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Research Associate

Employer
KINGS COLLEGE LONDON
Location
London (Central), London (Greater) (GB)
Salary
£38,826 - £39,882 per annum, including London Weighting Allowance
Closing date
3 Jul 2022

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Academic Discipline
Life sciences
Job Type
Research Related, Research Associate
Contract Type
Fixed Term
Hours
Full Time

Job Details

Job description

A postdoctoral fellow position is available in the laboratory of Robert Köchl in the Department of Immunobiology at King’s College London. 

The Köchl lab together with ImmTune Therapies are interested in developing improved methods of generating CAR T cells. In this project we will transfect T cells with chimeric antigen receptor constructs and then characterize both the phenotype of these cells as well as their ability to lyse target cells in vitro and in vivo

 

Talented and motivated applicants passionate about doing research at the interface of biotech and academia are invited to apply for this postdoctoral position. The position is initially for a year. 

 

This post will be offered on an a fixed-term contract for 12 months 

This is a full-time post - 100% full time equivalent

 

 

Key responsibilities

•       Work with mice  

•       Isolate immune cells from mouse tissues 

•       Culture and transfect cells either on their own or in co-culture systems 

•       Analyze cells by flow cytometry 

•       Carry out histology on tissue sections from mice 

 

The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.  

Skills, knowledge, and experience 

Essential criteria  

1.       Undergraduate degree in Biological/Biomedical Sciences or related subject 

2.       PhD awarded in Immunology, Cell Biology, Molecular Biology or related subjects  

3.       Extensive experience in purifying T and B cells from mouse organs or blood 

4.       Extensive experience in viral transduction methods for T cells to overexpress genes and to make CAR T cells 

5.       Experience of working with primary human immune cells. 

6.       Extensive experience and knowledge about phenothying T cell subsets as well as other immune cell types 

7.       Multi-colour flow cytometric staining and analysis 

 

Desirable criteria

8.       Holder of a Home Office Personal License 

9.       Experience with Microscopy 

10.   Experience with Biochemistry experiments, such as immuno blotting

Company

King's College London is one of the top 20 universities in the world and among the oldest in England. King's has more than 27,600 students (of whom nearly 10,500 are graduate students) from some 150 countries worldwide, and some 6,800 staff.

King's has an outstanding reputation for world-class teaching and cutting-edge research. In the 2014 Research Excellence Framework (REF) King’s was ranked 6th nationally in the ‘power’ ranking, which takes into account both the quality and quantity of research activity, and 7th for quality according to Times Higher Education rankings. Eighty-four per cent of research at King’s was deemed ‘world-leading’ or ‘internationally excellent’ (3* and 4*). The university is in the top seven UK universities for research earnings and has an overall annual income of more than £684 million.

King's has a particularly distinguished reputation in the humanities, law, the sciences (including a wide range of health areas such as psychiatry, medicine, nursing and dentistry) and social sciences including international affairs. It has played a major role in many of the advances that have shaped modern life, such as the discovery of the structure of DNA and research that led to the development of radio, television, mobile phones and radar.

King's College London and Guy's and St Thomas', King's College Hospital and South London and Maudsley NHS Foundation Trusts are part of King's Health Partners. King's Health Partners Academic Health Sciences Centre (AHSC) is a pioneering global collaboration between one of the world's leading research-led universities and three of London's most successful NHS Foundation Trusts, including leading teaching hospitals and comprehensive mental health services. For more information, visit: www.kingshealthpartners.org.

King’s £600 million campaign, World questions|KING’s answers, has delivered huge global impact in areas where King’s has particular expertise. Philanthropic support has funded new research to save young lives at Evelina London Children’s Hospital; established the King’s Dickson Poon School of Law as a worldwide leader in transnational law; built a new Cancer Centre at Guy’s Hospital; allowed unique collaboration between leading neuroscientists to fast-track new treatments for Alzheimer’s, Parkinson’s, motor neurone disease, depression and schizophrenia at the new Maurice Wohl Clinical Neuroscience Institute; created the Cicely Saunders Institute: the first academic institution in the world dedicated to palliative care, and supported the King’s Sierra Leone Partnership in the Ebola crisis. Donations provide over 300 of the most promising students with scholarships and bursaries each year. More information about the campaign is available at www.kcl.ac.uk/kingsanswers.

Company info
Mini-site
KINGS COLLEGE LONDON
Telephone
+(44)02078365454
Location
STRAND
LONDON
WC2R 2LS
United Kingdom

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