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Postdoctoral Research Associate

Employer
KINGS COLLEGE LONDON
Location
London (Greater) (GB)
Salary
£38,826-£45,649 per annum, including London Weighting Allowance
Closing date
6 Jan 2022

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Job Details

Job description

Applications are invited for the position of Post-Doctoral Research Assistant in the Diabetes Research Group at King’s College London, working in the laboratory of Professor Peter Jones in collaboration with Dr Chloe Rackham at the University of Exeter on a project entitled  Improving beta cell function by mesenchymal stromal cells: novel mechanisms and cell-free translational potential”. The project is focused on improving human islet transplantation as a therapy for type 1 diabetes and will investigate the mechanisms of how mesenchymal stromal cells improve the functional survival of human islets in vitro and in vivo. The postholder will have a background in in vitro assessment of cell function and a knowledge of mouse models of islet transplantation.   

 

Minimum qualifications are a PhD in a relevant subject with molecular/cell biology skills and an interest in translating in vitro observations into in vivo models.   

 

•        PhD in a relevant biomedical sciences subject. 

•        Expertise in in vitro assessment of cell function.  

•        Prior experience with isolating and using islet of Langerhans would be an advantage. 

•        Home Office Licence would be an advantage. 

 

This post will be offered on an a fixed-term contract until 30 Sep 2023. 

This is a full-time post - 100% full time equivalent

 

Key responsibilities

•       Management of the research project on a day-to-day basis, maintaining lines of communication with Prof Jones and Dr Rackham.  

•       Integrating with the wider Department of Diabetes at King’s College London. 

•        Liaising with the University of Exeter, including short research visits. 

•        Supervision of MSc/BSc students where required. 

 

The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.  

Skills, knowledge, and experience 

Essential criteria  

1.      Expertise in general molecular cell biology techniques such as cell/tissue culture, qRT-PCR, immunoblotting, immunoassays, (immuno)histochemistry.    

2.      Expertise in in vitro assessment of cell function including viability, apoptosis, proliferation, ATP generation, secretory capacity.  

3.      Willingness to contribute to in vivo studies of islet transplantation in mouse models of diabetes. 

4.      Willing and able to work in a team. 

5.      Ability to keep clear and well-organized laboratory notes and records. 

6.      Ability to plan and prioritise workload. 

7.      Good communication (both written and verbal) and presentation skills. 

8.      Self-motivated, ability to work independently. 

 

Desirable criteria

•        Experience with isolating and using islet of Langerhans. 

•        Experience in isolating and characterizing extracellular vesicles. 

•        Experience of using mouse models for metabolic studies, or for islet transplantation studies.  

 
 

Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6.

Company

King's College London is one of the top 20 universities in the world and among the oldest in England. King's has more than 27,600 students (of whom nearly 10,500 are graduate students) from some 150 countries worldwide, and some 6,800 staff.

King's has an outstanding reputation for world-class teaching and cutting-edge research. In the 2014 Research Excellence Framework (REF) King’s was ranked 6th nationally in the ‘power’ ranking, which takes into account both the quality and quantity of research activity, and 7th for quality according to Times Higher Education rankings. Eighty-four per cent of research at King’s was deemed ‘world-leading’ or ‘internationally excellent’ (3* and 4*). The university is in the top seven UK universities for research earnings and has an overall annual income of more than £684 million.

King's has a particularly distinguished reputation in the humanities, law, the sciences (including a wide range of health areas such as psychiatry, medicine, nursing and dentistry) and social sciences including international affairs. It has played a major role in many of the advances that have shaped modern life, such as the discovery of the structure of DNA and research that led to the development of radio, television, mobile phones and radar.

King's College London and Guy's and St Thomas', King's College Hospital and South London and Maudsley NHS Foundation Trusts are part of King's Health Partners. King's Health Partners Academic Health Sciences Centre (AHSC) is a pioneering global collaboration between one of the world's leading research-led universities and three of London's most successful NHS Foundation Trusts, including leading teaching hospitals and comprehensive mental health services. For more information, visit: www.kingshealthpartners.org.

King’s £600 million campaign, World questions|KING’s answers, has delivered huge global impact in areas where King’s has particular expertise. Philanthropic support has funded new research to save young lives at Evelina London Children’s Hospital; established the King’s Dickson Poon School of Law as a worldwide leader in transnational law; built a new Cancer Centre at Guy’s Hospital; allowed unique collaboration between leading neuroscientists to fast-track new treatments for Alzheimer’s, Parkinson’s, motor neurone disease, depression and schizophrenia at the new Maurice Wohl Clinical Neuroscience Institute; created the Cicely Saunders Institute: the first academic institution in the world dedicated to palliative care, and supported the King’s Sierra Leone Partnership in the Ebola crisis. Donations provide over 300 of the most promising students with scholarships and bursaries each year. More information about the campaign is available at www.kcl.ac.uk/kingsanswers.

Company info
Mini-site
KINGS COLLEGE LONDON
Telephone
+(44)02078365454
Location
STRAND
LONDON
WC2R 2LS
United Kingdom

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