Post-doctoral Research Associate

Location
London (Central), London (Greater) (GB)
Salary
£39,882-£42,239 per annum, including London Weighting Allowance
Posted
23 May 2022
End of advertisement period
12 Jun 2022
Ref
046645
Academic Discipline
Life sciences
Contract Type
Fixed Term
Hours
Full Time

Job description

Applications are invited for a 12 month Post-Doctoral Research Associate position in the Department of Diabetes at King’s College London, working with Prof. Shanta Persaud’s group. 

The project is focused on determining the effects of C1QL1-derived proteins on isolated mouse and human islet function in vitro and on glucose homeostasis in mice in vivo. The post holder will use in vitro molecular/cell biology and in vivo techniques and results arising from this study will build on our ongoing research investigating how C1QL1-derived proteins improve islet function and also identify whether long term administration in vivo has beneficial effects on glucose homeostasis through increased insulin secretion and/or beta-cell mass.  

The successful candidate will have a PhD in a relevant biomedical sciences subject and have expertise in using mouse models for metabolic studies and/or in vitro assessment of cell function. Prior experience of islet biology research would be an advantage. 

This post will be offered on a fixed-term contract for 12 months 

This is a full-time post - 100% full time equivalent

Key responsibilities

•       Management of the research project on a day-to-day basis 

•       Maintaining lines of communication with Prof. Shanta Persaud. 

•       Integrating within the wider Department of Diabetes at King’s College London. 

•       Supervision of MSc/BSc/visiting students where required. 

•       Presenting work at national and international conferences. 

The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.

Skills, knowledge, and experience 

Essential criteria  

1.       PhD in a relevant biomedical sciences subject 

2.       Expertise in using mouse models for metabolic studies, including diet-induced obesity, glucose tolerance tests, insulin tolerance tests  

3.       Expertise in general molecular cell biology techniques such as cell/tissue culture, qRT-PCR, immunoblotting, immunoassays, (immuno)histochemistry.    

4.       Good communication (both written and verbal) and presentation skills. 

5.       Self-motivated, ability to work independently. 

Desirable criteria

1.       Experience with isolation and functional analysis of islets of Langerhans. 

2.       Experience of G protein-coupled receptor research

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