A full-time research project technician is required to provide laboratory support for the Mann lab and contribute to on-going research projects. The main project will focus on understanding how cellular metabolism regulates cell fate decisions in the developing auditory system. The project will involve working with both avian and mammalian model systems.
The technician will be responsible for maintaining laboratory plasmid stocks and cloning, solution preparation for histology, microdissection and primary tissue culture, shipping and record-keeping, materials monitoring and ordering and keeping the lab and equipment in good order.
The technician will work closely with members of the Mann lab group to aid their experiments and allow smooth running of the lab. Experience in mouse/and or chick work and an active Home Office Personal License or equivalent are highly desirable. Experience in developmental or cell biology and molecular techniques will be beneficial.
The research focus of the Centre for Craniofacial and Regenerative Biology is to investigate the mechanisms that control the development and repair, of tissues and organs of the head. The Centre is committed to underpinning a broader understanding of the genetic basis of craniofacial malformations and disease. Our research is multidisciplinary, spanning numerous experimental models and techniques to explore cell signalling, transcriptional networks and cell behaviour during development, disease and regeneration. Additionally, there is a growing interest in understanding the in vivo function and biology of stem cells in different craniofacial organs as well as their potential uses for clinical therapies involving the enhancement of natural repair processes and regenerative approaches.
The department has over 60 research staff and major funding from the Medical Research Council, Biotechnology and Biomedical Science Research Council, ARC, Wellcome Trust and European Union. All the groups occupy newly refurbished laboratories and core facilities on floor 27 of Guy’s Tower.
This post will be offered on a fixed-term contract for 2.5-3 years
This is a full time post - 100% full time equivalent
- To perform regular lab duties related to the project.
- To carry out research related to the project including sample collection and processing, microdissection of avian and mammalian inner ear structures, imaging and image analysis, cloning.
- To prepare and maintain solution stocks, help with ordering and aid the running of the lab.
- To work to an appropriate level of health and safety and perform such jobs as required for effective running of the laboratory.
- To maintain an up to date and comprehensible record of all laboratory work and experiments ensuring results are accessible and complete.
- To work in a timely and organised fashion to complete pieces of work, produce reports and/or analyses that will contribute to scientific discussion.
- To manage the running of the lab: coordinating with researchers and Dr Mann.
Skills, knowledge, and experience
1. BSc in Biomedical Sciences or equivalent.
2. Excellent practical animal handling skills.
3. Excellent written and verbal communication skills.
4. Good general lab skills.
5. Ability to work in a multidisciplinary team.
6. Problem solving skills.
7. Organised record keeping and experimental planning.
1. BSc/MSc level experience in a biomedical sciences subject.
2. Experience of molecular biology and developmental biology techniques.
3. Experience with histology techniques.
4. Experience with imaging and imaging analysis.
This post is subject to Disclosure and Barring Service and Occupational Health clearance.