Applications are invited for a Temporary post of a UCD Post-doctoral Research Fellow Level 1 within UCD School of Medicine/Charles Institute of Dermatology

Diversity of human skin colour is regulated at intrinsic (i.e., constitutive) and extrinsic (i.e., facultative) levels. The former refers to an individual's genetically-determined amount/type of melanin, while the latter refers to the sensitivity/propensity of our skin to respond to stimulated pigmentation (e.g., from hormones, UVR etc.). Importantly, human skin phototypes reflects relative activity, rather than absolute number, of melanocytes. As an interface tissue, human skin is subjected to a wide range of stimuli, some of which induce stable, reversible and/or heritable, changes in how genes function, in a way that does not result in DNA sequence change. Our knowledge of such `epigenetic' control of pigmentation in human skin is still in its infancy and is the focus of this project. We will ask if epigenetic regulation of human skin pigmentation at baseline is similar or different to stimulated pigmentation, and if different, whether differential regulation is influenced by particular epigenetic events.

This is a research focused role, where you will conduct a specified programme of research supported by research training and development under the supervision and direction of a Principal Investigator. The primary purpose of the role is to further develop your research skills and competences, including the processes of publication in peer-reviewed academic publications, the development of funding proposals, the mentorship of graduate students along with the opportunity to develop your skills in research led teaching.

Candidates must have an excellent knowledge and laboratory experience of mammalian epigenetics. They will also maintain accurate and comprehensive experimental records with excellent attention to detail; assist in preparing presentations and reports as required; maintain laboratory equipment and facilities, and other duties associated with the research project, of an occasional nature, which may be assigned by the Principal Investigator, Prof. Des Tobin.

PD1 Salary: €39,522 - €45,610 per annum

Appointment on the above range will be dependent on qualifications and experience

Closing date: 17:00hrs (local Irish time) on 7th October 2022

Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications. UCD do not require assistance from Recruitment Agencies. Any CV's submitted by Recruitment Agencies will be returned.

Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.