Life Science Research Professional 1

7 days left

California, United States
11 Jan 2021
End of advertisement period
11 Mar 2021
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Fixed Term
Full Time

The Department of Anesthesia is seeking a full-time Life Science Research Professional 1 (LSRP1) to participate in a cardiovascular research project. The research primarily utilizes patient-specific induced pluripotent stem cell-derived cardiomyocytes to model cardiac disorders. The successful candidate must have experience in human cell culture techniques, genomic and protein expression molecular techniques with an excellent record keeping ability and organization skills. Prior experience with induced pluripotent stem cell research is highly desired, but not a requirement. A minimal part of the project will include animal experiments and prior experience working with mice is desired. The candidate must exhibit a great deal of independence and be able to independently design experiments, carry them out and assist with analyzing and presenting data. 

Duties Include: 

  • Induced pluripotent stem cell reporgramming and culture  
  • Cardiomyocyte and endothelial differentiation experiments using human iPSCs 
  • Perform cardiomyocyte and endothelial cell phenotype and molecular evaluation protocols
  • Subcutanteous injection of drugs in pregnant mice.
  • Plan and perform existing experiments in support of ongoing research projects based on knowledge of scientific theory. Interpret and perform analyses of results.
  • Review literature on an ongoing basis to remain current with new procedures and related research.
  • Offer suggestions regarding modifications to procedures and protocols 
  • Maintain detailed records of experiments and outcomes
  • Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals
  • Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed

*- Other duties may also be assigned

Desired Qualifications:

  • A Bachelor of Science in molecular biology or related discipline or equivalent experience.
  • Two years experience.
  • Technical writing experience in SOP’s, protocols, and reports.
  • Proficiency with human cell culture techniques, experience with iPSC is highly valued.
  • Experience with laboratory animal experiments, in particular, s.c. injection of drugs.
  • Experience with tissue homogenization and single cell preparation from various tissues, primarily cardiomyocytes.
  • Proficiency with basic molecular biology techniques, such as gel electrophoresis, PCR, and recombinant DNA techniques.
  • Routinely perform cardiomyocyte and endothelial cell differentiation experiments using human iPSCs.
  • Possess initiative, ability to multi-task and a desire to acquire new technical skills.
  • Ability to work both independently and as part of a team.
  • Ability to communicate effectively with team members and collaborators.
  • Experimental design, execution of plan and presentation of data to team
  • Utilization of good documentation practices.

Education & Experience (Required):

  • Bachelor's degree in related scientific field.

Knowledge, Skills, and Abilities (Required):

  • General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
  • Demonstrated ability to apply theoretical knowledge of science principals to problem solve work. 
  • Ability to maintain detailed records of experiments and outcomes.
  • General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
  • Ability to work under deadlines with general guidance. 
  • Excellent organizational skills and demonstrated ability to accurately complete detailed work.

Physical Requirements*:

  • Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds. 
  • Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts. 
  • Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls. 
  • Must have correctible vision to perform duties of the job.
  • Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
  • Ability to lift heavy objects weighing up to 50 pounds.
  • Ability to work in a dusty, dirty, and odorous environment.
  • Position may require repetitive motion.
  • Ability to work with mice

*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

Working Conditions:

  • May require working in close proximity to blood borne pathogens.
  • May require work in an environment where animals are used for teaching and research.
  • Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present. 
  • Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator. 
  • May require extended or unusual work hours based on research requirements and business needs.

Additional Information

  • Schedule: Full-time
  • Job Code: 4945
  • Employee Status: Fixed-Term
  • Grade: E
  • Requisition ID: 88148

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