UNIVERSITY COLLEGE DUBLIN (UCD)

Research Assistant,School of Biomolecular&Biomedical Science

Location
Dublin
Posted
07 Sep 2021
End of advertisement period
28 Sep 2021
Ref
013626
Contact
University College Dublin
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Temporary
Hours
Full Time

Applications are invited for a Temporary post of a Research Assistant within UCD School of Biomolecular and Biomedical Science

Current treatments for prostate cancer mainly target the Androgen Receptor (AR), however despite initial response these treatments fail. Triple negative breast cancer (TNBC) is an aggressive form of breast cancer for which there are no targeted therapies.

Due to the fact that a proportion of TNBC express AR and that AR expression has been associated with poor prognosis, targeting AR in TNBC is attracting increasing interest. Our lab focuses on alternative ways of targeting AR by inhibiting key co-regulators and secondary transcription factors involved in AR action; therefore bypassing AR resistance mechanisms. Among these AR interactors, we have identified Serum Response Factor (SRF) as a promising alternative point of therapeutic intervention.

The main aim of this project is to elucidate the molecular mechanisms behind SRF and AR cross-talk in vitro, in vivo and in patients, with the remit of identifying novel molecular targets independent of AR resistance mechanisms. Applications are invited for a Research Assistant to aid in delivering this project. The successful candidate will conduct specified laboratory research experiments and analysis of results as part of the project.

Salary Range: €26,609 - €31,701 per annum

Appointment on the above range will be dependent upon qualifications and experience.

Closing date: 17:00hrs (local Irish time) on 28th September 2021

Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications. UCD do not require assistance from Recruitment Agencies. Any CV's submitted by Recruitment Agencies will be returned.

Prior to application, further information (including application procedure) should be obtained from the Work at UCD website: https://www.ucd.ie/workatucd/jobs/.