Senior Research Technician
The King’s College London British Heart Foundation (BHF) Centre of Research Excellence is designed to nurture interdisciplinary collaborations and bench-to-bedside projects in cardiovascular research. The School of Cardiovascular and Metabolic Medicine & Sciences is a core constituent of the BHF Centre where the cardiovascular proteomics group is led by Prof. Manuel Mayr. The cardiovascular proteomics research group ( www.vascular-proteomics.com) has the latest mass spectrometry equipment, established computational infrastructure and high experience in proteomics and multi-omics research projects.
The research work of the group encompasses a wide variety of wet and dry lab activities. These include molecular and cellular biology experimentation and support in specialist techniques. The post holder with work alongside the Schools Professional Services team, providing high quality technical support and assisting in laboratory research activities. It is expected that 50% of the time will be spent on ensuring the smooth running in the labs, including ensuring a high standard of cleanliness and sustainability within the lab, producing sterile preparations and provisions, servicing and maintaining equipment, management of chemical and stock supplies, and ensuring compliance with health and safety procedures as directed by the department. It is expected that 30% of the time will be dedicated to scientific services which support experimental research including aseptic tissue collection, tissue and cell culture and isolation of primary neonatal and adult cardiac myocytes from both mice and rats. The rest of the time will be spent providing experimental support for molecular and cellular biology experiments and participating in School projects and activities as directed.
This post will be offered on an a fixed-term contract for 2 years. This is a full-time post - 100% full time equivalent.
• Provide in-depth knowledge of technical or scientific practices, methods and procedures gained through experience and/or formal education
• Support a range of technical activities, providing research support and scientific services where there are established standards and requirements for service
• Ensure the smooth day-to-day running of the labs, including equipment maintenance and resource management
• Actively participate in Continuing Professional Development and training initiatives, in line with the Technician Commitment
• Gain a strong understanding of the laboratory users’ requirements and appropriately align with changing priorities/needs
The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.
Skills, knowledge, and experience
The post requires a minimum level 4 qualification, plus work experience in a relevant technical/scientific post and knowledge and skills of a range of scientific practices and procedures applicable to the area of work. The successful applicant must demonstrate proven technical experience in a range of techniques in molecular biology, cell culture and histology, microscopy. The post holder must demonstrate an active commitment to professional development such as membership to a professional body, commitment to Continuing Professional Development and/or ongoing training or education activities.
1. Minimum level 4 qualification e.g. higher apprenticeship, HNC or other Level 4 award
2. Previous work experience in a relevant technical/scientific post
3. Extensive knowledge and skills gained through work experience in a relevant technical or scientific post
4. Expertise in molecular biology, cell culture and/or histology
5. Working knowledge and understanding of Laboratory Health and Safety Regulations (COSHH, GMO (contained use), etc.) governing the area of work
6. Good computer skills, numeracy skills and ability to apply learnt techniques to the work context
7. Good planning and organization skills, with ability to manage own workload and work with minimal supervision
8. Excellent communication skills, orally and in writing, along with strong interpersonal and collaborative skills
9. Understanding of methodologies and techniques with a knowledge of a range of technical or scientific practices, methods of procedures applicable to the work area
10. Knowledge of environmental impacts of laboratory work and an interest in reducing the negative impacts
11. Strong commitment to Continuing Professional Development and active engagement in ongoing training and learning activities
1. Experience working in a biological services unit, with a strong understanding of the Animals (Scientific Procedures) Act
2. Knowledge of Schedule 1 techniques, mutant colony breeding systems, and genotyping of transgenic mouse colonies
3. Experience in laboratory equipment maintenance and management of stock levels of consumables, supplies and in-house preparations
4. Experience of supervising/advising junior team members, giving feedback on performance levels and training/coaching where necessary
The applicant should be able and willing to provide additional support beyond core hours as required.
This post is subject to Disclosure and Barring Service and Occupational Health clearance.
Molecular Biology; Cellular Biology; Senior Research Technician