Post-doctoral Research Fellow
Applications are invited for a Temporary 4 year post of a UCD Post-doctoral Research Fellow Level 1 within UCD School of Biomolecular and Biomedical Science
Antimicrobial resistance (AMR) poses a major global risk to human health by causing death, disability, longer hospitalisations, and increased healthcare costs. Vaccines are ideally suited to tackle this problem, improving the lives of people worldwide. The All-island Vaccine Research and Training Alliance (AVACTA) is a hub of excellence aimed to develop effective vaccines against ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter cloacae), a group of bacteria that resist to practically all available antimicrobials, which are considered a major global threat.
Complementing vaccine development technologies, AVACTA will also tackle the challenges associated with vaccine hesitancy, developing implementable guidelines to improve vaccine uptake in Ireland and Northern Ireland. AVACTA will provide a unique interdisciplinary PhD program with cross-training in complementary areas of life-sciences, biotechnology, health psychology, public health, ethics, and communication to build capacity in vaccine design, development, and deployment on the island of Ireland. This post-doctoral fellowship project will focus on vaccines against three ESKAPE bacteria: Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa. No approved vaccines exist for the ESKAPE pathogens being targeted by AVACTA.
The UCD team have already identified panels of novel vaccine candidate antigens targeting three ESKAPE pathogens. This AVACTA project will focus on these existing panels of vaccine candidates with a view to developing a "Universal ESKAPE vaccine".
This is an exciting research focused role funded by the All-island Vaccine Research and Training Alliance (AVACTA), under the Higher Education Authority's North-South Research Programme. The successful candidate will conduct a specified programme of research supported by research training and development under the supervision and direction of a Principal Investigator. You will further develop your research skills and competences, including the processes of publication in peer-reviewed academic publications, the development of funding proposals, the mentorship of graduate students along with the opportunity to develop your skills in research led teaching.
In addition to the Principal Duties and Responsibilities listed below, the successful candidate will take a lead role in the following aspects of the research project:
- Screening our existing panels of ESKAPE pathogen vaccine antigens for common motifs;
- Evaluating T-cell responses to vaccine antigens;
- Examining antigen stability and characterisation;
- In collaboration with other partners, formulating lead vaccine antigens in nanoparticles or exploring approaches to maximise protective mucosal responses.
Fixed Salary: €39,522 per annum
Closing date: 17:00hrs (local Irish time) on 20th July 2022
Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.
UCD do not require assistance from Recruitment Agencies. Any CV's submitted by Recruitment Agencies will be returned.
Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/