Research Fellow, Cancer Science Institute

17 Jun 2022
End of advertisement period
17 Jul 2022
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Fixed Term
Full Time

Job Description 


The position of Postdoctoral Research Fellow (RF) is available at the Cancer Science Institute of Singapore, National University of Singapore (CSI, NUS). The RF will be a member of Experimental Therapeutics Laboratory lead by Prof Boon-Cher Goh. The mission of the Experimental Therapeutics Laboratory is to identify new cancer biomarkers that could stratify high risk cancers for treatment interventions; and to develop novel therapeutic agents and delivery platforms to provide better treatment options for cancer patients. Nasopharyngeal carcinoma (NPC) is a solid tumour whose aetiology is closely linked to EBV infection. While Prof Goh’s clinical team are actively conducting clinical trials on the different therapeutic agents and treatment regimens for NPC; the lab team are focused on understanding cellular and molecular changes that occur in the malignant cells and within the tumour microenvironment that contribute to cancer progression and development of drug resistance. The role of the RF is to develop cancer vaccines and therapeutics specifically for the treatment of NPC. The position is available from October 2021 onwards for 3 years.

Roles and Responsibilities

  1. To examine the role of identified target molecules in NPC cell survival and function; corelating results with patient sample data and clinical information.
  2. To design immunogens and explore the different platforms for vaccine development.
  3. To design and conduct experiments to test vaccine prototypes in vitro and in mouse models, focusing on but not restricted to
    • a. their efficacies in stimulation the immune system and characterising the cellular and   humoral immune responses
    • b. effects of vaccine on physiological functions, bone marrow function, thrombotic events etc
    • c. Effects of vaccine in tumour-bearing mice
  4. To design and test novel therapeutic agents when appropriate.
  5. To help supervise RAs and mentor PhD students.

Actions for interested applicants

Please submit applications including (1) a covering letter that explains why you are suited to this post, (2) a detailed CV, include education qualification, employment history, and research track record, (3) the contact details (telephone and emails) of 2 referees.

Please note that only short-listed candidates will be contacted.



  • PhD in Biomedical Sciences, or related fields.
  • Strong background and working knowledge of molecular biology and cellular biology techniques.
  • Firm understanding of cancer biology and immunology.
  • Strong mammalian cell tissue culture.
  • Proficiency in spoken and written English, able to contribute to the writing of grants and manuscripts.
  • Able to communicate well and demonstrate teamwork.


  • Experience in working with mouse models.
  • Highly motivated and innovative to work independently, which strong troubleshooting abilities.
  • Able to work under pressure and deal with stress.
  • Preferable 1-2 years post graduate experience.
  • Able to commence within 3 months of confirmation.
  • Able to conduct literature reviews on the related research topis.

Covid-19 Message At NUS, the health and safety of our staff and students is one of our utmost priorities and COVID-vaccination supports our commitment to ensure the safety of our community and to make NUS as safe and welcoming as possible. Many of our roles require significant amount of physical interactions with student / staff / public members. Even for job roles that can be performed remotely, there will be instances where on-campus presence is required.

With effect from 15 January 2022, based on Singapore’s legal requirements, unvaccinated workers will not be able work at the NUS premises. As such, we regret to inform that job applicants need to be fully COVID-19 vaccinated for successful employment with NUS.[1]

[1]  MOM Updated advisory on COVID-vaccination at the Workplace, subject to changes in accordance with the national COVID-19 measures

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