Instrument Technician (Mass Spectrometry)
The Faculty of Natural, Mathematical and Engineering Sciences (NMES), King’s College London, is seeking a committed, professional and motivated individual to join a large and talented technical team as a Mass Spectrometry technician in the Department of Chemistry
The post holder is a member of the Faculties professional services team, providing high quality technical support to the Faculty and specific support to its research activities. The role purpose is:
- To provide expertise in the advanced operation of LC-MS mass spectrometry within the Department of Chemistry.
- To forge relationships with colleagues in the School, Faculty and university, in order to contribute to process development and adoption of best practice.
- To provide advice and guidance and, where appropriate, training on University policies, processes and where required, source information and support for colleagues to facilitate their work.
- To work closely with all relevant members of the Department’s academic, professional and technical services teams and other colleagues.
More specifically, the post holder will:
- Proactively manage and develop the Mass Spec services (high and low resolution) provided for research scientists.
- Provide an expert, problem-solving service to researchers involving data collection, interpretation and reporting.
- Provide expert guidance and advice to other technical staff who assist with provision of the services.
- Provide training, advice and guidance to research students and staff in the use of Waters UPLC- Xevo G2-XS Q-ToF, and techniques or software appropriate to synthetic chemistry and biochemistry.
- Provide training, advice and guidance to research students and staff in the use of Shimadzu GCMS and Agilent LC/MS systems.
- Contribute directly to the research activities of the department through collaboration across a range of research projects.
- Research, implement and apply new methods and experimental protocols reflecting contemporary developments in mass spec techniques to the benefit of facility and service users.
- Manage the upkeep and development of Waters UPLC- Xevo G2-XS Q-ToF, Shimadzu GCMS, Agilent LC/MS including software management, systems calibrations, troubleshooting and liaising with system engineers as appropriate.
- Provide an expert QTof service to external collaborators.
- Develop and maintain user guidance notes and instruction manuals.
- Prepare risk assessments for chemical laboratory environments, including CoSHH.
- Maintain records of instrument repairs, upgrades, and calibrations.
- Maintain appropriate service records suitable for monitoring its usage.
- Support routine maintenance of complex laboratory equipment (e.g. NMR) as directed by the line manager (training will be provided as required).
- Act as cover for certain technical duties when needed.
- Adhere to any relevant risk assessments and safe working practices.
- Support equality of opportunity and equity of treatment to all staff and students.
- Contribute to a culture of professionalism and customer service.
- Undertake any other reasonable tasks, including operational or administrative duties, as requested.
This post will be offered on an indefinite contract
This is a full-time post, 35 hours per week
- Manage and develop the Mass Spec services provided for research scientists in the department and externally.
- Provide an expert, problem-solving service to researchers involving data collection, interpretation and reporting with Waters UPLC- Xevo G2-XS Q-ToF system.
- Provide training, guidance and advice to research staff and students in the use of Waters Q-ToF, Shimadzu GCMS and Agilent LC/MS, techniques and software.
- To manage the upkeep and development of Waters Q-ToF, Shimadzu GCMS and Agilent LC/MS including software management, system calibrations, troubleshooting and liaising with system engineers as appropriate
The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.
Skills, knowledge, and experience
1. First degree or equivalent experience in a relevant discipline and have significant academic or industrial experience directly relevant to the post.
2. Background in chemistry, biochemistry or related subject.
3. Hands on experience of running samples by LC-MS/MS and Waters UPLC- Xevo G2-XS Q-ToF.
4. Experience of operating equipment with Waters MassLynx and/or UNIFI.
5. Experience of working in a research environment and contributing effectively to the work of chemistry research groups in an educational environment.
6. Fault diagnosis and repair skills, manual skills for dismantling and cleaning ion sources, removal and replacement of faulty parts, etc.
7. Ability to work enthusiastically and effectively as part of a team.
8. Ability to deal with different tasks and priorities.
9. Ability to learn new techniques.
10. Good communication skills and ability to interact positively with staff at every level.
1. Experience operating Shimadzu GCMS, Agilent HPLC systems.
2. Hold a PhD with a substantial component of use of advanced instrumental techniques.
3. Experience of managing a mass spectrometry service or mass spectrometry service operation.