23):4380-94; The EMBO Journal, 2015 Aug 13;34(16):2162-81; Genome Research, 2015 Sep;25(9):1309-24; Nature Communications, 2013, Sep 27; 4:2478; Cancer Cell, 2013, 23, 768-783; PNAS, 2012 Apr 17;109(16): E934-43; Nature Genetics, 2012 Jan; 18;44(1):94-100;  Nature, 2011 Dec 14;480(7378):490-5.

The successful candidate must have, and your application should clearly demonstrate you have:

  • Have or about to obtain a PhD in Molecular Biology or Biochemistry or Epigenetics or Neurobiology or Genetics or related areas.
  • 3 years recent relevant work experience (includes PhD) to include:
    • Gene regulation
    • Cell culture
    • Basic molecular biology assays such as RNA extraction, qPCR, Immunoblot analysis, IP assays.
  • At least one recent high-quality, first author, original research publication in a reputable peer-reviewed journal, commensurate with career stage.

Please note the above are not an exhaustive list. For further information about the role including the essential and desirable criteria please click the Candidate Information link below.

This post is fixed term for 12 months, with the possiblilty of extension.

Fixed term contract posts are available for the stated period in the first instance but in particular circumstances may be renewed or made permanent subject to availability of funding.

At Queen’s our people are at the heart of everything we do. As a staff member you will become part of a vibrant organisational culture, which will provide you with the opportunity to achieve your full potential and enhance your career through a continuous focus on learning and development. 

We offer an excellent employment package that includes:

  • Great terms & conditions
  • Pension schemes
  • Family-friendly initiatives
  • Career development opportunities
  • Support for health & mental wellbeing
  • Generous holiday entitlement of 8 weeks a year (made up of 23 days annual leave, 10 closure days and 9 bank holidays)

Queen’s University is committed to promoting equality of opportunity to all. We have created an inclusive culture by establishing staff networks such as iRise (Race) and PRISM (LGBTQ+) which help us progress equality. 

We also subscribe to Equality Charter Marks such as the Diversity Charter Mark NI in addition to Athena Swan. For further information on our commitment to Equality, Diversity and Inclusion, please visit:  www.qub.ac.uk/diversity; www.qub.ac.uk/qgi and www.qub.ac.uk/sites/StaffGateway/StaffNetworks/ 

Informal enquiries may be directed to Dr Effie Kostaeli at e.kostareli@qub.ac.uk 

Candidate Information
About the WWIEM
About the Tiwari Lab
Attrative Reward Package
Information for International Applicants

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