Job Description

Research Fellow Position in the Chng Lab in Department of Chemistry at NUS

A research fellow position is available from Oct 2021 in the laboratory of Associate Professor Shu-Sin Chng (http://www.chemistry.nus.edu.sg/people/academic_staff/ChngShuSin.htm).

Our research program lies at the interface of chemistry and biology, and involves the use of chemical, biochemical, genetic and biophysical approaches to characterize both the chemistry and biology of a given system. Our group is interested in membrane biogenesis, i.e. how a biological membrane is assembled. Membrane lipid bilayers form the basis for life, physically defining cells and organelles, and modulating the chemical environments within these compartments for optimal metabolism and growth. Despite these fundamental roles, however, our understanding of membrane biogenesis has remained rudimentary; we do not know how a cell makes more of itself. Conceptually, the assembly of a membrane involves acquisition of its protein and lipid constituents from another compartment where these molecules are synthesized. For lipids, this entails transport from one membrane to another, usually across an aqueous environment. Our research group is focused on using bacterial outer membranes as models to understand membrane biogenesis. Specifically, we are interested in elucidating the mechanisms of inter-membrane phospholipid and mycolic acid trafficking in Gram-negative bacteria and mycobacteria, respectively.

We are recruiting a research fellow to join us in our efforts to understand lipid trafficking in bacteria. Candidates must hold a Ph.D. degree (or equivalent) in biochemistry, chemistry or related fields. Candidates with strong expertise in structural biology, e.g. application of cryo-EM to solve protein structures, are preferred. The position is available for an initial instance of 12 months, and renewal based on performance. Competitive salary will be offered to candidates who fulfil the requirements for the position. Interested candidates should direct queries and send their applications via email to Shu-Sin (chmchngs@nus.edu.sg). Email submissions must include a CV, a one-page summary of previous research experiences, and the contact details of three potential references.

Qualifications

• Qualifications / Discipline: Ph.D. degree (or equivalent)  biochemistry, chemistry or related fields
• Skills and Experience: Strong expertise in structural biology, particularly application of cryo-EM to solve protein structures

More Information

Location: Kent Ridge Campus
Organization: Science
Department : Chemistry
Employee Referral Eligible: No
Job requisition ID : 7705