Work type: Full-time
Department: Department of Chemistry (25200)
Categories: Academic-related Staff

Applications are invited for appointment as Post-doctoral Fellow in the Department of Chemistry (Ref.: 515042), to commence as soon as possible for one year, with the possibility of renewal subject to satisfactory performance.

Applicants should possess a Ph.D. degree in biochemistry, molecular biology, cell biology or equivalent.  They should have a strong sense of responsibility, good organizational and leadership skills, the ability to work independently and be self-motivated.  The appointee will work on the research area of “Epigenetics in Development and Cancer” under the supervision of Professor Xiang David Li.  The research will focus on the development of novel chemical tools and methods to interrogate epigenetic modifications and biologically important protein-protein interactions.  

Specific directions include:

• development of chemical proteomics approaches to identify and characterize regulatory enzymes and effector proteins of histone epigenetic modifications;
• (semi)synthesis of site-specifically-modified histones and biochemical/physical characterization of the effects of the modification on chromatin structure and dynamics;
• development of chemical probes targeting the epigenetic family (onco)proteins;
• development of multifunctional tool molecules to study protein-protein interactions in different biological models. 

Enquiries about the duties of the post should be sent to Professor Xiang David Li.at xiangli@hku.hk.

A highly competitive salary commensurate with qualifications and experience will be offered, in addition to annual leave and medical benefits.

The University only accepts online application for the above posts.  Applicants should apply online and upload an up-to-date C.V.  Review of applications will commence as soon as possible and continue until July 31, 2022, or until the posts are filled, whichever is earlier.