Research Assistant 1 MS

Connecticut, United States
29 Dec 2020
End of advertisement period
27 Feb 2021
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Fixed Term
Full Time

Position Focus:

Under the direction of the principal investigator, contribute to the laboratory’s efforts to study neurodegenerative disease mechanisms using human induced pluripotent stem cells (iPSCs) and genetically modified mice as model systems. This position will support research projects and assist with general lab organization/reagent preparation. Principle techniques will include mammalian cell culture, mouse colony maintenance and molecular biology.

Essential duties:

  • Assist with the ordering and maintenance of laboratory supplies.
  • Assume responsibility for monitoring, disposal and record-keeping of laboratory chemicals. Ensure that all safety regulations relating to use of hazardous chemicals and biological agents are closely followed.
  • Maintain laboratory stocks of common reagents and media.
  • Maintain a database of plasmids and cell lines.
  • Generate DNA plasmids for transfection using standard cloning methods under the direction of the principal investigator.
  • Culture and maintain human iPSCs and neurons derived from them using standard mammalian cell culture techniques.
  • Genotype genetically modified mouse lines using DNA extraction and PCR.
  • Purify and analyze DNA/RNA from human cells for sequencing analysis.

Essential Duties

  1. Researches and collects data through complex laboratory/ scientific experiments, techniques, and procedures; library research; structured interviews; or through other means for designated research assignments.
  2. Records and compiles information related to research data. Codes data accordingly to research specifications. Uses a computer terminal to input and retrieve data and to generate reports. Processes and summarizes data using scientific or statistical techniques.
  3. Assists in data interpretation and analyses. Reports on status of research activities. Sets up, operates and maintains laboratory equipment and apparatus.
  4. Formulates and prepares scientific solutions and media. Recruits study participants. Orders and maintains inventory of supplies.
  5. May assist in designing, developing, and modifying research experiments, procedures, or survey instruments. May oversee and instruct research staff.
  6. Performs additional functions incidental to research activities.

Required Education and Experience

Six years of related work experience, four of them in the same job family at the next lower level, and high school level education; or four years of related work experience and an Associate's degree; or little or no work experience and a Bachelor's degree in a related field; or an equivalent combination of experience and education.

Required Skill/Ability 1:

High degree of reliability and attention to details is critical.

Required Skill/Ability 2:

Proven enthusiasm, interest, and determined approach to scientific study.

Required Skill/Ability 3:

Excellent organizational, interpersonal and communication skills.

Required Skill/Ability 4:

Proven analytical and problem-solving skills

Required Skill/Ability 5:

Ability to work independently while functioning as part of a team.

Preferred Education, Experience and Skills:

Bachelor's degree in a related school. Basic molecular biology skills including plasmid preparation, molecular cloning and PCR. Ability to purify and analyze DNA/RNA from human cells for sequencing analysis. Experience with standard mammalian cell culture techniques. Experience with mouse colony maintenance. Prior research in cell biology or a related discipline.

Weekend Hours Required?


Evening Hours Required?


Drug Screen


Health Screening


Background Check Requirements

All candidates for employment will be subject to pre-employment background screening for this position, which may include motor vehicle, DOT certification, drug testing and credit checks based on the position description and job requirements. All offers are contingent upon the successful completion of the background check. Please visit for additional information on the background check requirements and process.

Posting Disclaimer

The intent of this job description is to provide a representative summary of the essential functions that will be required of the position and should not be construed as a declaration of specific duties and responsibilities of the particular position. Employees will be assigned specific job-related duties through their hiring departments.

Affirmative Action Statement:

Yale University considers applicants for employment without regard to, and does not discriminate on the basis of, an individual’s sex, race, color, religion, age, disability, status as a veteran, or national or ethnic origin; nor does Yale discriminate on the basis of sexual orientation or gender identity or expression. Title IX of the Education Amendments of 1972 protects people from sex discrimination in educational programs and activities at institutions that receive federal financial assistance. Questions regarding Title IX may be referred to the University’s Title IX Coordinator, at, or to the U.S. Department of Education, Office for Civil Rights, 8th Floor, Five Post Office Square, Boston MA 02109-3921. Telephone: 617.289.0111, Fax: 617.289.0150, TDD: 800.877.8339, or Email:


Yale University is a tobacco-free campus

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