Research Associate in Health Economics
We are looking to recruit an excellent, self-motivated health economist to undertake decision-analytic modelling and trial-based economic evaluations in the areas of breast and cervical cancer screening, renal medicine, and schizophrenia. This role requires economic modelling expertise, as well as competence in the technical software needed to undertake such modelling (e.g., Excel, R, TreeAge or Simul8).
Projects the postholder will work on include:
(1) The Prospects trial (https://medphys.royalsurrey.nhs.uk/prospects/). A 7-year multi-centre clinical trial which aims to explore the cost-effectiveness of breast cancer screening using digital breast tomosynthesis. The postholder will conduct an interim budget impact analysis and adapt an existing economic model for breast cancer screening.
(2) The STARRT-AKI trial (https://www.thebottomline.org.uk/summaries/icm/starrt-aki/). A 7-year multinational clinical trial which aims to compare the cost-effectiveness of accelerated initiation of renal replacement therapy compared to standard initiation in critically ill patients with severe acute kidney injury. The postholder will analyse the trial data, observational data and other relevant databases (such as Hospital Episode Statistics (HES) data and the Renal registry) to support the development of a de novo discrete event simulation (DES) model.
(3) The YouScreen trial (https://www.eastlondonhcp.nhs.uk/aboutus/youscreen.htm). A pragmatic implementation feasibility clinical trial which aims to compare the cost-effectiveness of HPV self-sampling versus no self-sampling for women aged 25-64 years who are overdue cervical screening by at least 6 months (i.e., non-attenders). The postholder will help to analyse the trial data and develop/adapt an economic model for cervical cancer screening.
(4) The PAT trial (https://fundingawards.nihr.ac.uk/award/NIHR200756). This study aims to compare the cost-effectiveness of a pharmacogenetics test to predict psychotic patients’ response to antipsychotic treatment versus no test based on big data collected from CRIS (https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/). The postholder will help to analyse the trial data and adapt an existing whole disease model for schizophrenia.
The postholder will work under the supervision of Dr Huajie Jin and Professor Sarah Byford. The role will be based within King’s Health Economics (KHE) ( https://www.kcl.ac.uk/research/khe) which is situated at the Denmark Hill campus. The postholder will have the opportunity to join a thriving health economics research group with 25 years of experience undertaking health economic evaluations in collaboration with clinical collaborators across the UK and internationally. Candidates who are interested in doing a part-time PhD alongside their job are welcome.
This post will be fixed term until 30 September 2024.
This is a full-time post - 100% full time equivalent. Job share, part-time and flexible working will be considered.
• To work on a range of economic evaluations (including within trial and/or economic modelling), under the supervision of Dr Huajie Jin, or other senior members of the KHE team.
• Undertake statistical and economic analyses and decision modelling to support KHE economic evaluations.
• Undertake structured literature searches to identify appropriate parameters and unit costs for trial-based analyses and economic models.
• Contribute to the drafting of reports and publications on the results of economic evaluations.
• Contribute to the dissemination of scientific results by means of writing or contributing to papers for publication, presenting orally and in poster form at internal and external meetings, seminars and conferences.
• Liaise with the King’s Clinical Trials Unit to support the collection of trial data and ensure that Standard Operating Procedures are followed including appropriate storage of personal data.
• Any other duties as appropriate to the grade, as directed by the line manager..
The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.
Skills, knowledge, and experience
The job requires post-graduate health economics research skills and good knowledge and experience of a range of research methods, including systematic literature review, data collection monitoring, data cleaning, data analysis and economic modelling. The post holder must be able to contribute to research paper production.
1. Postgraduate degree in health economics or related subject (e.g., economics, operational research, medical statistics, etc.)
2. Experience of applied health economics research, including health economic evaluations, both within-trial and using economic modelling
3. Experience or good knowledge of different modelling methods (e.g., decision tree, Markov model and discrete event simulation)
4. Experience of economic modelling packages (e.g., Excel, R, TreeAge or SIMUL8)
5. Experience of statistical/econometric packages (e.g., STATA or R)
6. Experience of literature review of economic studies
7. Experience of reference management software (e.g., Endnote or RevMan)
8. Experience of word processing, databases and spreadsheets
9. Good written communication skills - ability to write coherently about a range of topics and to target writing to a range of audiences
10. Highly organised and meticulous in management and conduct of research
1. PhD in relevant area or at near completion of PhD
2. Experience of working on large databases, such as Hospital Episode Statistics (HES)
3. Evidence of peer-reviewed publications
4. Knowledge of the healthcare system in the UK
We particularly welcome applications from candidates from diverse and minority communities and backgrounds, including those with disabilities, as they are under-represented within the university at this level.