NATIONAL UNIVERSITY OF SINGAPORE

Research Fellow, Bioinformatician, Cancer Science Institute

Location
Singapore
Posted
15 Jun 2022
End of advertisement period
15 Jul 2022
Ref
7713744
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Permanent
Hours
Full Time

Job Description

A postdoctoral position is available immediately in A/Prof Polly Chen’s groups for a highly motivated PhD graduate with experience in Bioinformatics (computational genomics). The focus of A/P Polly Chen’s lab is on the transcriptome-wide identification of RNA changes (e.g., RNA editing, alterative splicing, altered protein-RNA interactions, etc) in tumors and functional investigation of these changes in cancer.

Duties And Responsibilities

Candidates should have strong background in bioinformatics, genomics/transcriptomics, computer science, statistics, or other related fields. Those who are interested in computational genomics and transcriptomics, particularly in analysis and integration of various genomics/transcriptomics data, are encouraged to apply. The successful candidate will analyze and integrate in-house NGS datasets (bulk and single-cell RNA-seq, spatial transcriptomics, DNA-seq, eCLIP-seq, MeDIP-seq, etc) and also utilize publicly available genomic/transriptomics/clinical data sets to identify novel biological biomarkers/patterns and regulatory mechanisms.

Candidates are required to have a strong quantitative and statistics background, as well as strong programming skills (e.g. Python, Perl, C, C++, Java, R, or other related programming knowledge), and excellent skills in handling genomic, transcriptomic and proteomic databases. Experience in analyzing RNA editing, alternative splicing, RNA binding sites using the bulk and single-cell RNA-seq, eCLIP-seq, spatial transcriptomic data is a plus.

Qualifications

  • A PhD graduate with relevant experience in areas of computational biology/bioinformatics
  • Extensive knowledge and experience in working with a variety of NGS datasets, pipeline development and algorithm development
  • Strong publication track record, indicated by first author publications in high quality journals
  • Strong analytical skills and programming skills
  • Ability to write/contribute to research articles, grants and keep meticulous notes/proper scientific documentation
  • Strong interpersonal, written and oral communication skills
  • A strong team focus and ability to work independently

Covid-19 Message

At NUS, the health and safety of our staff and students are one of our utmost priorities, and COVID-vaccination supports our commitment to ensure the safety of our community and to make NUS as safe and welcoming as possible. Many of our roles require a significant amount of physical interactions with students/staff/public members. Even for job roles that may be performed remotely, there will be instances where on-campus presences are required.

In accordance with Singapore's legal requirements, unvaccinated workers will not be able to work on the NUS premises with effect from 15 January 2022. As such, job applicants will need to be fully COVID-19 vaccinated to secure successful employment with NUS.

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