UNIVERSITY COLLEGE DUBLIN (UCD)

UCD Post-doctoral Research Fellow Level 2

Location
Dublin
Posted
21 Jan 2022
End of advertisement period
12 Apr 2022
Ref
014113
Contact
University College Dublin
Contract Type
Temporary
Hours
Full Time

Applications are invited for a Temporary post of a UCD Post-doctoral Research Fellow Level 2 within UCD School of Medicine/Charles Institute of Dermatology

The UCD Charles Institute of Dermatology has an ongoing research program led by Prof. Des Tobin to investigate pigment cell (melanocyte) biology in health and disease. Diversity of human skin colour is regulated at intrinsic (i.e., constitutive) and extrinsic (i.e., facultative) levels.

The former refers to an individual's genetically-determined amount/type of melanin, while the latter refers to the sensitivity/propensity of our skin to respond to stimulated pigmentation from sources that can be intrinsic (e.g., secreted melanotropic molecules) or extrinsic (e.g., UVR). Importantly, human skin phototype reflects relative activity, rather than absolute number, of melanocytes. As an interface tissue, human skin is subjected to a wide range of stimuli, some of which induce stable, reversible and/or heritable, changes in how genes function, a way that does not result in DNA sequence change.

Our knowledge of such `epigenetic' control of pigmentation in human skin is still in its infancy and is the focus of this project. We will ask if epigenetic regulation of human skin pigmentation at baseline is similar or different to stimulated pigmentation, and if different, whether differential regulation is influenced by particular epigenetic events.

Salary: €46,442-€47,764 per annum

Appointment on the above range will be dependent on qualifications and experience

Closing date: 17:00hrs (local Irish time) on 11th October 2022

Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications. UCD do not require assistance from Recruitment Agencies. Any CV's submitted by Recruitment Agencies will be returned.

Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.